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Brief Title: A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma
Official Title: A Phase 1b, Open-label, Dose-Finding Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Subjects With Newly Diagnosed Glioblastoma
Study ID: NCT04324840
Brief Summary: The purpose of this study is to determine the safety and tolerability of CC-90010 when combined with standard of care treatment, temozolomide (TMZ) with or without radiotherapy (RT) in the newly diagnosed WHO Grade IV glioblastoma (ndGBM).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 800, New York, New York, United States
Local Institution - 503, Aalborg, , Denmark
Local Institution - 501, Copenhagen, , Denmark
Local Institution - 500, Odense, , Denmark
Local Institution - 201, Milano, , Italy
Local Institution - 202, Milan, , Italy
Local Institution - 204, Padova, , Italy
Local Institution - 200, Verona, , Italy
Local Institution - 408, Leiden, Zuid-Holland, Netherlands
Local Institution - 405, Amsterdam, , Netherlands
Local Institution - 400, Rotterdam, , Netherlands
Local Institution - 401, Utrecht, , Netherlands
Local Institution - 600, Oslo, , Norway
Local Institution - 311, A Coruna, , Spain
Local Institution - 306, Barcelona, , Spain
Local Institution - 302, Barcelona, , Spain
Local Institution - 303, Barcelona, , Spain
Local Institution - 307, Hospitalet de Llobregat, Barcelona, , Spain
Local Institution - 304, Madrid, , Spain
Local Institution - 301, Madrid, , Spain
Local Institution - 300, Madrid, , Spain
Local Institution - 310, Pamplona, , Spain
Local Institution - 309, Sevilla, , Spain
Local Institution - 305, Valencia, , Spain
Local Institution - 312, Vigo, , Spain
Local Institution - 702, Goteborg, , Sweden
Local Institution - 701, Lund, , Sweden
Local Institution - 700, Solna, , Sweden
Local Institution - 703, Uppsala, , Sweden
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR