Spots Global Cancer Trial Database for proton therapy

Every month we try and update this database with for proton therapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Mild Hypofractionation With Proton Therapy or Intensity Modulated Radiation Therapy (IMRT) for Intermediate-Risk Prostate Cancer	NCT01352429	Prostate Adenoc...	Proton Therapy IMRT	18 Years -	Abramson Cancer Center at Penn Medicine
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection	NCT02792582	Craniopharyngio...	Proton Therapy Surgery	- 21 Years	St. Jude Children's Research Hospital
Registry Study for Proton Therapy Clinical Outcomes and Long-Term Follow-up	NCT02070328	Cancer	Registry	-	Center for Biomedical Research, LLC
Registry for Analysis of Quality of Life, Normal Organ Toxicity and Survival of Pediatric Patients Treated With Proton Therapy	NCT02644993	Pediatric Cance...	Proton therapy	- 18 Years	Samsung Medical Center
Neurocognitive Function After Proton Therapy in Children and Adolescents	NCT04066465	Primary Brain T...		8 Years - 18 Years	Technische Universität Dresden
Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy	NCT05404308	Paramedical Con... Radiotherapy Proton Therapy Brain Tumor	Consultation wi... Consultation wi...	18 Years -	Centre Francois Baclesse
Ion Irradiation of Sacrococcygeal Chordoma	NCT01811394	Sacral Chordoma	protons carbon ions	18 Years - 80 Years	Heidelberg University
Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients.	NCT04367779	Brain Cancer Meningioma Sarcoma		-	Centre Leon Berard
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy	NCT05856773	Breast Cancer	Proton Therapy	19 Years -	Proton Collaborative Group
Early-Phase Safety of Proton Therapy Equipment	NCT02315989	Malignant Gliom... Hepatocellular ... Head and Neck M... Prostate Cancer	proton therapy	20 Years - 75 Years	Chang Gung Memorial Hospital
Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas	NCT00881595	Soft Tissue Sar...	Chemoradiothera... Proton therapy Proton Chemorad...	55 Years -	University of Florida
Varian ProBeam Proton Therapy System China Clinical Trial (Guangzhou)	NCT06338436	Tumor, Solid	Proton Radiatio...	18 Years - 80 Years	Varian, a Siemens Healthineers Company
Proton Radiation for Chordomas and Chondrosarcomas	NCT01449149	Chordomas Chondrosarcomas	Proton Therapy	18 Years -	Abramson Cancer Center at Penn Medicine
Pembrolizumab Plus Olaparib in LA-HNSCC	NCT05366166	Squamous Cell C...	Pembrolizumab Olaparib Cisplatin IMRT (intensity...	18 Years -	UNC Lineberger Comprehensive Cancer Center
Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer	NCT03186898	Unrectable or L...	Proton Therapy ... Photon Therapy ...	18 Years -	NRG Oncology
Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)	NCT04525989	Rectal Cancer	Radiation thera...	18 Years -	Karolinska University Hospital
Proton Therapy With Capecitabine for Rectal Cancer	NCT00503932	Rectal Cancer	Proton Therapy Capecitabine	18 Years -	M.D. Anderson Cancer Center
Proton Radiation Therapy Registry	NCT04376229	Cancer, Therapy...	Registry	18 Years - 100 Years	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pre-operative Hypofractionated Proton Therapy	NCT05917301	Soft Tissue Sar...	hypofractionati...	18 Years -	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)	NCT04525989	Rectal Cancer	Radiation thera...	18 Years -	Karolinska University Hospital
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas	NCT04832620	Bone Neoplasm o... Chordoma Chondrosarcoma Magnetic Resona... PET-CT Proton Therapy		50 Years -	Leiden University Medical Center
Early-Phase Safety of Proton Therapy Equipment	NCT02315989	Malignant Gliom... Hepatocellular ... Head and Neck M... Prostate Cancer	proton therapy	20 Years - 75 Years	Chang Gung Memorial Hospital
Changes in the MRI Signal in Patients With Benign Tumors of the Brain and Meninges Treated With Proton Therapy: Impact of TEL and the Biological Dose Received	NCT04584086	Benign Brain Tu... Proton Therapy	MRI 3 tesla	18 Years -	Centre Francois Baclesse
Varian ProBeam Proton Therapy System Clinical Trial (Shandong)	NCT06340815	Tumor, Solid	Radiation: Prot...	18 Years - 80 Years	Varian, a Siemens Healthineers Company
Impact of Continuous Positive Airway Pressure on Breathing Motion Amplitude	NCT02852473	Cancer	Continuous Posi...	18 Years -	Mayo Clinic
Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer	NCT04894643	Pancreatic Canc... Proton Therapy	Proton Ions Nab-PACLitaxel Gemcitabine Capecitabine Surgical resect...	18 Years -	EBG MedAustron GmbH
Study on the Safety and Effectiveness of Varian ProBeam Proton Therapy Equipment in the Treatment of Solid Tumors	NCT05914142	Solid Tumor Radiation Thera... Proton Therapy	Proton radiatio...	18 Years - 80 Years	Guangzhou Concord Cancer Center
Breast Cancer Lung Late Effects	NCT02725840	Radiation Injur... Breast Cancer	Proton beam rad... X-ray based rad... Computed Tomogr... Pulmonary Funct...	18 Years -	University of Florida
Study on the Safety and Effectiveness of Varian ProBeam Proton Therapy Equipment in the Treatment of Solid Tumors	NCT05914142	Solid Tumor Radiation Thera... Proton Therapy	Proton radiatio...	18 Years - 80 Years	Guangzhou Concord Cancer Center
Feasibility of High Dose PROton Therapy On Unresectable Primary Carcinoma Of Liver: Prospective Phase II Trial	NCT02632864	Liver Neoplasm Proton Therapy	Proton arm	20 Years -	Samsung Medical Center
Proton Beam Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis	NCT02571946	Liver Neoplasm Portal Vein Tum... Proton Therapy	Proton beam the...	20 Years -	Samsung Medical Center
Ion Irradiation of Sacrococcygeal Chordoma	NCT01811394	Sacral Chordoma	protons carbon ions	18 Years - 80 Years	Heidelberg University
Standard Follow-up Program (SFP) for Head and Neck Cancer Patients	NCT02435576	Head and Neck C...	Radiotherapy (p...	18 Years -	University Medical Center Groningen
APBI Proton Feasibility and Phase II Study	NCT01839838	Stage IA-IIA Br...	Proton Therapy	50 Years -	Abramson Cancer Center at Penn Medicine
Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients.	NCT04367779	Brain Cancer Meningioma Sarcoma		-	Centre Leon Berard
Proton Therapy in Reducing Toxicity in Anal Cancer	NCT03018418	Anus Neoplasms	Proton therapy Chemotherapy	18 Years -	University of Cincinnati
Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors	NCT05121545	Sarcoma Melanoma	Pro-GRID	18 Years -	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma	NCT02125786	Ependymoma	Irradiation Surgery ^1^8F-Fluorodeo... ^1^1C-methionin... Photon therapy Proton therapy	1 Year - 21 Years	St. Jude Children's Research Hospital
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors	NCT04908709	Malignant Brain...	Magnetic Resona... Proton Therapy	- 21 Years	Emory University
Virtual Reality for Children in Radiotherapy (REVER)	NCT04934293	Virtual Reality Proton Therapy Pediatric Cance...	Virtual reality	7 Years - 18 Years	Centre Antoine Lacassagne
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy	NCT04746729	Neoplasms	No intervention	- 22 Years	Institut National de la Santé Et de la Recherche Médicale, France
Proton Radiotherapy for Upper Gastrointestinal Malignancies	NCT01449864	Gastrointestina...	Proton therapy	18 Years -	Abramson Cancer Center at Penn Medicine
Protons vs. Photons for High-risk Prostate Cancer	NCT05350475	Prostate Cancer Radiotherapy Si...	Proton therapy Photon therapy	18 Years -	University of Aarhus
Prostate Cancer - Localized Adenocarcinoma Proton Therapy	NCT03285815	Prostate Adenoc...	Proton Therapy	-	National Cancer Center, Korea
APBI Proton Feasibility and Phase II Study	NCT01839838	Stage IA-IIA Br...	Proton Therapy	50 Years -	Abramson Cancer Center at Penn Medicine
Breast Cancer Lung Late Effects	NCT02725840	Radiation Injur... Breast Cancer	Proton beam rad... X-ray based rad... Computed Tomogr... Pulmonary Funct...	18 Years -	University of Florida
Registry for Analysis of Quality of Life, Normal Organ Toxicity and Survival of Pediatric Patients Treated With Proton Therapy	NCT02644993	Pediatric Cance...	Proton therapy	- 18 Years	Samsung Medical Center
Prostate Cancer Parameters for Patients Receiving Proton Treatment	NCT02110849	Prostate Cancer	Proton	18 Years -	Indiana University
Pre-operative Hypofractionated Proton Therapy	NCT05917301	Soft Tissue Sar...	hypofractionati...	18 Years -	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Evaluation of Proton Therapy in Pediatric Cancer Patients	NCT03223766	Tumor		-	St. Jude Children's Research Hospital
HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC	NCT05364411	Head and Neck S... Hypofractionati... Radiotherapy Proton Therapy Immune System S...	HYpofractionate... conventional fr...	18 Years -	Erasmus Medical Center
The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach	NCT04527900	Endometrial Can...	carboplatin and... pelvic IMPT (In...	18 Years -	University of Maryland, Baltimore
Varian ProBeam Proton Therapy System China Clinical Trial (Guangzhou)	NCT06338436	Tumor, Solid	Proton Radiatio...	18 Years - 80 Years	Varian, a Siemens Healthineers Company
Proton Radiation for Chordomas and Chondrosarcomas	NCT01449149	Chordomas Chondrosarcomas	Proton Therapy	18 Years -	Abramson Cancer Center at Penn Medicine
Short Term Outcomes After PRoton And photoN radiOtherapy for IDH Mutated Grade 2 and 3 Gliomas	NCT06180434	Glioma Radiotherapy; C...		18 Years -	Erasmus Medical Center
Adjuvant Proton Therapy or IMRT for the Treatment of Bladder Cancer	NCT01520038	Urothelial Carc...	Proton therapy IMRT	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Radiotherapy for Extremity Soft Tissue Sarcoma	NCT01561495	Soft Tissue Sar...	Proton Therapy	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Therapy to Reduce Acute Normal Tissue Toxicity in Locally Advanced Non-small-cell Lung Cancer	NCT02731001	Non-Small Cell ...	Proton therapy Photon therapy	18 Years - 70 Years	Technische Universität Dresden
Prostate Cancer Parameters for Patients Receiving Proton Treatment	NCT02110849	Prostate Cancer	Proton	18 Years -	Indiana University
Mild Hypofractionation With Proton Therapy or Intensity Modulated Radiation Therapy (IMRT) for Intermediate-Risk Prostate Cancer	NCT01352429	Prostate Adenoc...	Proton Therapy IMRT	18 Years -	Abramson Cancer Center at Penn Medicine
Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy	NCT05404308	Paramedical Con... Radiotherapy Proton Therapy Brain Tumor	Consultation wi... Consultation wi...	18 Years -	Centre Francois Baclesse
Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer	NCT04894643	Pancreatic Canc... Proton Therapy	Proton Ions Nab-PACLitaxel Gemcitabine Capecitabine Surgical resect...	18 Years -	EBG MedAustron GmbH
Prospective Registration Of Patient Data and Quality of Life in Eye Melanoma Patients	NCT05377957	Uveal Melanoma	Quality of life... Discrete choice... Shared decision... Impact of side-...	18 Years -	Leiden University Medical Center
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)	NCT04699773	Glioma Glioblastoma Brain Tumor	LITT Hypofractionate...	18 Years -	University of Maryland, Baltimore
Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy	NCT05404308	Paramedical Con... Radiotherapy Proton Therapy Brain Tumor	Consultation wi... Consultation wi...	18 Years -	Centre Francois Baclesse
Advanced Proton Therapy Approaches: a Multicenter High-quality Data Registry	NCT05860361	Cancer		18 Years -	European Institute of Oncology
Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma	NCT03267836	Meningioma Meningioma, Adu...	Avelumab Proton Therapy Surgery	18 Years -	Washington University School of Medicine
Proton Boost in Prostate Cancer	NCT03564275	Cancer of the P...	Proton Boost	18 Years -	University of Cincinnati
APBI Proton Feasibility and Phase II Study	NCT01839838	Stage IA-IIA Br...	Proton Therapy	50 Years -	Abramson Cancer Center at Penn Medicine
Advanced Proton Therapy Approaches: a Multicenter High-quality Data Registry	NCT05860361	Cancer		18 Years -	European Institute of Oncology
HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC	NCT05364411	Head and Neck S... Hypofractionati... Radiotherapy Proton Therapy Immune System S...	HYpofractionate... conventional fr...	18 Years -	Erasmus Medical Center
Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma	NCT03267836	Meningioma Meningioma, Adu...	Avelumab Proton Therapy Surgery	18 Years -	Washington University School of Medicine
Study of Hypofractionated Proton Radiation Therapy in Thoracic Malignancies	NCT01165658	Non-small Cell ... Small Cell Lung... Carcinoid Thymic Cancer Lung Cancer	Proton Therapy	18 Years -	M.D. Anderson Cancer Center
PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas	NCT05190172	Oligodendroglio... Oligodendroglio... Diffuse Astrocy...	Radiation thera...	18 Years - 65 Years	Oslo University Hospital
Proton Radiation Therapy Registry	NCT04376229	Cancer, Therapy...	Registry	18 Years - 100 Years	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy	NCT04746729	Neoplasms	No intervention	- 22 Years	Institut National de la Santé Et de la Recherche Médicale, France
Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial.	NCT01795300	Skull Base Meni...	Carbon Ion Radi... Proton Therapy Hypofractionate... Conventional Ph...	18 Years -	University Hospital Heidelberg
Adjuvant Proton Therapy or IMRT for the Treatment of Bladder Cancer	NCT01520038	Urothelial Carc...	Proton therapy IMRT	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Accelerated Partial Breast Irradiation	NCT03940248	Breast Cancer	Proton Accelera...	50 Years -	University of Cincinnati
Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas	NCT00881595	Soft Tissue Sar...	Chemoradiothera... Proton therapy Proton Chemorad...	55 Years -	University of Florida

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

Join others from around the world: