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Brief Title: Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL
Official Title: A Phase Ib, Open-label, Randomized Study to Assess Safety and Preliminary Efficacy of Tafasitamab in Addition to R-CHOP or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) - First-MIND
Study ID: NCT04134936
Brief Summary: This is an open-label, randomized, multicentre study to evaluate safety and preliminary efficacy of the human anti-CD19 antibody Tafasitamab in addition to R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristin, Prednison) or Tafasitamab and Lenalidomide in addition to R-CHOP in adult patients with newly diagnosed, previously untreated Diffuse Large B-cell Lymphoma (DLBCL).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
MorphoSys Research Site, Tucson, Arizona, United States
MorphoSys Research Site, Anaheim, California, United States
MorphoSys Research Site, Duarte, California, United States
MorphoSys Research Site, Encinitas, California, United States
MorphoSys Research Site, Aurora, Colorado, United States
MorphoSys Research Site, New Haven, Connecticut, United States
MorphoSys Research Site, Washington, District of Columbia, United States
MorphoSys Research Site, Urbana, Illinois, United States
MorphoSys Research Site, Louisville, Kentucky, United States
MorphoSys Research Site, Covington, Louisiana, United States
MorphoSys Research Site, Rockville, Maryland, United States
MorphoSys Research Site, Ann Arbor, Michigan, United States
MorphoSys Research Site, Rochester, Minnesota, United States
MorphoSys Research Site, Cincinnati, Ohio, United States
MorphoSys Research Site, Cleveland, Ohio, United States
MorphoSys Research Site, Eugene, Oregon, United States
MorphoSys Research Site, Charleston, South Carolina, United States
MorphoSys Research Site, Austin, Texas, United States
MorphoSys Research Site, Dallas, Texas, United States
MorphoSys Research Site, Houston, Texas, United States
MorphoSys Research Site, San Antonio, Texas, United States
MorphoSys Research Site, Tyler, Texas, United States
MorphoSys Research Site, Vancouver, Washington, United States
MorphoSys Research Site, Graz, , Austria
Medizinische Universtät Innsbruck, Innsbruck, , Austria
MorphoSys Research Site, Linz, , Austria
MorphoSys Research Site, Salzburg, , Austria
MorphoSys Research Site, St. Poelten, , Austria
MorphoSys Research Site, Vienna, , Austria
MorphoSys Research Site, Wels, , Austria
MorphoSys Research Site, Antwerpen, , Belgium
MorphoSys Research Site, Antwerpen, , Belgium
MorphoSys Research Site, Brussel, , Belgium
MorphoSys Research Site, Gent, , Belgium
MorphoSys Research Site, Roeselare, , Belgium
MorphoSys Research Site, Yvoir, , Belgium
MorphoSys Research Site, Hradec Králové, , Czechia
MorphoSys Research Site, Ostrava, , Czechia
MorphoSys Research Site, Prague, , Czechia
MorphoSys Research Site, Prague, , Czechia
MorphoSys Research Site, Prague, , Czechia
MorphoSys Research Site, Bordeaux 33076, , France
MorphoSys Research Site, Brest 29609, , France
MorphoSys Research Site, Nantes 44093, , France
MorphoSys Research Site, Pierre Benite 69310, , France
MorphoSys Research Site, Aachen, , Germany
MorphoSys Research Site, Augsburg, , Germany
MorphoSys Research Site, Bonn, , Germany
MorphoSys Research Site, Dortmund, , Germany
MorphoSys Research Site, Gießen, , Germany
MorphoSys Research Site, Göttingen, , Germany
MorphoSys Research Site, Halle, , Germany
MorphoSys Research Site, Mutlangen, , Germany
MorphoSys Research Site, München, , Germany
MorphoSys Research Site, München, , Germany
MorphoSys Research Site, Nürnberg, , Germany
MorphoSys Research Site, Würzburg, , Germany
MorphoSys Research Site, Bologna 40138, , Italy
MorphoSys Research Site, Ravenna 48100, , Italy
MorphoSys Research Site, Lisboa, , Portugal
MorphoSys Research Site, Lisbon, , Portugal
MorphoSys Research Site, Porto, , Portugal
MorphoSys Research Site, Porto, , Portugal
MorphoSys Research Site, Barcelona 8003, , Spain
MorphoSys Research Site, Caceres 10003, , Spain
MorphoSys Research Site, Girona 17007, , Spain
MorphoSys Research Site, Madrid 28041, , Spain
MorphoSys Research Site, Sabadell 8208, , Spain
MorphoSys Research Site, Sevilla 41013, , Spain
MorphoSys Research Site, Vitoria-Gasteiz 1009, , Spain
Name: Pia Kloepfer, MD
Affiliation: MorphoSys AG
Role: STUDY_DIRECTOR