Spots Global Cancer Trial Database for biomarker
Every month we try and update this database with for biomarker cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| The Clinical Outcome and the Exploration of Related Biomarkers of Target Therapy in Metastasis Colorectal Cancer | NCT02523495 | Neoplasms, Ther... | - | Huazhong University of Science and Technology | ||
| Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer | NCT01762813 | Colorectal Canc... | open and laparo... | 18 Years - | Helse Stavanger HF | |
| Role of Genomic Imprinting in Cancer Diagnosis | NCT03882684 | Early Diagnosis Cancer Biomarker Genomic Imprint... | In-situ imprint... | 18 Years - | Chinese Alliance Against Lung Cancer | |
| Localized Leiomyosarcoma Biomarker Protocol | NCT04925089 | Leiomyosarcoma | Blood and Tissu... | - | University of Michigan Rogel Cancer Center | |
| Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM) | NCT02997423 | Glioblastoma | 21 Years - | University of Iowa | ||
| Biomarker Discovery and Validation in Lung Cancer | NCT01147562 | Lung Cancer | Collection of b... | 18 Years - | Public Research Centre Health, Luxembourg | |
| Study Of AG-013736 (Axitinib) In Patients With Advanced Solid Tumors | NCT00447005 | Carcinoma | Axitinib (AG-01... | 20 Years - 75 Years | Pfizer | |
| The Clinical Outcome and the Exploration of Related Biomarkers of Target Therapy in Metastasis Colorectal Cancer | NCT02523495 | Neoplasms, Ther... | - | Huazhong University of Science and Technology | ||
| S100B in Intensive Care Patients With and Without Traumatic Brain Injury | NCT04501315 | Tumor Brain Injuries Trauma Injury Critical Illnes... Surgery--Compli... | Blood, cerebros... | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric Cancer | NCT03219593 | Gastric Cancer Apatinib Biomarker | Apatinib mesyla... | 65 Years - | First Affiliated Hospital Bengbu Medical College | |
| Prognostic Value of Biomarkers in HR + / HER2 - Advanced Breast Cancer | NCT04683770 | Breast Cancer | 18 Years - 80 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | ||
| Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC | NCT04405661 | NSCLC | 18 Years - 70 Years | Guangzhou Institute of Respiratory Disease | ||
| Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions | NCT06267703 | Chronic Atrophi... | Metabolomic pro... | 46 Years - 97 Years | Karolinska Institutet | |
| AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer. | NCT02102165 | Metastatic Brea... | metastatic lesi... | 18 Years - | Breast International Group | |
| Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer | NCT03532711 | Metastatic Colo... Chemotherapy Ef... Biomarker | fluorouracil | 18 Years - 80 Years | Fudan University | |
| Serial Plasma EBV DNA for Nasopharyngeal Carcinoma | NCT02476669 | Nasopharyngeal ... | - | The University of Hong Kong | ||
| Melanoma Biomarker Study | NCT00348088 | Metastatic Mela... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | ||
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| Circulating Tumor DNA as Surgical Biomarker in Patients With PancrEatic Adenocarcinoma for Statement of Resectability | NCT05853198 | PDAC - Pancreat... | ctDNA analysis | 18 Years - | Azienda Ospedaliera Universitaria Integrata Verona | |
| The Occurence of Pancreatic Cancer Studied in Association With Newly Diagnosed Diabetes in the Elderly | NCT04164602 | Diabetes Mellit... Diabetes Diabetes Mellit... Diabetes type2 Cancer of Pancr... Pancreas Neopla... Pancreas Adenoc... Pancreatic Canc... | 60 Years - | University of Pecs | ||
| MRI and Biomarkers in Prostate Cancer | NCT02241122 | Prostate Cancer | prostate biopsy | 18 Years - 85 Years | Turku University Hospital | |
| De-escalation Study for Stage IIa/IIb < 3 cm Seminoma | NCT05529251 | Seminoma Stage II | Radiotherapy bo... Carboplatin AUC... 3 cycles of EP | 18 Years - | Centre Leon Berard | |
| A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC | NCT04959981 | Advanced Non-sq... | ERAS-007 ERAS-601 Osimertinib Sotorasib | 18 Years - 99 Years | Erasca, Inc. | |
| Biomarker for Patients With Fabry Disease (BioFabry) | NCT02778295 | Angiokeratomas Chronic Kidney ... Ocular Abnormal... Hearing Loss | 2 Months - | CENTOGENE GmbH Rostock | ||
| Serum Dickkopf-4 as a Biomarker for the Diagnosis and Treatment of Gastrointestinal Stromal Tumor | NCT02931981 | Gastrointestina... | surgery or biop... | 18 Years - 70 Years | RenJi Hospital | |
| Application of Serum Bile Acid Profile in the Diagnosis of Gastric Cancer | NCT06031779 | Gastric Cancer | 18 Years - 75 Years | Xijing Hospital of Digestive Diseases | ||
| Biomarker Study of Pts With Metastatic ccRCC Undergoing Sequential Therapy With 1st Line Sunitinib and 2nd Line Axitinib | NCT03592199 | Clear Cell Rena... | Sunitinib | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods | NCT05501353 | Colorectal Canc... | no intervention | 18 Years - 99 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening. | NCT06016569 | Lung Cancer | Exhaled breath ... Blood sampling LDCT Vital signs Spirometry | 55 Years - 74 Years | The Institute of Molecular and Translational Medicine, Czech Republic | |
| Chemotherapy Intensification in Patients With High Lactate Dehydrogenase Values and Soluble Syndecan1 Levels | NCT03117972 | Metastatic Colo... | FOLFOXIRI FOLFOX FOLFIRI Bevacizumab LV5FU2 Capecitabine | 18 Years - 76 Years | Centre Hospitalier Universitaire de Besancon | |
| Developing Circulating and Imaging Biomarkers Towards Personalised Radiotherapy in Lung Cancer | NCT06086574 | Lung Cancer Sta... | 18 Years - | University of Manchester | ||
| Prognostic and Predictive Value of HE4 Biomarker in Metastatic Ovarian Cancer | NCT01768156 | Metastatic Ovar... | Experimental ar... | 18 Years - | Institut du Cancer de Montpellier - Val d'Aurelle | |
| Biomarker Study of Pts With Metastatic ccRCC Undergoing Sequential Therapy With 1st Line Sunitinib and 2nd Line Axitinib | NCT03592199 | Clear Cell Rena... | Sunitinib | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| Biomarker for Hyaline Fibromatosis Syndrome (BioHFS) | NCT03196115 | Hyalinosis Hyaline Membran... Juvenile Hyalin... Fibromatosis Hy... Skin and Connec... | 2 Months - | CENTOGENE GmbH Rostock | ||
| An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin | NCT01816659 | Colorectal Carc... | Metformin ER | 18 Years - 75 Years | M.D. Anderson Cancer Center | |
| Open Label, Single Arm Trial to Characterize Patients With Metastatic RCC Treated With Everolimus After Failure of the First VEGF-targeted Therapy (MARC-2) | NCT01266837 | Metastatic Rena... Failure of Exac... | Everolimus | 18 Years - | iOMEDICO AG | |
| Cell-free DNA From Junction of Hepatitis B Virus Integration in HCC Patients for Monitoring Post-resection Recurrence | NCT05823584 | Hepatocellular ... | 20 Years - | TCM Biotech International Corp. | ||
| Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer | NCT04642664 | Biliary Tract C... Cholangiocarcin... Biomarker Hepatobiliary N... | Apatinib plus C... | 18 Years - | Peking Union Medical College Hospital | |
| Radiotherapy and Androgen Deprivation In Combination After Local Surgery (RADICALS) Translational Study | NCT06145958 | Prostate Cancer | Luteinising Hor... | 18 Years - 99 Years | University College, London | |
| Individualizing Pazopanib Therapy by exploRing the Role of Early Metabolic responsE and Drug Exposure as a preDICTor for Treatment Outcome in Patients With STS | NCT01995981 | Sarcoma, Soft T... | Pazopanib | 18 Years - | Radboud University Medical Center | |
| A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC | NCT04959981 | Advanced Non-sq... | ERAS-007 ERAS-601 Osimertinib Sotorasib | 18 Years - 99 Years | Erasca, Inc. | |
| MRI and Metabolomics Biomarkers for Uterine Malignancy | NCT02528864 | Uterine Neoplas... | 20 Years - 80 Years | Chang Gung Memorial Hospital | ||
| Biomarkers in Primary Sjögren's Syndrome | NCT03765593 | Primary Sjögren... Lymphoma, Non-H... | Biopsy Salivary... | 18 Years - | National Council of Scientific and Technical Research, Argentina | |
| Serial Plasma EBV DNA for Nasopharyngeal Carcinoma | NCT02476669 | Nasopharyngeal ... | - | The University of Hong Kong | ||
| Prognostic and Predictive Impact of Circulating Tumor DNA in Gastric Cancer Treatment | NCT02674373 | Gastric Cancer | 18 Years - | Association des Gastroentérologues Oncologues | ||
| 89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors | NCT01338090 | Neuroendocrine ... | 89Zr-bevacizuma... Everolimus | 18 Years - 80 Years | University Medical Center Groningen | |
| An Epidemiological Study of Genetic Risk Factors for Prostate Cancer in African-American and Caucasian Males | NCT00342771 | Prostate Cancer | 40 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Samsung Medical Center-Lymphoma Cohort Study-II | NCT01877109 | Lymphoma | 19 Years - | Samsung Medical Center | ||
| Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer | NCT06307938 | Colorectal Canc... Colorectal Aden... | liquid biopsy | 18 Years - | Helse Nord-Trøndelag HF | |
| miRNA and Relevant Biomarkers of BC Patients Undergoing Neoadjuvant Treatment | NCT03779022 | Breast Cancer | microRNA | 18 Years - 75 Years | Peking University First Hospital | |
| Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial | NCT01995942 | Adenocarcinoma Rectal Diseases Colorectal Neop... Adenocarcinoma,... Carcinoma Neoplasms, Glan... Neoplasms by Hi... Neoplasms Neoplasms, Cyst... Intestinal Neop... Gastrointestina... Digestive Syste... Neoplasms by Si... Digestive Syste... Gastrointestina... Intestinal Dise... | 18 Years - | Royal Marsden NHS Foundation Trust | ||
| Circulating MicroRNA as Biomarker of Cardiotoxicity in Breast Cancer | NCT02065908 | Breast Cancer | 18 Years - 70 Years | West Pomeranian Cancer Center | ||
| Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting | NCT05826756 | Lung Cancer Pat... Caregivers | There are no in... | 18 Years - | LUNGevity Foundation | |
| ReIMAGINE Prostate Cancer Risk | NCT04060589 | Prostate Cancer | Tissue donation Blood Donation Urine Donation Healthcare data... | 18 Years - 90 Years | University College, London | |
| Liquid Biopsy for Early Non-small Lung Cancer Detection | NCT05462795 | Non Small-cell ... | Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... | 18 Years - | University of Arizona | |
| A Retrospective Analysis of Magnetic Resonance Imaging Data for Breast Cancer Screening in the Open Consortium for Decentralized Medical Artificial Intelligence | NCT05698056 | Breast Cancer | No intervention... | 18 Years - 90 Years | Technische Universität Dresden | |
| Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma | NCT01473095 | Solid Tumor Malignant Lymph... Tumor | ARQ 092 | 18 Years - | ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) | |
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| 89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors | NCT01338090 | Neuroendocrine ... | 89Zr-bevacizuma... Everolimus | 18 Years - 80 Years | University Medical Center Groningen | |
| CASUS: Validation for Detection of Precursor Lesions | NCT04530201 | Cervical Cancer Cervical Intrae... Human Papilloma... HPV-Related Cer... Urine | Colli-Pee Small... | 25 Years - 64 Years | Universiteit Antwerpen | |
| A Longitudinal, Observational Biomarker Study in Pancreatic Cancer Patients Receiving Chemotherapy | NCT04281511 | Pancreatic Canc... | - | National Cancer Center, Korea | ||
| Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA | NCT05375370 | Hepatocellular ... | circulating tum... | 18 Years - | University Hospital, Rouen | |
| Intestinal Flora Sequencing for Nasopharyngeal Carcinoma | NCT04094545 | Nasopharyngeal ... | 18 Years - 75 Years | The Third Xiangya Hospital of Central South University | ||
| Single-Cell Map of Immune and Lymphoma Cells in B-cell Non-Hodgkin's Lymphoma | NCT04696692 | Diffuse Large B... | Patient with hi... | 18 Years - 80 Years | Institut Claudius Regaud | |
| Detection of Clinically Significant Prostate Cancer Using a Urinary Multimarker Sensor | NCT04825002 | Prostate Cancer | Urinary multima... | 50 Years - 80 Years | Asan Medical Center | |
| Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients | NCT05637216 | Radiation Induc... | Losartan 25 mil... Placebo | 18 Years - | Shaw Cancer Center | |
| Tumor Vaccines for Solid Tumors | NCT06102837 | Glioma Solid Tumor | tumor vaccine Radiotherapy Chemotherapy Surgery | - | Huashan Hospital | |
| Individualizing Pazopanib Therapy by exploRing the Role of Early Metabolic responsE and Drug Exposure as a preDICTor for Treatment Outcome in Patients With STS | NCT01995981 | Sarcoma, Soft T... | Pazopanib | 18 Years - | Radboud University Medical Center | |
| Detecting Lung Cancer Based on Exhaled Breath | NCT04419207 | Carcinoma Lung Cancer NSCLC Lung Neoplasms | Breath test | 18 Years - | Peking University People's Hospital | |
| Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease | NCT00970970 | Von Hippel-Lind... Hemangioblastom... Renal Cell Carc... Pheochromocytom... Pancreatic Neur... | 89Zr bevacizuma... | 18 Years - | University Medical Center Groningen | |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy | NCT01847001 | Locally Advance... Breast Cancer | Propranolol DOT imaging Paclitaxel Nab-paclitaxel Trastuzumab Pertuzumab Doxorubicin Cyclophosphamid... Surgery Premedication Anti-nausea the... Pegfilgrastim | 18 Years - | Columbia University | |
| Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions | NCT06267703 | Chronic Atrophi... | Metabolomic pro... | 46 Years - 97 Years | Karolinska Institutet | |
| Plasma and Tissue SAA1 Levels in Cancer Patients to Predict Hyperprogression of Immunotherapy | NCT06276088 | Immunotherapy Hyperprogressio... Biomarker | 18 Years - | Nanfang Hospital, Southern Medical University | ||
| Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-Oncology | NCT04264975 | Solid Carcinoma | fecal microbiot... | 19 Years - | Asan Medical Center | |
| Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay | NCT00696345 | Colorectal Canc... | 40 Years - | Epigenomics, Inc | ||
| Prospective Evaluation of Immunological, Molecular-genetic, Image-based and Microbial Analyzes to Characterize Tumor Response and Control in Patients With Inoperable Stage III NSCLC Treated With Chemoradiotherapy Followed by Consolidation Therapy With Durvalumab | NCT05027165 | Oncology Biomarker NSCLC, Stage II... Durvalumab Chemoradiothera... | Non-interventio... | 18 Years - | LMU Klinikum | |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy | NCT01847001 | Locally Advance... Breast Cancer | Propranolol DOT imaging Paclitaxel Nab-paclitaxel Trastuzumab Pertuzumab Doxorubicin Cyclophosphamid... Surgery Premedication Anti-nausea the... Pegfilgrastim | 18 Years - | Columbia University | |
| Comparison of Healthy Diets on Breast Cancer Markers | NCT02744079 | Breast Neoplasm... | Low carbohydrat... Low fat diet | 21 Years - | Albert Einstein College of Medicine | |
| MyProstateScore Equivalency With and Without DRE | NCT05700370 | Prostate Cancer | MyProstateScore | 45 Years - | LynxDx | |
| Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers | NCT04211168 | Advanced Biliar... | Toripalimab plu... | 18 Years - | Peking Union Medical College Hospital |
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