Spots Global Cancer Trial Database for safety
Every month we try and update this database with for safety cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Safety Study of Two Oral Formulations of MGCD265 Administered in Healthy Subjects in the Fasting State | NCT01930006 | Advanced Malign... | MGCD265 | 18 Years - 55 Years | Mirati Therapeutics Inc. | |
| EUS-guided Ethanol-lipiodol Ablation of Pancreatic Neuroendocrine Tumor: a Prospective Study | NCT01902238 | Efficacy Safety Feasibility | EUS-guided etha... | 18 Years - | Asan Medical Center | |
| A Rollover Study to Provide Continued Treatment With GSK2118436 to Subjects With BRAF Mutation-Positive Tumors | NCT01231594 | Cancer | GSK2118436 GSK1120212 Other approved ... | 18 Years - | Novartis | |
| Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 5-6 | NCT06028672 | Gestational Tro... | Toripalimab Actinomycin-D | 18 Years - 60 Years | Peking Union Medical College Hospital | |
| Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix) Administered in Healthy Adolescents | NCT00534638 | Infections, Pap... | Cervarix Engerix-B | 12 Years - 15 Years | GlaxoSmithKline | |
| A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma | NCT04324840 | Glioblastoma | CC-90010 Temozolomide Radiotherapy | 18 Years - | Celgene | |
| Sequencing Of Endocrine Therapy In Post-Menopausal Women With Early Breast Cancer (FAST) | NCT01050634 | Post Menopausal... | Aromasin (exeme... | - | Pfizer | |
| Efficacy of Bortezomib (Velcade(R)) in Patients With Advanced Waldenström Macroglobulinemia | NCT00777738 | Waldenstrom Mac... | BORTEZOMIB | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Safety of the Use of Compressive Taping in Seroma | NCT03590704 | Seroma | Vitaltape® band... | - | Instituto Nacional de Cancer, Brazil | |
| Study Of AG-013736 (Axitinib) In Patients With Advanced Solid Tumors | NCT00447005 | Carcinoma | Axitinib (AG-01... | 20 Years - 75 Years | Pfizer | |
| Study to Assess Various Sunitinib Schedules in Renal Cell Carcinoma | NCT02689167 | Kidney Neoplasm... Metastatic Rena... | Sunitinib | 18 Years - | Centre Hospitalier Universitaire de Besancon | |
| Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis | NCT01865201 | Nasopharyngeal ... Brain Necrosis | Edaravone Common fundamen... | 18 Years - | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Feasibility and Safety of Physical Exercise in Men With Prostate Cancer | NCT04500080 | Prostate Cancer Androgen Depriv... Radiotherapy | PE Intervention | 18 Years - | Azienda Unità Sanitaria Locale Reggio Emilia | |
| Evaluation of Efficacy and Safety of FOLFIRI Association Treatment in Patients 70 Years of Age and Older With Gastric Cancer | NCT00210184 | Gastric Cancer | Irinotecan asso... | 70 Years - 100 Years | Institut Bergonié | |
| A Multi-Centre, Prospective, Non-Interventional Study to Intensively Monitor the Safety of Osimertinib in Clinical Practice Among Chinese NSCLC Patients | NCT03485326 | Non-small Cell ... | - | AstraZeneca | ||
| Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors | NCT05915481 | Advanced Solid ... Stereotactic Bo... Immune Checkpoi... Safety Efficacy | Cadonilimab Stereotactic bo... | 18 Years - 75 Years | Peking University Third Hospital | |
| Evaluation of Safety of a Vaccine Against Cervical Cancer in Healthy Korean Females | NCT01101542 | Infections, Pap... | Cervarix. Data collection | 10 Years - 25 Years | GlaxoSmithKline | |
| Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD) | NCT00862836 | Ovarian Cancer | Vandetanib | 18 Years - | Sanofi | |
| A Study Conducted in Subjects With Relapsed/Refractory Multiple Myeloma (MM); to Determine Dose of Afuresertib in Combination With Carfilzomib (Part 1) and to Investigate the Safety, Pharmacokinetic and Clinical Activity of the Combination Compared With Carfilzomib Alone (Part 2) | NCT02235740 | Cancer | Afuresertib Carfilzomib | 18 Years - | Novartis | |
| Pharmacokinetics Study of Nimotuzumab in Patients With Solid Tumors | NCT02395068 | Solid Tumors | Nimotuzumab irinotecan | 18 Years - 70 Years | Biotech Pharmaceutical Co., Ltd. | |
| A Phase 1/2, Open-label, Dose Finding Study to Evaluate CC-122 in Combination With Ibrutinib and Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | NCT02406742 | Leukemia, Lymph... | CC-122 Ibrutinib Obinutuzumab | 18 Years - 79 Years | Celgene | |
| IBD Cancer and Serious Infection in Europe | NCT02377258 | IBD | Non Interventio... | 18 Years - | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer | NCT02843581 | Metastatic Esop... | Cryosurgery NK immunotherap... | 30 Years - 70 Years | Fuda Cancer Hospital, Guangzhou | |
| Safety, Pharmacokinetics and Pharmacodynamics of Recombinant Chimeric Anti-CD20 Monoclonal Antibody in Patients With B-cell Non-Hodgkin's Lymphoma. | NCT02206308 | B-cell Non Hodg... | Chimeric anti-C... | 18 Years - 75 Years | Sinocelltech Ltd. | |
| Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma | NCT01466868 | Diffuse Large B... | MK2206 | 18 Years - 90 Years | Centre Leon Berard | |
| A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients. | NCT06298058 | Advanced Solid ... | SIBP-A13 formul... | 18 Years - 75 Years | Shanghai Institute Of Biological Products | |
| Effectiveness of Pharmacist Intervention on Capecitabine Relative Dose Intensity, Adherence, Knowledge & Safety Among Cancer Patients in Malaysia | NCT04175899 | Solid Tumor, Ad... | Pharmacist-led ... | 18 Years - | Ministry of Health, Malaysia | |
| A Phase Ⅰa Clinical Study Exploring Efficacy of SIBP-03 When Treating the Patients With Advanced Malignant Solid Tumors. | NCT05203601 | Tumor | SIBP-03 | 18 Years - 75 Years | Shanghai Institute Of Biological Products | |
| Safety and Efficacy of the Fully Humanized Anti - VEGF Monoclonal Antibody LYN00101 | NCT03644459 | Ovarian Cancer Cervical Cancer Colorectal Canc... Stomach Cancer | LYN00101 | 18 Years - 80 Years | Lynkcell Inc. | |
| Study of Oxaliplatin, Calcium Folinate, and 5-Fluorouracil as Neoadjuvant Chemotherapy for Resectable Advanced Gastric Cancer | NCT00591045 | Stomach Neoplas... Gastric Cancer | mFOLFOX | 30 Years - 70 Years | Peking University | |
| Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study) | NCT01997229 | Refractory Gene... | Eculizumab Placebo | 18 Years - | Alexion Pharmaceuticals, Inc. | |
| An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML) | NCT02775903 | Leukemia, Myelo... Myelodysplastic... | Azacitidine Durvalumab | 18 Years - | Celgene | |
| Effectivity and Safety of Irreversible Electroporation for Refractory Neoplasms in Liver and Pancreas | NCT02822066 | Refractory Neop... | Electroporation | 18 Years - 100 Years | First Affiliated Hospital of Zhejiang University | |
| A Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Combination With Bendamustine/Rituximab (BR) in Subjects With Relapsed or Refractory Non-Hodgkin's Lymphoma | NCT01594229 | Non-Hodgkin's L... | ABT-199 Rituximab Bendamustine | 18 Years - 99 Years | AbbVie | |
| Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis | NCT01865201 | Nasopharyngeal ... Brain Necrosis | Edaravone Common fundamen... | 18 Years - | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Capivasertib China PK Study | NCT04742036 | Advanced Solid ... | Capivasertib Paclitaxel | 18 Years - 130 Years | AstraZeneca | |
| Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors | NCT01031719 | H1N1 Influenza ... Invasive Solid ... | adjuvanted A(H1... non-adjuvanted ... non-adjuvanted ... | 2 Years - 70 Years | Chiltern Pesquisa Clinica Ltda | |
| A Study to Evaluate the Effect of Repeat Oral Dosing of GSK2118436 on Cardiac Repolarization in Subjects With V600 BRAF Mutation-Positive Tumors | NCT01738451 | Cancer | GSK2118436 75 m... Placebo | 18 Years - | GlaxoSmithKline | |
| Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma. | NCT04775173 | Kaposiform Hema... | Sirolimus | 1 Day - 14 Years | West China Hospital | |
| Hodgkin Lymphoma Treatment With Adcetris and Levact in the Old Patient | NCT02467946 | Clinical Effica... Safety | Adcetris-Levact | 60 Years - 80 Years | Centre Antoine Lacassagne | |
| Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation | NCT06243354 | Safety Tolerability Efficacy | Test product: H... | 18 Years - | Sichuan Huiyu Pharmaceutical Co., Ltd | |
| Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation | NCT02411019 | Cervical Intrae... | GX-188E | 19 Years - 50 Years | Genexine, Inc. | |
| TMS for the Treatment of Pancreatic Cancer Pain | NCT00324428 | Pain Visceral Pain Pancreatic Canc... | Transcranial Ma... | 18 Years - 65 Years | Beth Israel Deaconess Medical Center | |
| Capivasertib China PK Study | NCT04742036 | Advanced Solid ... | Capivasertib Paclitaxel | 18 Years - 130 Years | AstraZeneca | |
| The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists | NCT00224562 | Rheumatoid Arth... Crohn's Disease Ankylosing Spon... Psoriasis | TNF-alpha antag... | 0 Years - | Assistance Publique - Hôpitaux de Paris | |
| Safety, Tolerability and Immunogenic Response of CV-MG01 in Patients With Myasthenia Gravis | NCT02609022 | Myasthenia Grav... | CV-MG01 Placebo | 18 Years - 64 Years | CuraVac | |
| Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme | NCT00919737 | Malignant Gliom... | NPC-08 | 18 Years - 64 Years | Nobelpharma | |
| Irinotecan Hydrochloride Liposome Injection (LY01610) For Advanced Solid Tumors | NCT04088604 | Advanced Solid ... | LY01610 ( Irino... LY01610 ( Irino... Irinotecan Hydr... | 18 Years - 70 Years | Luye Pharma Group Ltd. | |
| Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma | NCT02342275 | Hemangioma | Propranolol Atenolol | - 24 Weeks | West China Hospital | |
| Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasias | NCT03959839 | Rectal Neoplasm... | ESD TAMIS TEO | 18 Years - | Puerta de Hierro University Hospital | |
| Kanglaite Injection Phase I Study | NCT00031031 | Solid Tumors Re... Neoplasms | Kanglaite Injec... | 18 Years - | KangLaiTe USA | |
| A Study of ASP2138 in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, Pancreatic Cancer | NCT05365581 | Gastric Adenoca... Gastroesophagea... Pancreatic Aden... | ASP2138 | 18 Years - | Astellas Pharma Inc | |
| Nalbuphine Versus Morphine for Perioperative Tumor Ablation | NCT05073744 | Nalbuphine Alle... Ablation Safety | Nalbuphine Morphine | 18 Years - 80 Years | Zhongda Hospital | |
| A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas | NCT03575351 | Lymphoma, Non-H... | Standard of Car... JCAR017 | 18 Years - 75 Years | Celgene | |
| Safety and Efficacy of Polyvinyl Alcohol Sodium Acrylate Embolization Microspheres for CRLM | NCT06021015 | Colorectal Canc... | Irinotecan and ... Irinotecan and ... | 18 Years - 80 Years | Zhongda Hospital | |
| Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study | NCT03629886 | Cervical Intrae... | HPV (Types 16, ... | 26 Years - | GlaxoSmithKline | |
| A Study to Determine Dose, Safety, Tolerability, Drug Levels, and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Participants With Multiple Myeloma | NCT02773030 | Multiple Myelom... | CC-220 Dexamethasone Daratumumab Bortezomib Carfilzomib | 18 Years - | Celgene | |
| Cetuximab With Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck in Chinese Subjects | NCT01012258 | Squamous Cell C... | Cetuximab + con... | 18 Years - | Merck KGaA, Darmstadt, Germany | |
| Efficacy and Safety of LY01005 in Patients With Breast Cancer Compared to ZOLADEX® | NCT05110170 | Breast Cancer | LY01005 ZOLADEX® 3.6 mg | 18 Years - 59 Years | Luye Pharma Group Ltd. | |
| Personalized DC Vaccine for Lung Cancer | NCT02956551 | Carcinoma, Non-... | DC vaccine | 18 Years - 90 Years | Sichuan University | |
| De-escalation Study for Stage IIa/IIb < 3 cm Seminoma | NCT05529251 | Seminoma Stage II | Radiotherapy bo... Carboplatin AUC... 3 cycles of EP | 18 Years - | Centre Leon Berard | |
| Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of AZD2014 | NCT01026402 | Advanced Solid ... | AZD2014 | 18 Years - 150 Years | AstraZeneca | |
| Maintenance Treatment With Capecitabine Metronomic Chemotherapy and Chinese Traditional Medicine in Metastatic Colorectal Cancer | NCT02575378 | Metastatic Colo... | Metronimic chem... Metronimic chem... | 18 Years - 75 Years | Ruijin Hospital | |
| The Safety and Tolerability of Secretrol in Patients With Barrett's Esophagus | NCT01905202 | Barrett's Esoph... | Secretrol | 18 Years - | Effexus Pharmaceutical | |
| Efficacy and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX® | NCT04563936 | Prostate Cancer | LY01005 3.6 mg ZOLADEX® 3.6 mg | 50 Years - | Luye Pharma Group Ltd. | |
| 64Cu-TLX592 Phase I Safety, PK, Biodistribution and Dosimetry Study (CUPID Study) | NCT04726033 | Metastatic Pros... | 64Cu-DOTA-TLX59... | - | Telix Pharmaceuticals (Innovations) Pty Limited | |
| Bintrafusp Alfa Program Rollover Study | NCT05061823 | Lung Cancer Cancer | Bintrafusp alfa | 18 Years - | EMD Serono | |
| An Open Study of ASP8273 in Patients With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations | NCT02192697 | Non-small Cell ... | ASP8273 | 20 Years - | Astellas Pharma Inc | |
| Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma | NCT00574288 | Multiple Myelom... | Part 1: Daratum... Part 2: Daratum... Methylprednisol... Dexamethasone | 18 Years - | Janssen Research & Development, LLC | |
| First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma | NCT04116658 | Glioblastoma, A... | Multiple dose o... | 18 Years - | Enterome | |
| Salpingectomy at Cesarean Delivery for Ovarian Cancer Reduction (SCORE) | NCT02374827 | Ovarian Cancer | Standard postpa... Complete Salpin... | 25 Years - | University of Alabama at Birmingham | |
| First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma | NCT04116658 | Glioblastoma, A... | Multiple dose o... | 18 Years - | Enterome | |
| Validation of an Adjusted Dosing Algorithm of Carboplatin | NCT02103244 | Cancer | Carboplatin | 18 Years - | Rijnstate Hospital | |
| Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics) | NCT02013297 | Brain Metastasi... Spinal Tumors Lung Tumors Ependymoma | SBRT treatment | 18 Months - 20 Years | Centre Leon Berard | |
| IFM2009-02-Pomalidomide and Dexamethasone Phase 2 Myeloma | NCT01053949 | Multiple Myelom... | Pomalidomide Pomalidomide | 19 Years - | University Hospital, Lille | |
| A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4 | NCT01409135 | Tumors Medical Oncolog... Neoplasms | AGS-22M6E ASG-22CE | 18 Years - | Astellas Pharma Inc | |
| Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies | NCT00013533 | Hodgkin Lymphom... Lymphocytic Leu... Mixed Cell Leuk... Myelodysplastic... Non Hodgkin's L... CML ALL AML Lymphoma | Stem cell trans... | 4 Years - 20 Years | National Institutes of Health Clinical Center (CC) | |
| Effect of Edaravone on Radiation-induced Temporal Lobe Necrosis | NCT01865201 | Nasopharyngeal ... Brain Necrosis | Edaravone Common fundamen... | 18 Years - | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Waterjet Versus Ultrasound Dissection During Hepatic Transection | NCT02041065 | Liver Tumour | Waterjet induce... CUSA induced di... | 18 Years - | Karolinska University Hospital | |
| An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404 | NCT01240642 | Metastatic Canc... Metastatic Canc... | ASA404 | 18 Years - | Novartis |
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