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Brief Title: Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma
Official Title: A Multi-center Phase II Study With Light Dose Escalation During Intraoperative Photodynamic Therapy of Glioblastoma
Study ID: NCT04391062
Brief Summary: The phase II study evaluate a light dose escalation in a classical intraoperative PDT regimen mediated by 5-ALA-PpIX, in glioblastoma patients with access to full surgical removal of the contrast enhancement. This treatment will be performed in addition to the current reference treatment of glioblastoma: maximum removal surgery followed by radiochemotherapy according to the Stupp protocol.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hôpital Erasme, Clinique Universitaire de Bruxelles, Brussels, , Belgium
Hopital Roger Salengro, CHU Lille, Lille, , France
Name: Nicolas Reyns, MD,PhD
Affiliation: University Hospital, Lille
Role: PRINCIPAL_INVESTIGATOR