Spots Global Cancer Trial Database for esophageal neoplasms
Every month we try and update this database with for esophageal neoplasms cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Phase I Platinum Based Chemotherapy Plus Indomethacin | NCT01719926 | Colorectal Neop... Esophageal Neop... Ovarian Neoplas... | Indomethacin | 18 Years - | UMC Utrecht | |
| A Trial of CMNa Combined With Concurrent Chemoradiotherapy for Locally Recurrent ESCC | NCT02721576 | Esophageal Neop... | Sodium Glycidid... | 18 Years - 75 Years | Shandong Cancer Hospital and Institute | |
| Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction | NCT03549494 | Stomach Neoplas... Gastrointestina... Digestive Syste... Esophageal Neop... Head and Neck N... Gastrointestina... Digestive Syste... Esophageal Dise... Stomach Disease... Esophagogastric... | Ocoxin-Viusid® | 18 Years - | Catalysis SL | |
| First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)-China Extension Study | NCT03881111 | Esophageal Neop... | Pembrolizumab Placebo Cisplatin 5-FU | 18 Years - | Merck Sharp & Dohme LLC | |
| Report of the Survival Outcomes of Patients With Esophageal Cancer After Definitive Radiotherapy in China | NCT05194371 | Esophageal Neop... | definitive radi... | 18 Years - | ChineseAMS | |
| Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma | NCT02908204 | Esophageal Neop... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | ||
| Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma | NCT00413075 | Solid Tumor Lymphoma | oral belinostat | 18 Years - | Valerio Therapeutics | |
| Simultaneous Integrated Boost Radiotherapy and Concurrent Nimotuzumab or Chemotherapy for Esophageal Carcinoma | NCT02858206 | Esophageal Neop... | IMRT simultaneo... Nimotuzumab Paclitaxel Nedaplatin Esophagectomy | 18 Years - 69 Years | ChineseAMS | |
| RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus | NCT00559351 | Esophageal Neop... Squamous Cell C... | transthoracic e... neoadjuvant che... neoadjuvant che... | 18 Years - 75 Years | Ministry of Scientific Research and Information Technology, Poland | |
| Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI | NCT04136236 | Esophageal Neop... Artificial Inte... Confocal Laser ... | The diagnosis o... | 18 Years - 80 Years | Shandong University | |
| Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma | NCT02908204 | Esophageal Neop... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | ||
| Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016) | NCT04976634 | Carcinoma, Hepa... Colorectal Neop... Pancreatic Duct... Biliary Tract N... Endometrial Neo... Esophageal Neop... | Pembrolizumab Belzutifan Lenvatinib | 18 Years - | Merck Sharp & Dohme LLC | |
| Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE | NCT02418052 | Esophageal Neop... Esophagectomy Anastomotic Lea... | neck flexion | 18 Years - 75 Years | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | |
| A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1 | NCT04908111 | Non-small Cell ... Esophageal Neop... | ChAdOx1-MAGEA3-... MVA-MAGEA3 Standard of car... MVA-NYESO | 18 Years - | Cancer Research UK | |
| Health and Employment After Gastro Intestinal Surgery - HEAGIS2 | NCT04466631 | Esophageal Neop... Gastric Neoplas... Colon Neoplasms | 18 Years - | University of Padova | ||
| Endoscopic Resection Multicenter Registry | NCT03065257 | Gastrointestina... Gastrointestina... Gastric Cancer Gastric Neoplas... Gastric Polyp Esophageal Neop... Duodenal Neopla... Duodenal Polyp Stomach Neoplas... Stomach Polyp Neoplasms Colon Polyp Colon Neoplasm | Endoscopic Rese... | 18 Years - | Weill Medical College of Cornell University | |
| A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors | NCT03261947 | Metastatic Panc... Colorectal Canc... Esophageal Neop... Carcinoma, Non-... | TAK-931 | 18 Years - | Takeda | |
| Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarkers | NCT05688176 | Esophageal Neop... | 18 Years - | University Hospital, Ghent | ||
| The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery | NCT02381249 | Esophageal Neop... Stomach Neoplas... Weight Loss Malnutrition Pancreatic Neop... Duodenal Neopla... | Octreotide Placebo | 18 Years - 100 Years | St. James's Hospital, Ireland | |
| Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors | NCT00413322 | Tumor | belinostat 5-Fluorouracil ... | 18 Years - | Valerio Therapeutics | |
| Lifting of Gastric Tube Through Trans-substernal Versus Trans-esophageal Bed Path in MIE | NCT02309619 | Esophageal Neop... Esophagectomy | lifting of the ... | 18 Years - 75 Years | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | |
| PD-1 Inhibitor Plus Chemotherapy With or Without Radiotherapy in Patients With Metastatic Esophageal Cancer | NCT06086457 | Esophageal Neop... | Radiation TP or PF regime... PD-1 inhibitor | 18 Years - | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Health and Employment After Gastro Intestinal Surgery - HEAGIS1 | NCT04466592 | Esophageal Neop... Stomach Neoplas... Colonic Neoplas... | Promotion of co... | 18 Years - | University of Padova | |
| Mediastinoscopy-assisted Transhiatal Esophagectomy Versus Thoraco-laparoscopic Esophagectomy for Esophageal Cancer | NCT04125849 | Esophageal Neop... | Thoraco-laparos... Mediastinoscopy... | 18 Years - 80 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus | NCT01572987 | Barrett's Esoph... Esophageal Neop... | Radiofrequency ... Endoscopic muco... | 18 Years - | Midwest Veterans' Biomedical Research Foundation | |
| Thromboprophylaxis in Oesophageal Cancer Patients | NCT05067153 | Esophageal Neop... Thrombosis Thromboembolism | Fragmin 5000 UN... | 18 Years - | University of Aarhus | |
| Removal of the Evolution® Esophageal Stent - Fully Covered | NCT01900691 | Esophageal Fist... Esophageal Neop... Esophageal Perf... Esophageal Sten... Stents | Evolution® Esop... | 18 Years - | Cook Group Incorporated | |
| Endoscopic Injection of Mitomycin C for the Treatment of Pharyngoesophageal Stenosis | NCT03540953 | Esophageal Sten... Deglutition Dis... Head and Neck N... Esophageal Neop... | Endoscopic inje... | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer | NCT00760604 | Esophageal Neop... | Esophagectomy | 18 Years - 85 Years | Weill Medical College of Cornell University | |
| A Study of Amivantamab in Participants With Previously Treated Advanced or Metastatic Gastric or Esophageal Cancer | NCT04945733 | Stomach Neoplas... Esophageal Neop... | Amivantamab | 20 Years - | Janssen Pharmaceutical K.K. | |
| Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer | NCT03474341 | Esophageal Canc... Esophageal Aden... Esophageal Squa... Esophageal Neop... | MRI PET-CT Endoscopy Blood samples | 18 Years - | UMC Utrecht | |
| Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer. | NCT05624099 | Esophageal Neop... Esophageal Dise... Digestive Syste... | camrelizumab Paclitaxel drug... Platinum drug Radiation | 18 Years - 75 Years | Fujian Cancer Hospital | |
| Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma | NCT02446574 | Esophageal Neop... | Paclitaxel Cisplatin Radiation | 18 Years - 68 Years | ChineseAMS | |
| The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy | NCT02604615 | Stage III Esoph... Esophageal Neop... | Capecitabine(Ai... Oxaliplatin(Aih... Radiotherapy | 45 Years - 75 Years | The First Affiliated Hospital of Henan University of Science and Technology | |
| Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma | NCT00413075 | Solid Tumor Lymphoma | oral belinostat | 18 Years - | Valerio Therapeutics | |
| Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer | NCT01928290 | Stomach Neoplas... Esophageal Neop... | Irinotecan Trastuzumab Oxaliplatin Leucovorin Fluorouracil | 18 Years - | Washington University School of Medicine | |
| Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus. | NCT06070376 | Esophageal Neop... Dysphagia | Fully Covered E... Partially Cover... | 18 Years - | Instituto do Cancer do Estado de São Paulo | |
| Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell Carcinoma | NCT03274011 | Esophageal Neop... | Apatinib | 18 Years - | Fudan University | |
| Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surgery | NCT04189393 | Gastrointestina... Colorectal Canc... Pancreatic Canc... Esophageal Canc... Rectum Neoplasm Esophageal Neop... Pancreatic Duct... Colonic Neoplas... Gastrointestina... Microbiota Anastomotic Lea... | 18 Years - | Radboud University Medical Center | ||
| TreatmENT of AnastomotiC Leakage After Esophagectomy | NCT03829098 | Esophageal Canc... Esophageal Neop... | Intervantions f... | 18 Years - | Radboud University Medical Center | |
| Health and Employment After Gastro Intestinal Surgery - HEAGIS1 | NCT04466592 | Esophageal Neop... Stomach Neoplas... Colonic Neoplas... | Promotion of co... | 18 Years - | University of Padova | |
| Mayo Clinic Upper Digestive Disease Survey | NCT02530983 | Esophageal Neop... Cancer of Esoph... Cancer of the E... Esophageal Canc... Esophagus Cance... Neoplasm, Esoph... Esophagectomy Abnormalities, ... Digestive Syste... | Mayo Clinic Upp... Upper Digestive... | 18 Years - | Mayo Clinic | |
| A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer | NCT02182804 | Esophageal Neop... | Olympus Cellvizio | 20 Years - | King Chulalongkorn Memorial Hospital | |
| A Study of SGN-STNV in Advanced Solid Tumors | NCT04665921 | Carcinoma, Non-... HER2 Negative B... Ovarian Neoplas... Uterine Cervica... Endometrial Neo... Esophageal Neop... Gastroesophagea... Stomach Neoplas... Colorectal Neop... Exocrine Pancre... Appendiceal Ade... Pseudomyxoma Pe... | SGN-STNV | 18 Years - | Seagen Inc. | |
| Home Jejunostomy Feeding Following Esophagectomy/Gastrectomy | NCT01870817 | Esophageal Neop... | Home jejunostom... | 18 Years - | University Hospitals, Leicester | |
| Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction Adenocarcinoma | NCT00813072 | Stomach Neoplas... Esophageal Neop... | PEP02 irinotecan docetaxel | 18 Years - | PharmaEngine | |
| TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cancer. | NCT05013697 | Esophageal Neop... | Paclitaxel + Ci... Paclitaxel + Ci... | 18 Years - 75 Years | Henan Cancer Hospital | |
| Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI | NCT04136236 | Esophageal Neop... Artificial Inte... Confocal Laser ... | The diagnosis o... | 18 Years - 80 Years | Shandong University | |
| Neoadjuvant Chemotherapy Followed by Preoperative Chemoradiation in Resectable Squamous-cell Esophageal Cancer | NCT03579004 | Esophageal Neop... Squamous Cell C... Concurrent Chem... | Paclitaxel Cisplatin Fluorouracil chemoradiothera... Ivor Lewis esop... | 18 Years - 75 Years | Russian Academy of Medical Sciences | |
| Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer | NCT04018872 | Esophagus Adeno... Esophagus Squam... Gastroesophagea... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer | NCT03474341 | Esophageal Canc... Esophageal Aden... Esophageal Squa... Esophageal Neop... | MRI PET-CT Endoscopy Blood samples | 18 Years - | UMC Utrecht | |
| A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC | NCT02721550 | Esophageal Neop... | Sodium Glycidid... | 18 Years - 75 Years | Shandong Cancer Hospital and Institute | |
| Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer | NCT05297734 | End of Life Cancer | Receive technol... Receive redesig... | 21 Years - | Stanford University | |
| Regorafenib in Combination With Paclitaxel in Advanced Oesophagogastric Carcinoma | NCT02406170 | Esophageal Neop... Stomach Neoplas... Neoplasm Metast... | Regorafenib Paclitaxel | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial | NCT00907543 | Esophageal Neop... | Preoperative tr... Postoperative t... | 18 Years - | Lawson Health Research Institute | |
| A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC | NCT02721550 | Esophageal Neop... | Sodium Glycidid... | 18 Years - 75 Years | Shandong Cancer Hospital and Institute | |
| Endoscopic Submucosal Dissection in Upper Gastrointestinal Canal With HybridKnife | NCT01185483 | Endoscopy, Dige... Esophageal Neop... Stomach Neoplas... | 18 Years - 85 Years | Odense University Hospital | ||
| A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer | NCT02182804 | Esophageal Neop... | Olympus Cellvizio | 20 Years - | King Chulalongkorn Memorial Hospital | |
| A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab | NCT02013154 | Esophageal Neop... Adenocarcinoma ... Gastroesophagea... Squamous Cell C... Gastric Adenoca... | DKN-01 150 mg Paclitaxel Pembrolizumab DKN-01 300 mg | 18 Years - | Leap Therapeutics, Inc. | |
| Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma | NCT02908204 | Esophageal Neop... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | ||
| A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer | NCT00760604 | Esophageal Neop... | Esophagectomy | 18 Years - 85 Years | Weill Medical College of Cornell University | |
| Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer | NCT02385617 | Esophageal Neop... Stomach Neoplas... Weight Loss Malnutrition | Octreotide Placebo | 18 Years - 100 Years | St. James's Hospital, Ireland | |
| Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer | NCT00368329 | Esophageal Neop... Carcinoma, Squa... Adenocarcinoma Esophageal Canc... | Capecitabine (X... [18-F] Fluorode... 5-Fluorouracil ... Carboplatin | 18 Years - | Stanford University | |
| Cardiopulmonary Effects of Intrathoracic Pressure Overshoot During Carbon Dioxide Insufflation in Thoracoscopic Surgery | NCT02330536 | Esophageal Neop... | Insufflation of... | 20 Years - 80 Years | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | |
| Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer | NCT03153280 | Colorectal Neop... Stomach Neoplas... Esophageal Neop... | Lithium Oxaliplatin Capecitabine | 18 Years - | Cancer Trials Ireland | |
| Tumor Hypoxia With HX4 PET in Several Diseases | NCT02584400 | Prostatic Neopl... Esophageal Neop... Neoplasm Metast... Rectal Neoplasm... Brain Neoplasm,... | Injection with ... | 18 Years - | Maastricht Radiation Oncology | |
| Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer | NCT00321958 | Barrett Esophag... Esophageal Neop... Deglutition Dis... GERD Neoplasm | CSA System (Cry... CryoSpray Ablat... | 18 Years - | University of Maryland, Baltimore | |
| Docetaxel and S-1 for Advanced Esophageal Cancer | NCT01693432 | Esophageal Neop... | DS (docetaxel+S... | 18 Years - | Hallym University Medical Center | |
| A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer | NCT02182804 | Esophageal Neop... | Olympus Cellvizio | 20 Years - | King Chulalongkorn Memorial Hospital | |
| PET-CT Based Radiotherapy in Esophageal Cancer Patients | NCT01156831 | Esophageal Neop... | 18 Years - | Maastricht Radiation Oncology | ||
| Comparison of Ivor Lewis and Tri-incision Approaches for Patients With Esophageal Cancer | NCT02017002 | Surgical Proced... Minimally Invas... Operative Esophageal Neop... Cancer of Esoph... Esophagectomy | Ivor Lewis Tri-incision | 20 Years - 75 Years | National Taiwan University Hospital | |
| A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection | NCT04510285 | Esophagogastric... Gastric Cancer Gastric Tumor Esophageal Canc... Esophageal Neop... Esophageal Tumo... GastroEsophagea... Gastroesophagea... Gastroesophagea... Gastroesophagea... | Trastuzumab Pembrolizumab | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Tezacitabine With or Without 5-Fluorouracil (5-FU) for Advanced Esophageal Cancer or Gastric Cancer | NCT00054873 | Esophageal Neop... Stomach Neoplas... Adenocarcinoma | tezacitabine 5-fluorouracil | 18 Years - | Chiron Corporation | |
| Effect of NST Whole-course Nutritional Management on Nutritional Status and Adverse Reactions in Esophageal Cancer | NCT05800054 | Esophageal Neop... Adverse Drug Ev... | Nutritional Sup... Docetaxel cisplatin Radiotherapy | 18 Years - 75 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer | NCT00368329 | Esophageal Neop... Carcinoma, Squa... Adenocarcinoma Esophageal Canc... | Capecitabine (X... [18-F] Fluorode... 5-Fluorouracil ... Carboplatin | 18 Years - | Stanford University | |
| Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors | NCT00413322 | Tumor | belinostat 5-Fluorouracil ... | 18 Years - | Valerio Therapeutics | |
| Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors | NCT00413322 | Tumor | belinostat 5-Fluorouracil ... | 18 Years - | Valerio Therapeutics | |
| Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer | NCT02128243 | Unresectable, L... Gastric Neoplas... Gastroesophagea... Esophageal Aden... Gastric Adenoca... Esophageal Neop... | S-1 de-escalati... Chemotherapy by... | 18 Years - | AIO-Studien-gGmbH | |
| A Study of Amivantamab in Participants With Previously Treated Advanced or Metastatic Gastric or Esophageal Cancer | NCT04945733 | Stomach Neoplas... Esophageal Neop... | Amivantamab | 20 Years - | Janssen Pharmaceutical K.K. | |
| Safety Study on the Transfer of the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma | NCT00328887 | Esophageal Neop... | CD40 Gene Trans... | 18 Years - 75 Years | Weill Medical College of Cornell University |
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