Spots Global Cancer Trial Database for Proton Radiotherapy for Upper Gastrointestinal Malignancies
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Trial Identification
Brief Title: Proton Radiotherapy for Upper Gastrointestinal Malignancies
Official Title: A Feasibility and Registration Study of Proton Radiotherapy for Upper Gastrointestinal Malignancies
Study ID: NCT01449864
Conditions
Interventions
Study Description
Brief Summary: The primary objectives are to determine feasibility and the acute toxicity profile of proton therapy with concurrent continuous infusion 5-FU chemotherapy. Secondary objectives are to determine late toxicities and to generate preliminary data on clinical efficacy.
Detailed Description: This protocol invites patients with cancer of the upper digestive tract who will receive simultaneous proton radiation therapy and chemotherapy. The purpose of this study is to use a newer form of radiation therapy called proton radiation and to determine if its use is safe and effective in people with this type of cancer. Doctors will assess the safety of this method of treatment, record the side effects participants experience while receiving the standard dose of proton radiation.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Contact Details
Name: John Plastaras, MD, PhD
Affiliation: Abramson Cancer Center at Penn Medicine
Role: PRINCIPAL_INVESTIGATOR
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