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Brief Title: Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma
Official Title: Phase Ib, Open-label, Single-arm, Multicenter Study to Evaluate Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma Progressed Following Treatment With Taxane/Platinum/Fluorouracil
Study ID: NCT03817567
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of recombinant anti-EGFR monoclonal antibody(SCT200)in patients with advanced esophageal squamous cell carcinoma progressed following treatment with taxane/platinum/fluorouracil.
Detailed Description: This is a open label, single-arm multicenter phase Ib study,and is designed to evaluate Objective Response Rate (ORR) in advanced esophageal squamous cell carcinoma progressed following treatment with taxane/platinum/fluorouracil treated with anti-EGFR monoclonal antibody SCT200.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Henan Cancer Hospital., Zhengzhou, Henan, China
The First Hospital of Jilin University, Changchun, Jilin, China
Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China