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Spots Global Cancer Trial Database for Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

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Trial Identification

Brief Title: Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Official Title: A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkin's Lymphoma

Study ID: NCT02793583

Study Description

Brief Summary: Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

Detailed Description: The purpose of this study is to evaluate the efficacy and safety of umbralisib monotherapy and the umbralisib + ublituximab (U2) combination in aggressive and indolent lymphomas and to also explore the U2 regimen in combination with bendamustine in the treatment of NHL (FL, SLL, MZL, DLBCL and MCL).

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

TG Therapeutics Investigational Trial Site, Birmingham, Alabama, United States

TG Therapeutics Investigational Trial Site, Huntsville, Alabama, United States

TG Therapeutics Investigational Trial Site, Chandler, Arizona, United States

TG Therapeutics Investigational Trial Site, Tucson, Arizona, United States

TG Therapeutics Investigational Trial Site, Tucson, Arizona, United States

TG Therapeutics Investigational Trial Site, Los Angeles, California, United States

TG Therapeutics Investigational Trial Site, Orange, California, United States

TG Therapeutics Investigational Trial Site, San Diego, California, United States

TG Therapeutics Investigational Trial Site, San Diego, California, United States

TG Therapeutics Investigational Trial Site, Whittier, California, United States

TG Therapeutics Investigational Trial Site, Aurora, Colorado, United States

TG Therapeutics Investigational Trial Site, Denver, Colorado, United States

TG Therapeutics Investigational Trial Site, Fort Collins, Colorado, United States

TG Therapeutics Investigational Trial Site, Bridgeport, Connecticut, United States

TG Therapeutics Investigational Trial Site, Newark, Delaware, United States

TG Therapeutics Investigational Trial Site, Washington, District of Columbia, United States

TG Therapeutics Investigational Trial Site, Boca Raton, Florida, United States

TG Therapeutics Investigational Trial Site, Fort Myers, Florida, United States

TG Therapeutics Investigational Trial Site, Gainesville, Florida, United States

TG Therapeutics Investigational Trial Site, Jacksonville, Florida, United States

TG Therapeutics Investigational Trial Site, Jacksonville, Florida, United States

TG Therapeutics Investigational Trial Site, Jacksonville, Florida, United States

TG Therapeutics Investigational Trial Site, Miami, Florida, United States

TG Therapeutics Investigational Trial Site, Saint Petersburg, Florida, United States

TG Therapeutics Investigational Trial Site, Tallahassee, Florida, United States

TG Therapeutics Investigational Trial Site, Tampa, Florida, United States

TG Therapeutics Investigational Trial Site, West Palm Beach, Florida, United States

TG Therapeutics Investigational Trial Site, Albany, Georgia, United States

TG Therapeutics Investigational Trial Site, Macon, Georgia, United States

TG Therapeutics Investigational Trial Site, Marietta, Georgia, United States

TG Therapeutics Investigational Trial Site, Chicago, Illinois, United States

TG Therapeutics Investigational Trial Site, Chicago, Illinois, United States

TG Therapeutics Investigational Trial Site, Decatur, Illinois, United States

TG Therapeutics Investigational Trial Site, Evanston, Illinois, United States

TG Therapeutics Investigational Trial Site, Harvey, Illinois, United States

TG Therapeutics Investigational Trial Site, Maywood, Illinois, United States

TG Therapeutics Investigational Trial Site, Niles, Illinois, United States

TG Therapeutics Investigational Trial Site, Peoria, Illinois, United States

TG Therapeutics Investigational Trial Site, Swansea, Illinois, United States

TG Therapeutics Investigational Trial Site, Fort Wayne, Indiana, United States

TG Therapeutics Investigational Trial Site, Indianapolis, Indiana, United States

TG Therapeutics Investigational Trial Site, Westwood, Kansas, United States

TG Therapeutics Investigational Trial Site, Louisville, Kentucky, United States

TG Therapeutics Investigational Trial Site, Covington, Louisiana, United States

TG Therapeutics Investigational Trial Site, Brewer, Maine, United States

TG Therapeutics Investigational Trial Site, Baltimore, Maryland, United States

TG Therapeutics Investigational Trial Site, Bethesda, Maryland, United States

TG Therapeutics Investigational Trial Site, Columbia, Maryland, United States

TG Therapeutics Investigational Trial Site, Towson, Maryland, United States

TG Therapeutics Investigational Trial Site, Ann Arbor, Michigan, United States

TG Therapeutics Investigational Trial Site, Duluth, Minnesota, United States

TG Therapeutics Investigational Trial Site, Saint Louis Park, Minnesota, United States

TG Therapeutics Investigational Trial Site, Columbia, Missouri, United States

TG Therapeutics Investigational Trial Site, Kansas City, Missouri, United States

TG Therapeutics Investigational Trial Site, Saint Louis, Missouri, United States

TG Therapeutics Investigational Trial Site, Billings, Montana, United States

TG Therapeutics Investigational Trial Site, Lincoln, Nebraska, United States

TG Therapeutics Investigational Trial Site, Omaha, Nebraska, United States

TG Therapeutics Investigational Trial Site, Lebanon, New Hampshire, United States

TG Therapeutics Investigational Trial Site, Hackensack, New Jersey, United States

TG Therapeutics Investigational Trial Site, Morristown, New Jersey, United States

TG Therapeutics Investigational Trial Site, Mount Holly, New Jersey, United States

TG Therapeutics Investigational Trial Site, Farmington, New Mexico, United States

TG Therapeutics Investigational Trial Site, Bronx, New York, United States

TG Therapeutics Investigational Trial Site, Buffalo, New York, United States

TG Therapeutics Investigational Trial Site, New York, New York, United States

TG Therapeutics Investigational Trial Site, Syracuse, New York, United States

TG Therapeutics Investigational Trial Site, Charlotte, North Carolina, United States

TG Therapeutics Investigational Trial Site, Durham, North Carolina, United States

TG Therapeutics Investigational Trial Site, Hickory, North Carolina, United States

TG Therapeutics Investigational Trial Site, Kinston, North Carolina, United States

TG Therapeutics Investigational Trial Site, Raleigh, North Carolina, United States

TG Therapeutics Investigational Trial Site, Washington, North Carolina, United States

TG Therapeutics Investigational Trial Site, Canton, Ohio, United States

TG Therapeutics Investigational Trial Site, Cincinnati, Ohio, United States

TG Therapeutics Investigational Trial Site, Cincinnati, Ohio, United States

TG Therapeutics Investigational Trial Site, Cleveland, Ohio, United States

TG Therapeutics Investigational Trial Site, Columbus, Ohio, United States

TG Therapeutics Investigational Trial Site, Toledo, Ohio, United States

TG Therapeutics Investigational Trial Site, Portland, Oregon, United States

TG Therapeutics Investigational Trial Site, Portland, Oregon, United States

TG Therapeutics Investigational Trial Site, Springfield, Oregon, United States

TG Therapeutics Investigational Trial Site, Camp Hill, Pennsylvania, United States

TG Therapeutics Investigational Trial Site, Philadelphia, Pennsylvania, United States

TG Therapeutics Investigational Trial Site, Providence, Rhode Island, United States

TG Therapeutics Investigational Trial Site, Greenville, South Carolina, United States

TG Therapeutics Investigational Trial Site, Sioux Falls, South Dakota, United States

TG Therapeutics Investigational Trial Site, Watertown, South Dakota, United States

TG Therapeutics Investigational Trial Site, Chattanooga, Tennessee, United States

TG Therapeutics Investigational Trial Site, Kingsport, Tennessee, United States

TG Therapeutics Investigational Trial Site, Knoxville, Tennessee, United States

TG Therapeutics Investigational Trial Site, Memphis, Tennessee, United States

TG Therapeutics Investigational Trial Site, Austin, Texas, United States

TG Therapeutics Investigational Trial Site, Dallas, Texas, United States

TG Therapeutics Investigational Trial Site, Fort Sam Houston, Texas, United States

TG Therapeutics Investigational Trial Site, Houston, Texas, United States

TG Therapeutics Investigational Trial Site, San Antonio, Texas, United States

TG Therapeutics Investigational Trial Site, San Antonio, Texas, United States

TG Therapeutics Investigational Trial Site, San Antonio, Texas, United States

TG Therapeutics Investigational Trial Site, Tyler, Texas, United States

TG Therapeutics Investigational Trial Site, Ogden, Utah, United States

TG Therapeutics Investigational Trial Site, Blacksburg, Virginia, United States

TG Therapeutics Investigational Trial Site, Newport News, Virginia, United States

TG Therapeutics Investigational Trial Site, Olympia, Washington, United States

TG Therapeutics Investigational Trial Site, Seattle, Washington, United States

TG Therapeutics Investigational Trial Site, Seattle, Washington, United States

TG Therapeutics Investigational Trial Site, Seattle, Washington, United States

TG Therapeutics Investigational Trial Site, Spokane, Washington, United States

TG Therapeutics Investigational Trial Site, Vancouver, Washington, United States

TG Therapeutics Investigational Trial Site, Madison, Wisconsin, United States

TG Therapeutics Investigational Trial Site, Wauwatosa, Wisconsin, United States

TG Therapeutics Investigational Trial Site, Gosford, New South Wales, Australia

TG Therapeutics Investigational Trial Site, Wahroonga, New South Wales, Australia

TG Therapeutics Investigational Trial Site, Benowa, Queensland, Australia

TG Therapeutics Investigational Trial Site, South Brisbane, Queensland, Australia

TG Therapeutics Investigational Trial Site, Adelaide, South Australia, Australia

TG Therapeutics Investigational Trial Site, Heidelberg, Victoria, Australia

TG Therapeutics Investigational Trial Site, Nedlands, Western Australia, Australia

TG Therapeutics Investigational Trial Site, Netherlands, Western Australia, Australia

TG Therapeutics Investigational Trial Site, Gosford, , Australia

TG Therapeutics Investigational Trial Site, Ashkelon, , Israel

TG Therapeutics Investigational Trial Site, Be'er Sheva, , Israel

TG Therapeutics Investigational Trial Site, Haifa, , Israel

TG Therapeutics Investigational Trial Site, Jerusalem, , Israel

TG Therapeutics Investigational Trial Site, Nahariya, , Israel

TG Therapeutics Investigational Trial Site, Petah Tikva, , Israel

TG Therapeutics Investigational Trial Site, Tel Aviv, , Israel

TG Therapeutics Investigational Trial Site, Tel Aviv, , Israel

TG Therapeutics Investigational Trial Site, Bologna, , Italy

TG Therapeutics Investigational Trial Site, Ferrara, , Italy

TG Therapeutics Investigational Trial Site, Milan, , Italy

TG Therapeutics Investigational Trial Site, Milan, , Italy

TG Therapeutics Investigational Trial Site, Rome, , Italy

TG Therapeutics Investigational Trial Site, Torino, , Italy

TG Therapeutics Investigational Trial Site, Busan, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Busan, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Gyeonggi-do, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Incheon, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Seoul, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Seoul, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Seoul, , Korea, Republic of

TG Therapeutics Investigational Trial Site, Chorz贸w, , Poland

TG Therapeutics Investigational Trial Site, Gdynia, , Poland

TG Therapeutics Investigational Trial Site, Krak贸w, , Poland

TG Therapeutics Investigational Trial Site, Lublin, , Poland

TG Therapeutics Investigational Trial Site, S艂upsk, , Poland

TG Therapeutics Investigational Trial Site, Warszawa, , Poland

TG Therapeutics Investigational Trial Site, Warszawa, , Poland

TG Therapeutics Investigational Trial Site, Wroc艂aw, , Poland

TG Therapeutics Investigational Trial Site, 艁贸d藕, , Poland

TG Therapeutics Investigational Trial Site, Bratislava, , Slovakia

TG Therapeutics Investigational Trial Site, Bratislava, , Slovakia

TG Therapeutics Investigational Trial Site, Ko拧ice, , Slovakia

TG Therapeutics Investigational Trial Site, Poprad, , Slovakia

TG Therapeutics Investigational Trial Site, Barcelona, , Spain

TG Therapeutics Investigational Trial Site, Barcelona, , Spain

TG Therapeutics Investigational Trial Site, Madrid, , Spain

TG Therapeutics Investigational Trial Site, Madrid, , Spain

TG Therapeutics Investigational Trial Site, Salisbury, , Spain

TG Therapeutics Investigational Trial Site, Valencia, , Spain

TG Therapeutics Investigational Trial Site, Cambridge, , United Kingdom

TG Therapeutics Investigational Trial Site, Denmark Hill, , United Kingdom

TG Therapeutics Investigational Trial Site, Leeds, , United Kingdom

TG Therapeutics Investigational Trial Site, Liverpool, , United Kingdom

TG Therapeutics Investigational Trial Site, London, , United Kingdom

TG Therapeutics Investigational Trial Site, London, , United Kingdom

TG Therapeutics Investigational Trial Site, Oxford, , United Kingdom

TG Therapeutics Investigational Trial Site, Plymouth, , United Kingdom

Contact Details

Name: Owen A O'Connor, MD, PhD

Affiliation: Columbia University

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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