Spots Global Cancer Trial Database for Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
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Trial Identification
Brief Title: Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
Official Title: China Health Promotion Foundation/the Second Affiliated Hospital of Zhejiang University, School of Medicine
Study ID: NCT04989153
Interventions
Study Description
Brief Summary: Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors. To examine the diagnostic value of PG levels and Helicobacter pylori (Hp) status for GC and precancerous lesions screening in asymptomatic individuals undergoing health checkup in China.
Detailed Description: Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors. To examine the diagnostic value of PG levels and Helicobacter pylori (Hp) status for GC and precancerous lesions screening in asymptomatic individuals undergoing health checkup in China. We operated a multicenter cross-sectional study of subjects who underwent health checkup at nine International Healthcare Centers in China. All participants underwent gastroscopy and pathological examination, serum PG, 13C-urea breath test, and/or Hp serological current infection marker rapid test, all on the same day. PG related parameters were analyzed in different Hp subgroups and regions.
Keywords
Eligibility
Minimum Age: 25 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Jilin City People's Hospital, Jilin, Jilin, China
Chinese PLA General Hospital, Beijing, , China
Sichuan Provincial People's Hospital, Chengdu, , China
The First Hospital affiliated to AMU (Southwest Hospital), Chongqing, , China
No. 924 Hospital of the People's Liberation Army of China, Guilin, , China
Jingzhou Hospital of Traditional Chinese Medicine, Jingzhou, , China
Kunshan Hospital of Traditional Chinese Medicine, Kunshan, , China
Shanghai Changhai Hospital, Shanghai, , China
Zhongshan Hospital affiliated to Xiamen University, Xiamen, , China
Contact Details
Name: Yi Zhao, Master
Affiliation: 2nd affiliated hospital of Zhejiang university, school of medicine
Role: PRINCIPAL_INVESTIGATOR
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