Spots Global Cancer Trial Database for Study of Weekly DCF to Treat Advanced Gastric Cancer
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Trial Identification
Brief Title: Study of Weekly DCF to Treat Advanced Gastric Cancer
Official Title: Phase II Study of Weekly Docetaxol Combined With Cisplatin and 5-Fu in Patients With Advanced Gastric Cancer
Study ID: NCT00568971
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to evaluate the efficacy of weekly docetaxol combined with cisplatin and 5-Fu in patients with AGC.
Detailed Description: Recently,in a multi-center, open-label randomized phase III study (V325), compared to the control arm of CF regimen, DCF showed higher efficacy in terms of response rate, time to progression and overall survival. But the regimen had increased grade 3-4 neutropenia (82% vs 57%) and febrile neutropenia infection (29% vs 12%). We began to study on weekly DCF in the patients with advanced gastric cancer to evaluate the efficacy no less than that of 3-week' regimen.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Fudan University Cancer Hospital, Shanghai, Shanghai, China
Contact Details
Name: Jin Li, PhD
Affiliation: Fudan University
Role: PRINCIPAL_INVESTIGATOR
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