Spots Global Cancer Trial Database for Role of Genomic Imprinting in Cancer Diagnosis
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Trial Identification
Brief Title: Role of Genomic Imprinting in Cancer Diagnosis
Official Title: Role of Genomic Imprinting in Cancer Diagnosis
Study ID: NCT03882684
Interventions
Study Description
Brief Summary: The current research focus for cancer diagonosis is classical genetics, named "driving genes". However, not all cancer patients have typical genetic alterations, especially at early stage. In the past dacades, accumulating evidences have revealed that more than 80% diseases are closely related to epigenetic changes. The normally silenced copy of imprinted genes are reactivated at early stage of cancers, and finally proceed to copy number variation. This study will screen for a panel of imprinted genes and build quantitative models to assist the diagnosis of multiple cancers.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Zhongshan Hospital of Fudan University, Shanghai, Shanghai, China
Contact Details
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