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Spots Global Cancer Trial Database for dlbcl

Every month we try and update this database with for dlbcl cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Safety Study of SGN-35T in Adults With Advanced CancersNCT06120504
Lymphoma, T-Cel...
Hodgkin Disease
Lymphoma, T-Cel...
Lymphoma, Large...
Lymphoma, Large...
Lymphoma, Non-H...
SGN-35T
18 Years - Seagen Inc.
Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL.NCT00355199
Diffuse Large B...
Rituximab-HDS
Rituximab-CHOP
18 Years - 65 YearsGruppo Italiano Terapie Innovative nei Linfomi
A Phase 1/2 Study To Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid TumorsNCT02440685
Lymphoma, Large...
Lymphoma, Mantl...
Lymphoma, Folli...
Cancer
Neoplasm
Tumor
Lymphoma, Malig...
Lymphoma, B-cel...
Lymphoma, Non-H...
B-Cell Chronic ...
B-Cell Leukemia...
B-Lymphocytic L...
Chronic Lymphoc...
Leukemia, Lymph...
Leukemia, Lymph...
Myelofibrosis
Chronic Idiopat...
Idiopathic Myel...
Lymphoma, T Cel...
Peripheral T-Ce...
T-Cell Lymphoma...
ASN002 Dose Esc...
ASN002 RD
18 Years - Asana BioSciences
Safety and Efficacy of Entospletinib (ENTO [GS-9973]) Combined With Vincristine (VCR) in Adult Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NHL)NCT02568683
Non-Hodgkin Lym...
Entospletinib
Vincristine
18 Years - Gilead Sciences
R-CHOP Versus R-mini-CEOP in Elderly Patients(>65)With DLBCLNCT01148446
Elderly Patient...
Diffuse Large B...
Cyclophosphamid...
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
Prednisone
Epirubicin
Vinblastine
Rituximab
G-CSF
66 Years - 80 YearsFondazione Italiana Linfomi - ETS
Maintenance Hormonal Therapy and DLBCLNCT06355401
Diffuse Large B...
Tamoxifen 20mg
18 Years - 75 YearsSohag University
Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell LymphomaNCT05412290
B Cell Lymphoma
Aggressive Lymp...
Diffuse Large B...
High-grade B-ce...
Transformed Lym...
Follicular Lymp...
Mosunetuzumab
18 Years - Washington University School of Medicine
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma PatientsNCT04844866
Diffuse Large B...
MB-CART2019.1
R-GemOx or BR p...
18 Years - Miltenyi Biomedicine GmbH
Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCLNCT04134936
Diffuse Large B...
Tafasitamab
Tafasitamab plu...
18 Years - MorphoSys AG
Ibrutinib and Lenalidomide With Dose Adjusted EPOCH-R in Subjects With Relapsed/Refractory Diffuse Large B-cell LymphomaNCT02142049
Diffuse Large B...
Diffuse Large B...
Ibrutinib
DA-EPOCH-R
Lenalidomide
18 Years - Pharmacyclics LLC.
R-CHOP14 or R-CHOP21 &Consolidation PET-Oriented Radiotherapy (RT) in DLBCL PatientsNCT03364439
Diffuse Large B...
Treatment plan
18 Years - 80 YearsFondazione Italiana Linfomi - ETS
A Study Comparing the Efficacy and Safety Between H-CHOP and R-CHOP in Untreated CD20-Positive Diffuse Large B-cell Lymphoma PatientsNCT05040906
Recruiting
H02+CHOP
Rituxan +CHOP
18 Years - 75 YearsShandong New Time Pharmaceutical Co., LTD
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.NCT06022029
Triple Negative...
Diffuse Large B...
Follicular Lymp...
Lymphoma, Non-H...
Mantle Cell Lym...
Bladder Cancer
Uveal Melanoma,...
Cervix Cancer
Carcinoma in Si...
Head and Neck S...
Skin Cancer
Metastatic Canc...
Tumor, Solid
Tumor Recurrenc...
ONM-501
Cemiplimab
18 Years - OncoNano Medicine, Inc.
A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell LymphomaNCT03758989
DLBCL
Rituximab Predn...
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
18 Years - University of Rochester
A Phase Ib Study of Belinostat With RDHAP Chemotherapy (Dexamethasone, Cytarabine, Cisplatinum) in Adults With Relapsed or Refractory Diffuse Large B-cell LymphomaNCT02532192
Lymphoma
Belinostat
Rituximab
Cisplatin
Cytarabine
Dexamethasone
Ciprofloxacin
Fluconazole
18 Years - 80 YearsM.D. Anderson Cancer Center
A Multiple Ascending Dose Study of MEDI7247 in Patients With Selected Relapsed/Refractory Hematological MalignanciesNCT03106428
Acute Myeloid L...
Multiple Myelom...
Diffuse Large B...
MEDI7247
18 Years - 100 YearsMedImmune LLC
A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin LymphomasNCT03575351
Lymphoma, Non-H...
Standard of Car...
JCAR017
18 Years - 75 YearsCelgene
Tailoring Treatment for B Cell Non-hodgkin's Lymphoma Based on PET Scan Results Mid TreatmentNCT00324467
Lymphoma, Non-H...
Advanced Stage ...
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
Ondansetron
Dexamethasone
Diphenhydramine
Acetaminophen
Ifosfamide
Mesna (IV)
Mesna (oral)
Carboplatin
Etoposide
Rituximab
Ondansetron
Dexamethasone
Diphenhydramine
Acetaminophen
PET Scan
18 Years - British Columbia Cancer Agency
Early Treatment Stratification Based on PET Scan Response to Chemotherapy in Patients With Diffuse Large B-cell LymphomaNCT01361191
Diffuse Large B...
Follicular Grad...
R-MEGACHOP
18 Years - 65 YearsGrupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell LymphomaNCT05412290
B Cell Lymphoma
Aggressive Lymp...
Diffuse Large B...
High-grade B-ce...
Transformed Lym...
Follicular Lymp...
Mosunetuzumab
18 Years - Washington University School of Medicine
GA In NEwly Diagnosed Diffuse Large B Cell LymphomaNCT01659099
Diffuse Large B...
GA101
Rituximab
Doxorubicin
Cyclophosphamid...
Prednisone
Bleomycin
Vindesin
Vincristine
18 Years - 60 YearsThe Lymphoma Academic Research Organisation
SMOLY : Phenotype and Functions of Monocyte Subtypes in High Grade B Lymphoma: Towards New Biomarkers?NCT03672682
DLBCL
18 Years - 70 YearsRennes University Hospital
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.NCT06022029
Triple Negative...
Diffuse Large B...
Follicular Lymp...
Lymphoma, Non-H...
Mantle Cell Lym...
Bladder Cancer
Uveal Melanoma,...
Cervix Cancer
Carcinoma in Si...
Head and Neck S...
Skin Cancer
Metastatic Canc...
Tumor, Solid
Tumor Recurrenc...
ONM-501
Cemiplimab
18 Years - OncoNano Medicine, Inc.
First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228NCT05737628
Lymphoma
BYON4228 + Ritu...
18 Years - Byondis B.V.
Dose Dense Chemotherapy and Rituximab for Young High Risk Diffuse Large B-Cell Lymphoma Patients (CRY-04)NCT01502982
Diffuse Large B...
R-CHOEP14x6+HD-...
18 Years - 64 YearsNordic Lymphoma Group
Study to Learn if 200mg Test Drug (Fostamatinib) Helps People With Large B-Cell Lymphoma,a Type of Blood CancerNCT01499303
Diffuse Large B...
Fostamatinib
18 Years - AstraZeneca
A Study of AZD0486 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin LymphomaNCT04594642
B-cell Non Hodg...
Diffuse Large B...
High-grade B-ce...
Follicular Lymp...
AZD0486 IV
18 Years - 130 YearsAstraZeneca
Copanlisib With Rituximab-Bendamustine in Patients With Relapsed-Refractory Diffuse Large B-cell LymphomaNCT04433182
Diffuse Large B...
Copanlisib
18 Years - Fondazione Italiana Linfomi - ETS
Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell LymphomaNCT00869999
Diffuse Large B...
Everolimus
rituximab
18 Years - Massachusetts General Hospital
Lenalidomide, Rituximab, Gemcitabine, Oxaliplatin and Dexamethasone in Relapse and Refractory DLBCLNCT03795571
Diffuse Large B...
Diffuse Large B...
Rituximab
Gemcitabine
Oxaliplatin
Dexamethasone
Lenalidomide Or...
18 Years - 65 YearsThe First Affiliated Hospital with Nanjing Medical University
Phase I Study of MIK665, a Mcl-1 Inhibitor, in Patients With Refractory or Relapsed Lymphoma or Multiple MyelomaNCT02992483
Multiple Myelom...
MIK665
18 Years - Novartis
Efficacy and Safety of Venetoclax Combined With BEAM Pretreatment in Autologous Transplantation for DLBCLNCT05863845
Diffuse Large B...
Venetoclax
Carmustine
Cytarabine
Etoposide
Melphalan
Hematopoietic C...
18 Years - 65 YearsRuijin Hospital
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL PatientsNCT04824092
Diffuse Large B...
Tafasitamab
Lenalidomide
Rituximab
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
Tafasitamab pla...
Lenalidomide pl...
18 Years - 80 YearsMorphoSys AG
Study of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell LymphomaNCT05757700
B-Cell Lymphoma
Large B-cell Ly...
DLBCL, Nos Gene...
High-grade B Ce...
Mediastinal Lar...
19(T2)28z1xx TR...
18 Years - Memorial Sloan Kettering Cancer Center
Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First RelapseNCT03356054
DLBCL
R-DHAP
Brentuximab Ved...
18 Years - Stichting Hemato-Oncologie voor Volwassenen Nederland
Study of Betalutin for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma (LYMRIT-37-05)NCT02658968
Relapsed, Diffu...
Refractory Diff...
Betalutin
18 Years - Nordic Nanovector
GCS-100LE in Combination With Etoposide and Dexamethasone in Relapsed or Refractory Diffuse Large B-Cell LymphomaNCT00776802
Diffuse Large B...
GCS-100
Etoposide; Dexa...
18 Years - La Jolla Pharmaceutical Company
Flavopiridol to Treat Relapsed Mantle Cell Lymphoma or Diffuse Large B-Cell LymphomaNCT00445341
Lymphoma
Flavopiridol
18 Years - National Institutes of Health Clinical Center (CC)
Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell LymphomaNCT05326243
Diffuse Large B...
Primary Mediast...
Large B-cell Ly...
Follicular Lymp...
Follicular Lymp...
CD19-targeted c...
14 Years - 70 YearsPell Bio-Med Technology Co., Ltd.
Temozolomide in Treatment of Patients With Primary Central Nervous System LymphomaNCT02934204
Primary CNS Lym...
methotrexate
temozolomide
18 Years - 75 YearsGuangdong Provincial People's Hospital
GA In NEwly Diagnosed Diffuse Large B Cell LymphomaNCT01659099
Diffuse Large B...
GA101
Rituximab
Doxorubicin
Cyclophosphamid...
Prednisone
Bleomycin
Vindesin
Vincristine
18 Years - 60 YearsThe Lymphoma Academic Research Organisation
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL PatientsNCT04824092
Diffuse Large B...
Tafasitamab
Lenalidomide
Rituximab
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
Tafasitamab pla...
Lenalidomide pl...
18 Years - 80 YearsMorphoSys AG
CTL019 Out of Specification MAP for ALL or DLBCL PatientsNCT03601442
Acute Lymphobla...
Diffuse Large B...
CTL019
1 Day - 25 YearsNovartis
A Study of Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin LymphomaNCT04082936
Non-Hodgkin Lym...
Follicular Lymp...
DLBCL
Mantle Cell Lym...
Marginal Zone L...
imvotamab
18 Years - IGM Biosciences, Inc.
Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte MalignanciesNCT05541341
Diffuse Large B...
Acute Lymphobla...
Follicular Lymp...
tisagenlecleuce...
- 100 YearsNovartis
Camrelizumab Plus R-CHOP Regimen in Untreated Primary Extranodal DLBCLNCT05093140
Primary Extrano...
DLBCL
Camrelizumab
18 Years - 65 YearsSun Yat-sen University
A Safety Study of SEA-TGT (SGN-TGT) in Advanced CancerNCT04254107
Non-small Cell ...
Gastric Carcino...
Gastroesophagea...
Classical Hodgk...
Diffuse Large B...
Peripheral T-ce...
Cutaneous Melan...
Head and Neck S...
Bladder Cancer
Ovarian Cancer
Triple Negative...
Cervical Cancer
SEA-TGT
sasanlimab
brentuximab ved...
18 Years - Seagen Inc.
Phase II Study About Combination CHOP-21, Obinutuzumab and Ibrutinib in Untreated Young High Risk DLBCL Patients.NCT02670317
Lymphoma, B-Cel...
Obinutuzumab
Ibrutinib
CHOP
18 Years - 60 YearsFondazione Italiana Linfomi - ETS
KPT-330 Plus RICE for Relapsed/Refractory Aggressive B-Cell LymphomaNCT02471911
Diffuse Large B...
KPT-330
Rituximab
Etoposide
Carboplatin
Ifosfamide
Dexamethasone
18 Years - Weill Medical College of Cornell University
Study of Orelabrutinib in Combination With Gemox in Refractory / Relapsed Diffuse Large B-cell LymphomaNCT05381506
DLBCL
Orelabrutinib a...
18 Years - Sun Yat-sen University
Temozolomide in Treatment of Patients With Primary Central Nervous System LymphomaNCT02934204
Primary CNS Lym...
methotrexate
temozolomide
18 Years - 75 YearsGuangdong Provincial People's Hospital
Phase I Study of MIK665, a Mcl-1 Inhibitor, in Patients With Refractory or Relapsed Lymphoma or Multiple MyelomaNCT02992483
Multiple Myelom...
MIK665
18 Years - Novartis
Real-World Study of DLBCL With Different Genetic SubtypesNCT06026488
DLBCL - Diffuse...
Lymphoma
Other
18 Years - Ruijin Hospital
A Safety and Tolerability Study of INCB053914 in Combination With INCB050465 in Diffuse Large B-Cell LymphomaNCT03688152
Relapsed Diffus...
Refractory Diff...
INCB053914
INCB050465
18 Years - Incyte Corporation
Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic TransplantationNCT02431988
Diffuse Large B...
Leukapheresis
Cyclophosphamid...
Fludarabine
CAR19 T-Cells
16 Years - 65 YearsUniversity College, London
Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein ExpressionNCT06005870
Diffuse Large B...
Zanubrutinib pl...
18 Years - 75 YearsHuazhong University of Science and Technology
Ibrutinib in Combination With Lenalidomide and Rituximab in Participants With Relapsed or Refractory Diffuse Large B-Cell LymphomaNCT02077166
Relapsed Diffus...
Refractory Diff...
Ibrutinib
Lenalidomide
Rituximab
18 Years - Pharmacyclics LLC.
Dose Adjusted EPOCH-R, to Treat Mature B Cell MalignanciesNCT01760226
Diffuse Large B...
Post Transplant...
Primary Mediast...
DA-EPOCH-R for ...
Methotrexate
Etoposide
Doxorubicin
Vincristine
Rituximab
Cyclophosphamid...
Prednisone
G-CSF
- 30 YearsBaylor College of Medicine
Open Label Phase I Dose Escalation Study With BAY1143572 in Patients With Advanced CancerNCT01938638
Neoplasms
BAY1143572
21 Years - Bayer
PQR309 in Phase 2 in Patients With Relapsed or Refractory Primary Central Nervous System LymphomaNCT03120000
Primary Central...
PQR309
18 Years - PIQUR Therapeutics AG
A Phase II Study of Oral Panobinostat (LBH589) and Rituximab to Treat Diffuse Large B Cell Lymphoma (DLBCL)NCT01238692
Diffuse Large B...
LBH589
Rituximab
18 Years - Jewish General Hospital
Study of Betalutin for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma (LYMRIT-37-05)NCT02658968
Relapsed, Diffu...
Refractory Diff...
Betalutin
18 Years - Nordic Nanovector
Carfilzomib Plus Belinostat in Relapsed/Refractory NHLNCT02142530
Non-Hodgkin Lym...
Diffuse Large B...
Mantle Cell Lym...
Follicular Lymp...
Peripheral T-ce...
Carfilzomib
Belinostat
18 Years - Massachusetts General Hospital
A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell LymphomasNCT05934838
Follicular Lymp...
B-Cell Lymphoma
Mantle Cell Lym...
Diffuse Large B...
Tazemetostat Pi...
18 Years - Weill Medical College of Cornell University
Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and LymphomasNCT02503423
Solid Tumors
Lymphoma
ASTX660
18 Years - Astex Pharmaceuticals, Inc.
Ibrutinib and Lenalidomide With Dose Adjusted EPOCH-R in Subjects With Relapsed/Refractory Diffuse Large B-cell LymphomaNCT02142049
Diffuse Large B...
Diffuse Large B...
Ibrutinib
DA-EPOCH-R
Lenalidomide
18 Years - Pharmacyclics LLC.
ADAM17 Inhibitor/ Rituximab After Auto HCT for DLBCLNCT02141451
Diffuse Large B...
Rituximab
INCB7839
18 Years - Masonic Cancer Center, University of Minnesota
R-CHOP14 or R-CHOP21 &Consolidation PET-Oriented Radiotherapy (RT) in DLBCL PatientsNCT03364439
Diffuse Large B...
Treatment plan
18 Years - 80 YearsFondazione Italiana Linfomi - ETS
Exosomes and Immunotherapy in Non-Hodgkin B-cell LymphomasNCT03985696
Lymphoma, B-cel...
blood sample
18 Years - University Hospital, Limoges
Dose-adjusted EPOCH-R in MYC Positive DLBCLNCT01914718
Diffuse Large B...
DA-EPOCH-R
18 Years - 70 YearsFudan University
Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell LymphomaNCT05326243
Diffuse Large B...
Primary Mediast...
Large B-cell Ly...
Follicular Lymp...
Follicular Lymp...
CD19-targeted c...
14 Years - 70 YearsPell Bio-Med Technology Co., Ltd.
Split-Dose R-CHOP for Older Adults With DLBCLNCT03943901
Diffuse Large B...
DLBCL
Cancer
Rituximab
Cyclophosphamid...
Doxorubicin
Vincristine
Prednisone
Pegfilgrastim
70 Years - University of Wisconsin, Madison
Study to Learn if 200mg Test Drug (Fostamatinib) Helps People With Large B-Cell Lymphoma,a Type of Blood CancerNCT01499303
Diffuse Large B...
Fostamatinib
18 Years - AstraZeneca
Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic MalignanciesNCT01796470
Chronic Lymphoc...
Mantle Cell Lym...
Diffuse Large B...
Indolent Non-Ho...
Entospletinib
Idelalisib
18 Years - Gilead Sciences
Dose-adjusted EPOCH-R in MYC Positive DLBCLNCT01914718
Diffuse Large B...
DA-EPOCH-R
18 Years - 70 YearsFudan University
Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic MalignanciesNCT01796470
Chronic Lymphoc...
Mantle Cell Lym...
Diffuse Large B...
Indolent Non-Ho...
Entospletinib
Idelalisib
18 Years - Gilead Sciences
CD19/22 CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell LymphomaNCT03287817
Diffuse Large B...
Relapsed Diffus...
Refractory Diff...
DLBCL
AUTO3
18 Years - Autolus Limited
A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Patients With B-cell Non-Hodgkin Lymphoma That Have Been Previously TreatedNCT03888105
B-cell Non-Hodg...
Odronextamab
18 Years - Regeneron Pharmaceuticals
Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapyNCT00790036
Diffuse Large B...
Everolimus
Everolimus Plac...
18 Years - Novartis
Diet, Physical Activity and Body Composition Changes During R-CHOPNCT04293900
Non-Hodgkin Lym...
DLBCL
Diffuse Large B...
24-hour dietary...
Hand grip stren...
International P...
Patient-reporte...
Pittsburgh Slee...
Functional Asse...
urine sample (o...
fecal sample (o...
18 Years - George Washington University
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