Spots Global Cancer Trial Database for toxicity
Every month we try and update this database with for toxicity cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Induction Chemotherapy Followed by Chemoradiation With Cetuximab in Head and Neck Cancer | NCT00868491 | Head and Neck C... | docetaxel, cisp... radiotherapy cetuximab, cisp... | 18 Years - | Institute of Oncology Ljubljana | |
| Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment | NCT00839111 | Colorectal Neop... | sorafenib FOLFIRI | 18 Years - 75 Years | Fudan University | |
| Study of Apatinib as an Inhibitor of Tumor Angiogenesis | NCT00633490 | Tumor | apatinib | 18 Years - 70 Years | Fudan University | |
| A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) | NCT00960167 | Hepatocellular ... | 3DCRT or IMRT | 18 Years - 70 Years | National Taiwan University Hospital | |
| Treatment of Disseminated High Grade Lymphoma | NCT00536393 | Lymphoma | Doxorubicin Doxorubicin peg... | 60 Years - 75 Years | French Innovative Leukemia Organisation | |
| Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma | NCT03359018 | Progression-fre... Overall Surviva... Clinical Benefi... Toxicity | Apatinib SHR-1210 | 11 Years - | Peking University People's Hospital | |
| Study to Assess Various Sunitinib Schedules in Renal Cell Carcinoma | NCT02689167 | Kidney Neoplasm... Metastatic Rena... | Sunitinib | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| Apatinib for Inoperable Advanced Chondrosarcoma | NCT04260113 | Efficacy Toxicity, Drug | Apatinib Mesyla... | - | Peking University People's Hospital | |
| Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer | NCT02745639 | Rectal Neoplasm... | VMAT-SIB XELOX | 18 Years - | IRCCS Azienda Ospedaliero-Universitaria di Bologna | |
| Association of Dihydropyrimidine Dehydrogenase (DPYD) Variants With Toxicity Related to Capecitabine | NCT00478686 | Breast Cancer | Phlebotomy | - | M.D. Anderson Cancer Center | |
| Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer | NCT02484040 | Response to Tox... Toxicity Recurrence | Two-week course... Two-week course... | 20 Years - 80 Years | Seoul St. Mary's Hospital | |
| Weekly Versus Three-week Chemoradiation in Patients With Advanced Cervical Cancer | NCT01097252 | Cervical Cancer... | radiation weekly cisplati... tri-weekly cisp... | 30 Years - 75 Years | Korea Cancer Center Hospital | |
| ABlative Radiotherapy (for) Unfavorable Prostate Tumors | NCT04831983 | Prostate Cancer | 18 Years - 90 Years | University of Milano Bicocca | ||
| Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) | NCT01471444 | Disorder Relate... Leukemia Transplantation... | Fludarabine Clofarabine Busulfan Thymoglobulin Stem Cell Infus... Tacrolimus Methotrexate | 3 Years - 70 Years | M.D. Anderson Cancer Center | |
| Carbon Ion Radiotherapy for the Treatment of Localized Prostate Cancer | NCT02739659 | Prostate Carcin... | carbon-ion radi... | 20 Years - 85 Years | Shanghai Proton and Heavy Ion Center | |
| Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer | NCT03764553 | Esophageal Canc... | Liposomal Irino... Carboplatin Capecitabine Oxaliplatin 5-fluorouracil Leucovorin | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas | NCT01445535 | T-Cell Peripher... Gamma Delta Hep... Subcutaneous Pa... NK T-Cell Lymph... | Rituximab Etoposide Siplizumab Prednisone Vincristine Cyclophosphamid... Doxorubicin | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| Safety Study of the Chemotherapy Modulator PHY906 in Patients With Advanced Colorectal Cancer | NCT00036517 | Colorectal Neop... Diarrhea | PHY906 | 18 Years - 75 Years | PhytoCeutica | |
| DA-EDOCH14-R in Poor-prognosis Diffuse Large B-cell Lymphoma | NCT01066429 | Diffuse Large B... | Dexamethasone a... | 18 Years - 70 Years | Hospital Universitario Principe de Asturias | |
| Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously | NCT01543672 | Lung Cancer Metastatic Lung... | Stereotactic Bo... Stereotactic Bo... | 18 Years - | The Netherlands Cancer Institute | |
| Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies | NCT05743426 | Sarcoma Gastrointestina... | Survey Toxicity Assess... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| MILES-02: Study of Chemotherapy Treatment and Toxicity in Elderly Patients With Advanced Non Small Cell Lung Cancer | NCT00401492 | Non Small Cell ... | gemcitabine pro... cisplatin vinorelbine | 70 Years - | National Cancer Institute, Naples | |
| Pharmacogenomic and Pharmacokinetic Safety and Cost-saving Analysis in Patients Treated With Fluoropyrimidines | NCT00838370 | Neoplasms | Capecitabine, 5... | 18 Years - | The Netherlands Cancer Institute | |
| Testing a Spanish Version of a Patient Toxicity Questionnaire | NCT01517152 | Breast Cancer Colon Cancer Lung Cancer Lymphoma Myeloma | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| The Relationship Between Fat Free Mass and Toxicity of Cytostatics in Cancer Patients | NCT04528745 | Pancreas Cancer Colorectal Canc... | Bio Impedance S... | 18 Years - | University of Copenhagen | |
| Compare Lenalidomide and Subcutaneous Daratumumab vs Lenalidomide and Dexamethasone in Frail Subjects With Previously Untreated Multiple Myeloma Who Are Ineligible for High Dose Therapy | NCT03993912 | Multiple Myelom... | Daratumumab SC ... Lenalidomide PO... Dexamethasone P... | 65 Years - | University Hospital, Lille | |
| Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) | NCT01471444 | Disorder Relate... Leukemia Transplantation... | Fludarabine Clofarabine Busulfan Thymoglobulin Stem Cell Infus... Tacrolimus Methotrexate | 3 Years - 70 Years | M.D. Anderson Cancer Center | |
| Investigating Cardiovascular Adverse Events Related to Cancer Treatment | NCT03199300 | Toxicity Due to... Cardiovascular ... Cancer, Treatme... | Anthracyclines Trastuzumab Cisplatin Bleomycin | 18 Years - | University Medical Center Groningen | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC | NCT02734069 | Lung Cancer Sarcopenia Toxicity | Carboplatin | 18 Years - | Instituto Nacional de Cancerologia de Mexico | |
| Fludarabine Added to Induction Treatment in Untreated Multiple Myeloma Patients | NCT00382694 | Multiple Myelom... | Fludarabine | 18 Years - 64 Years | Nordic Myeloma Study Group | |
| HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer | NCT03424694 | Prostate Cancer | HDR brachythera... | 18 Years - 85 Years | CR-CSSS Champlain-Charles-Le Moyne | |
| Association of Dihydropyrimidine Dehydrogenase (DPYD) Variants With Toxicity Related to Capecitabine | NCT00478686 | Breast Cancer | Phlebotomy | - | M.D. Anderson Cancer Center | |
| Exclusive Intraoperative Radiation Therapy for Breast Cancer | NCT01276938 | Breast Neoplasm... Toxicity | 21 Gy radiation 18 Gy radiation | 45 Years - 85 Years | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | |
| Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy | NCT01829958 | Non Hodgkin Lym... Diffuse Large B... | rituximab prednisone Geriatric Asses... | 60 Years - | Memorial Sloan Kettering Cancer Center | |
| Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients | NCT01760356 | End Stage Liver... Rejection Infection Malignancy Toxicity Diabetes | 18 Years - 70 Years | UDA Centro Nacional Hepato-Bilio-Pancreático | ||
| CCRT for Esophageal Cancer. | NCT02607982 | Esophageal Canc... Concurrent Chem... Oxaliplatin Paclitaxel | Paclitaxel Oxaliplatin Radiotherapy | 18 Years - 80 Years | Hangzhou Cancer Hospital | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| Study of Apatinib as an Inhibitor of Tumor Angiogenesis | NCT00633490 | Tumor | apatinib | 18 Years - 70 Years | Fudan University | |
| Apatinib Versus Placebo as a Third Line Treatment in Patients With Advanced or Metastatic Gastric Cancer | NCT00970138 | Gastric Carcino... | apatinib tablet | 18 Years - 70 Years | Fudan University | |
| Adjuvant Radiotherapy in Breast With Intensity Modulated by Tomotherapy: | NCT02281149 | Breast Cancer | 18 Years - | Centre Oscar Lambret | ||
| Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC | NCT02734069 | Lung Cancer Sarcopenia Toxicity | Carboplatin | 18 Years - | Instituto Nacional de Cancerologia de Mexico | |
| Systemic Treatment Related Toxicity Identified With a Smartphone APPlication Measuring Step Count | NCT05927636 | Cancer Systemic Treatm... Physical Activi... Toxicity Due to... | 18 Years - | Radboud University Medical Center | ||
| Irinotecan and Anlotinib for Epithelioid Sarcoma | NCT05656222 | Objective Respo... Overall Surviva... | VIA combination... | 3 Years - | Peking University People's Hospital | |
| External Beam Radiotherapy for Muscle Invasive Bladder Cancer | NCT02748200 | Toxicity | external beam r... | 18 Years - 80 Years | University Hospital, Ghent | |
| Feasibility Study of the Xoft® Axxent® Electronic Brachytherapy System for the Treatment of Cervical Cancer | NCT01851772 | Cervical Cancer | Treatment with ... | - | Xoft, Inc. | |
| Volume De-escalation in Neoadjuvant Radiochemotherapy of Rectal Cancer | NCT03975452 | Toxicity | Reduced radiati... | 18 Years - | Campus Bio-Medico University | |
| Phase I and Pharmacokinetic Trial of Paclitaxel (Taxol) Given as a 3-Hour Infusion in Pediatric Patients With Refractory Malignancy | NCT00001387 | Neoplasms | paclitaxel | - | National Institutes of Health Clinical Center (CC) | |
| PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer | NCT03455608 | Dysphagia | RE-ACTIVE PRO-ACTIVE EAT PRO-ACTIVE EAT ... | 18 Years - | University Health Network, Toronto | |
| Treatment Selection According to Skin Reaction to Cetuximab | NCT01472653 | Head and Neck C... | cisplatin radiotherapy cetuximab | 18 Years - 70 Years | Institute of Oncology Ljubljana | |
| Prevention of Capecitabine Induced Hand and Foot Syndrome | NCT01291628 | Cancer | socks containin... | 18 Years - | Rabin Medical Center | |
| Delineation of Reducing Clinical Target Volume for Early-stage Nasopharyngeal Carcinoma Patients | NCT03839602 | Target Volume D... Early-stage Nas... Intensity Modul... | Reducing CTV | 18 Years - 70 Years | Sun Yat-sen University | |
| Irinotecan, Gemcitabine, Chemotherapy for Biliary Tract Cancer | NCT00832689 | Biliary Tract C... | Irinotecan and ... | 17 Years - 75 Years | Yonsei University | |
| Thymidylate Synthase Polymorphisms as a Predictor of Toxicity to Capecitabine Chemotherapy in Colon Cancer Treatment | NCT00126867 | Colon Cancer | 18 Years - | AHS Cancer Control Alberta | ||
| Efficacy of the Use of Bortezomib for the Treatment of Relapsed Leukemia or Positive MRD | NCT05137860 | Acute Lymphobla... Chemotherapeuti... Minimal Residua... | Bortezomib | 18 Years - 50 Years | Hospital General de Mexico | |
| InductionChemo-Radio-Antibody-Treatment | NCT01181401 | Squamous Cell C... Squamous Cell C... | TPF induction c... TPF experimenta... Standard Radioc... | 18 Years - | Charite University, Berlin, Germany | |
| A Scandinavian Sarcoma Group Protocol for Patients With High-risk Soft Tissue Sarcoma of the Extremities and Trunk Wall | NCT00790244 | Soft Tissue Sar... Non Metastatic ... | doxorubicin , i... doxorubicin, if... doxorubicin, if... doxorubicin, if... | 18 Years - 75 Years | Oslo University Hospital | |
| Nutritional Status and Pharmacological Treatment: Impact on the Toxicity and Quality of Life of Patients With Colorectal and Breast Cancer | NCT03759548 | Nutritional Sta... Colorectal Canc... Breast Cancer | Assessment of n... | 18 Years - | Federal University of Minas Gerais | |
| A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) | NCT00960167 | Hepatocellular ... | 3DCRT or IMRT | 18 Years - 70 Years | National Taiwan University Hospital | |
| Assessment of Cardiotoxicity After Chemotherapy for Breast Cancer by Cardio-vascular Magnetic Resonance (MR) | NCT00679874 | Breast Cancer | Cardio-vascular... | - | University of Calgary | |
| Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer | NCT02864849 | Rectal Cancer | Oxaliplatin Capecitabine Intensity modul... Total mesorecta... | 18 Years - 75 Years | Peking University Cancer Hospital & Institute | |
| Gemcitabine and Oxaliplatin (Gem-Ox) Plus Glivec in Gemcitabine-refractory Pancreatic Cancer | NCT01048320 | Advanced Pancre... | Gemcitabine Oxaliplatin Imatinib | 18 Years - | Royal Marsden NHS Foundation Trust | |
| Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma | NCT01005043 | Osteosarcoma | heavy ion radio... | 6 Years - | University Hospital Heidelberg | |
| HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer | NCT03424694 | Prostate Cancer | HDR brachythera... | 18 Years - 85 Years | CR-CSSS Champlain-Charles-Le Moyne | |
| Cross-linked Hyaluronan Gel Reduces Rectal Toxicity Due to Radiation Therapy for Prostate Cancer | NCT00882232 | Prostate Cancer | Cross-linked hy... | 18 Years - | Cancer Center of Irvine | |
| Assessing the Clinical Utility of Adding Pentoxifylline to Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients" | NCT06176339 | Breast Cancer F... | Pentoxifylline ... Placebo | 18 Years - 65 Years | Mansoura University | |
| Treatment Selection According to Skin Reaction to Cetuximab | NCT01472653 | Head and Neck C... | cisplatin radiotherapy cetuximab | 18 Years - 70 Years | Institute of Oncology Ljubljana | |
| Does Watercress Intake Have an Impact on Cancer Patients Outcomes: a Longitudinal Trial | NCT02468882 | Long-term Effec... | Watercress | 18 Years - 70 Years | University of Lisbon | |
| Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients | NCT05350722 | Breast Cancer | Single dose abl... | 50 Years - | Amsterdam UMC, location VUmc | |
| Dose Adaptation of Capecitabine Using Mobile Phone Toxicity Monitoring | NCT01053104 | Metastatic Colo... Metastatic Brea... | 18 Years - | University of Oxford | ||
| Nimotuzumab Combined With VMAT in Elderly Patients With Nasopharyngeal Carcinoma | NCT03915132 | Nasopharyngeal ... | Nimotuzumab VMAT | 70 Years - | ChineseAMS | |
| Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously | NCT01543672 | Lung Cancer Metastatic Lung... | Stereotactic Bo... Stereotactic Bo... | 18 Years - | The Netherlands Cancer Institute | |
| Exclusive Intraoperative Radiation Therapy for Breast Cancer | NCT01276938 | Breast Neoplasm... Toxicity | 21 Gy radiation 18 Gy radiation | 45 Years - 85 Years | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | |
| Navigation on Head and Neck Radiotherapy | NCT04857749 | Head and Neck C... | Standard care Navigation Nurs... | 18 Years - | Selcuk University | |
| Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors | NCT00679536 | Leukemia | Busulfan Fludarabine Thymoglobulin Total Body Irra... | - 21 Years | Ann & Robert H Lurie Children's Hospital of Chicago | |
| InductionChemo-Radio-Antibody-Treatment | NCT01181401 | Squamous Cell C... Squamous Cell C... | TPF induction c... TPF experimenta... Standard Radioc... | 18 Years - | Charite University, Berlin, Germany | |
| Bendamustine Plus Rituximab Versus Fludarabine Plus Rituximab | NCT01456351 | Non-Hodgkin's L... Mantle Cell Lym... | Bendamustine pl... Fludarabine 25 ... | 18 Years - | University of Giessen | |
| Surgical Staging in Cervical Cancer Prior to Chemoradiation | NCT01049100 | Cervical Cancer | lymphadenectomy Standard Stagin... | 18 Years - 70 Years | Charite University, Berlin, Germany | |
| A Phase I Study of SU101 in Pediatric Patients With Refractory Malignancy | NCT00001573 | Glioma Sarcoma | SU101 | - | National Institutes of Health Clinical Center (CC) |
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