Spots Global Cancer Trial Database for Venous Thromboembolism Prevention in Outpatients With Glioma
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Trial Identification
Brief Title: Venous Thromboembolism Prevention in Outpatients With Glioma
Official Title: Venous Thromboembolism Prevention in Outpatients With Glioma
Study ID: NCT05683808
Interventions
Study Description
Brief Summary: This is an open label study of apixaban for venous thromboembolism prevention in patients with newly diagnosed grade 4 glioma.
Detailed Description: Patients with primary brain tumors, including glioblastoma and astrocytoma, are at high risk of developing venous thromboemboli (VTE) as a comorbid condition. Prior studies have demonstrated safety and efficacy of primary pharmacological prevention of VTE using blood thinning medications, including apixaban. These studies have included a small cohort of patients with grade 4 glioma. The purpose of this study is to gather additional safety data regarding the use of apixaban for primary prevention of VTE in patients with newly diagnosed grade 4 glioma.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Contact Details
Name: Alissa A Thomas, MD
Affiliation: University of Vermont Medical Center
Role: PRINCIPAL_INVESTIGATOR
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