Spots Global Cancer Trial Database for Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors

Official Title: Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors

Study ID: NCT04414020

Conditions

Diffuse Traumatic Cerebral Edema

Interventions

Progesteron

Study Description

Brief Summary: Neuronal injury is evident in elective craniotomy for space occupying lesions. Surgical trauma and mechanichal impact of the tumor causes neuronal injury. Neurosreroid progesterone is a neurotransmittern , trail to use in abolishing neurotoxcicty

Detailed Description: Progesterone is a natural neurosteroid that we are trying to use to impede both direct neuronal injury cauesd by and indirectly by surgical trauma. Progesterone can decreas vasogenic brain oedema. Our primary outcome is to ameliorate microscopic cytoplasmic injury and decrease brain oedema exploited by biopsy from brain tumor interface. Exclusion criteria demonstratd as refusal to participate in the trial , emergency craniotomy, recurrent brain tumor.