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Spots Global Cancer Trial Database for A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

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Trial Identification

Brief Title: A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Official Title: A Phase 2, Randomized, Active-Controlled, Open-Label Study to Evaluate the Efficacy and Safety of LBL-007 in Combination With Tislelizumab Plus Chemotherapy as First-Line Treatment in Patients With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Study ID: NCT06010303

Study Description

Brief Summary: This is a randomized, open-label study to compare how well LBL-007 works in combination with tislelizumab and chemotherapy versus tislelizumab and chemotherapy when given as the first-line treatment in participants with inoperable locally advanced or metastatic esophageal squamous cell carcinoma (ESCC).

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Anhui Provincial Hospital, Hefei, Anhui, China

The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

Peking Union Medical College Hospital, Beijing, Beijing, China

Fujian Medical University Union Hospital, Fuzhou, Fujian, China

Fujian Cancer Hospital, Fuzhou, Fujian, China

Lanzhou University Second Hospital, Lanzhou, Gansu, China

The Tumor Hospital Affiliated to Guangxi Medical University, Nanning, Guangxi, China

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China

Anyang Cancer Hospital, Anyang, Henan, China

Nanyang Central Hospital, Nanyang, Henan, China

The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China

Henan Cancer Hospital, Zhengzhou, Henan, China

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Hunan Cancer Hospital, Changsha, Hunan, China

The First Peoples Hospital of Changzhou, Changzhou, Jiangsu, China

Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China

Nantong Tumor Hospital Branch North, Nantong, Jiangsu, China

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

Shandong Cancer Hospital, Jinan, Shandong, China

The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, China

Sichuan Cancer Hospital and Institute, Chengdu, Sichuan, China

Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital, Chengdu, Sichuan, China

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

National Cancer Center, Goyangsi, Gyeonggido, Korea, Republic of

Gachon University Gil Medical Center, Incheon, Incheon Gwang'yeogsi, Korea, Republic of

Chonnam National University Hwasun Hospital, Hwasungun, Jeonranamdo, Korea, Republic of

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi, Korea, Republic of

Severance Hospital Yonsei University Health System, Seoul, Seoul Teugbyeolsi, Korea, Republic of

Asan Medical Center, Seoul, Seoul Teugbyeolsi, Korea, Republic of

The Catholic University of Korea, Seoul St Marys Hospital, Seoul, Seoul Teugbyeolsi, Korea, Republic of

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi, Korea, Republic of

Changhua Christian Hospital, Changhua, , Taiwan

Kaohsiung Medical University Chung Ho Memorial Hospital, Kaohsiung, , Taiwan

China Medical University Hospital, Taichung, , Taiwan

National Taiwan University Hospital, Taipei, , Taiwan

Taipei Veterans General Hospital, Taipei, , Taiwan

Ramathibodi Hospital Mahidol University, Bangkok, , Thailand

Siriraj Hospital, Bangkok, , Thailand

Songklanagarind Hospital (Prince of Songkhla University), Hat Yai, , Thailand

Hrh Princess Maha Chakri Sirindhorn Medical Center (Srinakharinwirot University), Ongkharak, , Thailand

Phramongkutklao Hospital, Ratchathewi, , Thailand

Contact Details

Name: Study Director

Affiliation: BeiGene

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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