Spots Global Cancer Trial Database for astrocytoma
Every month we try and update this database with for astrocytoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA | NCT01269853 | Glioblastoma Mu... Anaplastic Astr... | Bevacizumab Bevacizumab | 18 Years - | Northwell Health | |
Implantable Microdevice In Primary Brain Tumors | NCT04135807 | Grade II Glioma Grade III Gliom... Grade IV Glioma Astrocytoma Oligodendroglio... Anaplastic Astr... Anaplastic Olig... Glioblastoma | Microdevice | 18 Years - | Dana-Farber Cancer Institute | |
XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | NCT00088166 | Brain Edema Brain Tumor | hCRF placebo hCRF | 18 Years - | Celtic Pharma Development Services | |
5-ALA in Recurrent Glioma | NCT02119338 | Glioma | 5-ala | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies | NCT05417594 | Advanced Solid ... | AZD9574 Temozolomide [11C]AZ1419 339... Datopotamab Der... Trastuzumab Der... | 18 Years - 130 Years | AstraZeneca | |
A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas | NCT00080054 | Glioma Glioblastoma Astrocytoma Oligodendroglio... Brain Neoplasm | Motexafin Gadol... | 18 Years - | Pharmacyclics LLC. | |
Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma | NCT06344130 | Astrocytoma Glioma Recurrent Gliob... | Radiation Thera... | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas | NCT00782626 | Glioma Low-grade Gliom... Astrocytoma | everolimus | 3 Years - 21 Years | Dana-Farber Cancer Institute | |
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB | NCT01125800 | Medulloblastoma Rhabdomyosarcom... Neuroblastoma Hepatoblastoma Glioma Astrocytoma | LDE225 | 12 Months - 18 Years | Novartis | |
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment | NCT05957679 | Spinal Cord Tum... | Magnetic Resona... Assessment and ... | 18 Years - 80 Years | Shengjing Hospital | |
Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma | NCT06108206 | Glioblastoma Anaplastic Astr... Astrocytoma Anaplastic Olig... | Adaptive Radiot... | 18 Years - | Columbia University | |
Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients | NCT00876499 | Brain Cancer | Questionnaire | 18 Years - | M.D. Anderson Cancer Center | |
Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) | NCT00335075 | Glioblastoma Astrocytoma | Temozolomide Semustine | 18 Years - | Merck Sharp & Dohme LLC | |
TVB- 2640 in Combination With Bevacizumab in Patients With First Relapse of High Grade Astrocytoma | NCT03032484 | Astrocytoma | Bevacizumab TVB-2640 | 18 Years - | The University of Texas Health Science Center at San Antonio | |
Safety Study of Afatinib for Brain Cancer | NCT02423525 | Brain Cancer | Afatinib | 18 Years - | Saint John's Cancer Institute | |
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors | NCT02684058 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon... | Dabrafenib trametinib Carboplatin Vincristine | 12 Months - 17 Years | Novartis | |
Natural History of Patients With Brain and Spinal Cord Tumors | NCT00009035 | Astrocytoma Oligodendroglio... Glioblastoma Glioma Anaplastic Glio... | 1 Year - 100 Years | National Institutes of Health Clinical Center (CC) | ||
Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
Correlation Between Psychological Stress and Progression of Diffuse Astrocytoma Towards Secondary Glioma | NCT05532969 | Astrocytoma | stressors | 18 Years - 75 Years | Henan Provincial People's Hospital | |
Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) | NCT00335075 | Glioblastoma Astrocytoma | Temozolomide Semustine | 18 Years - | Merck Sharp & Dohme LLC | |
Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors | NCT03220646 | Brain Tumor | abemaciclib abemaciclib | 18 Years - | Memorial Sloan Kettering Cancer Center | |
A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma | NCT03150862 | Brain and Centr... | Pamiparib TMZ Radiation | 18 Years - | BeiGene | |
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma | NCT02010606 | Glioblastoma Glioblastoma Mu... Glioma Astrocytoma Brain Tumor | Dendritic cell ... Dendritic cell ... | 18 Years - | Cedars-Sinai Medical Center | |
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S | NCT04430842 | Astrocytoma Brain Cancer Brain Metastase... Bladder Cancer Breast Cancer Cervical Cancer Cholangiocarcin... Colorectal Canc... Esophagus Cance... Gastric Cancer Head and Neck C... Kidney Cancer Liver Cancer Lung Cancer Melanoma Ovarian Cancer Pancreatic Canc... Pleural Mesothe... Prostate Cancer Sarcoma Tongue Cancer Thymic Carcinom... Urinary Tract C... | QBS10072S | 18 Years - | Quadriga Biosciences, Inc. | |
Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma | NCT03072134 | Glioma Anaplastic Astr... Anaplastic Olig... Anaplastic Olig... Glioblastoma Mu... Astrocytoma, Gr... Astrocytoma, Gr... Brain Cancer | Neural stem cel... | 18 Years - | Northwestern University | |
Natural History of and Specimen Banking for People With Tumors of the Central Nervous System | NCT02851706 | Brain Cancer Brain Tumor Spine Cancer Spine Tumor Neoplasm | No Treatment | 18 Years - | National Institutes of Health Clinical Center (CC) | |
SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745) | NCT00783393 | Astrocytoma | Temozolomide | 18 Years - | Merck Sharp & Dohme LLC | |
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors | NCT00994071 | Medulloblastoma Pontine Glioma Ependymoma Astrocytoma PNET | Temozolomide ABT-888 | - 21 Years | National Institutes of Health Clinical Center (CC) | |
Pediatric Long-Term Follow-up and Rollover Study | NCT03975829 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos... | dabrafenib trametinib | 1 Year - | Novartis | |
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma | NCT02010606 | Glioblastoma Glioblastoma Mu... Glioma Astrocytoma Brain Tumor | Dendritic cell ... Dendritic cell ... | 18 Years - | Cedars-Sinai Medical Center | |
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas | NCT03956706 | Glioblastoma Astrocytoma, Gr... Astrocytoma, Gr... Malignant Gliom... | Stereotactic Ra... | 18 Years - | Northwell Health | |
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment | NCT05957679 | Spinal Cord Tum... | Magnetic Resona... Assessment and ... | 18 Years - 80 Years | Shengjing Hospital | |
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma | NCT01290692 | Grade IV Glioma Grade IV Astroc... Glioblastoma Mu... | TVI-Brain-1 | 18 Years - | TVAX Biomedical | |
Genetic Analysis of Brain Tumors | NCT00031538 | Glioma Glioblastoma Mu... Anaplastic Astr... Oligodendroglio... Astrocytoma | 1 Year - 99 Years | National Institutes of Health Clinical Center (CC) | ||
Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants | NCT03649464 | Glioblastoma Astrocytoma Oligodendroglio... | OKN-007 | 18 Years - | Oblato, Inc. | |
Pediatric Long-Term Follow-up and Rollover Study | NCT03975829 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos... | dabrafenib trametinib | 1 Year - | Novartis | |
Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma | NCT05561374 | High-grade Glio... Oligodendroglio... Astrocytoma Glioblastoma Mu... | Low-dose OKN-00... Low-dose OKN-00... Mid-dose OKN-00... High-dose OKN-0... | 18 Years - | Oblato, Inc. | |
Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma | NCT05236036 | Astrocytoma Glioblastoma Glioblastoma, I... MGMT-Unmethylat... Recurrent Gliob... | Mycophenolate M... Quality-of-Life... Radiation Thera... Temozolomide | 18 Years - | Northwestern University | |
Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062) | NCT00705198 | Glioma Astrocytoma | Temozolomide (f... Temozolomide (f... Radiotherapy (f... | - | Merck Sharp & Dohme LLC | |
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients | NCT01579253 | Glioblastoma Nervous System ... Central Nervous... Astrocytoma Glioma Neoplasms, Neur... Neuroectodermal... Neoplasms by Hi... Neoplasms, Nerv... | 18 Years - 75 Years | Ludwig-Maximilians - University of Munich | ||
Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning | NCT05624736 | Astrocytoma Glioblastoma Mu... Oligodendroglio... | multi-parametri... Pathology exami... | 18 Years - 90 Years | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | |
Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma | NCT01649830 | Astrocytoma Oligodendroglio... Oligodendroastr... | Radiotherapy Temozolomide | 18 Years - 60 Years | Sun Yat-sen University | |
A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy | NCT03149003 | Glioblastoma | DSP-7888 Dosing... Bevacizumab | 18 Years - | Sumitomo Pharma America, Inc. | |
Dexanabinol in Patients With Brain Cancer | NCT01654497 | Brain Cancer | Dexanabinol | 18 Years - | University of California, San Diego | |
Vorasidenib Expanded Access Program | NCT05592743 | Glioma Recurrence Disease Attribu... Pathologic Proc... Neoplasms, Neur... Neuroectodermal... Neoplasms, Germ... Neoplasms by Hi... Neoplasms Neoplasms, Glan... Neoplasms, Nerv... | Vorasidenib | 12 Years - | Servier | |
Safety Study of Afatinib for Brain Cancer | NCT02423525 | Brain Cancer | Afatinib | 18 Years - | Saint John's Cancer Institute | |
Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants | NCT03649464 | Glioblastoma Astrocytoma Oligodendroglio... | OKN-007 | 18 Years - | Oblato, Inc. | |
Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma | NCT05341947 | Recurrent Gliob... | Activated T cel... | 18 Years - | Cedars-Sinai Medical Center | |
Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma | NCT01089244 | Astrocytoma Oligoastrocytom... Oligodendroglio... | 18 Years - | Ludwig-Maximilians - University of Munich | ||
(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas | NCT01281982 | Low Grade Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Oligoastrocytom... | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors | NCT02372409 | Glioma Pilocytic Astro... Anaplastic Astr... Glioblastoma Mixed Oligoastr... Mixed Glioma Oligodendroglio... Optic Glioma Astrocytoma | MRI-guided lase... Doxorubicin Etoposide Dynamic contras... Dynamic suscept... | 3 Years - 21 Years | Washington University School of Medicine | |
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors | NCT02684058 | Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon... | Dabrafenib trametinib Carboplatin Vincristine | 12 Months - 17 Years | Novartis | |
A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma | NCT00683761 | Malignant Gliom... Glioblastoma Mu... GBM Astrocytoma Oligodendroglio... | 131I-TM601 | 18 Years - | TransMolecular | |
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma | NCT02709226 | Astrocytoma, Gr... Giant Cell Glio... Glioblastoma Mu... Gliosarcoma | Radiation | 18 Years - | National Institutes of Health Clinical Center (CC) | |
Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas | NCT01502605 | Astrocytoma Glioma | 5-Aminolevulini... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
Investigational Imaging Technique During Brain Surgery | NCT05513859 | Astrocytoma Glioblastoma Oligodendroglio... | Craniotomy Quantitative Ob... | 18 Years - | Emory University | |
Investigational Imaging Technique During Brain Surgery | NCT05513859 | Astrocytoma Glioblastoma Oligodendroglio... | Craniotomy Quantitative Ob... | 18 Years - | Emory University | |
A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas | NCT02209428 | Astrocytoma Oligodendroglio... Oligoastrocytom... | Temozolomide | 18 Years - 40 Years | Huashan Hospital | |
Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) | NCT00723827 | Glioblastoma Glioma Astrocytoma | Temozolomide Radiotherapy | - | Merck Sharp & Dohme LLC | |
Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP) | NCT00624728 | High-grade Glio... Astrocytoma Glioblastoma | 18F Fluorothymi... | 18 Years - | University Hospital, Bordeaux | |
SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745) | NCT00783393 | Astrocytoma | Temozolomide | 18 Years - | Merck Sharp & Dohme LLC | |
Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive Enhancing IDH-1 Mutant Glioma | NCT05484622 | Astrocytoma | Vorasidenib Pembrolizumab | 18 Years - | Servier | |
5-ALA in Recurrent Glioma | NCT02119338 | Glioma | 5-ala | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas | NCT03956706 | Glioblastoma Astrocytoma, Gr... Astrocytoma, Gr... Malignant Gliom... | Stereotactic Ra... | 18 Years - | Northwell Health | |
The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) | NCT00392171 | Glioma Astrocytoma Oligodendroglio... Glioblastoma | Temozolomide | 19 Years - 70 Years | Merck Sharp & Dohme LLC | |
CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma | NCT04047303 | Astrocytoma Glioblastoma | CC-90010 | 18 Years - | Celgene | |
FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma | NCT01089244 | Astrocytoma Oligoastrocytom... Oligodendroglio... | 18 Years - | Ludwig-Maximilians - University of Munich | ||
A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations | NCT02381886 | Advanced Malign... | IDH305 | 18 Years - | Novartis | |
A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes | NCT01251913 | Ependymomas Gliomas PNET Pineal Tumors PCNSL (Primary ... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma | NCT01044966 | Glioblastoma Mu... Glioma Astrocytoma Brain Tumor | ITV DepoCyt + T... | 18 Years - 85 Years | Medical University of South Carolina | |
A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes | NCT01251913 | Ependymomas Gliomas PNET Pineal Tumors PCNSL (Primary ... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain | NCT01403311 | Glioma | 5-Aminolevuline... | 18 Years - | Legacy Health System | |
A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma | NCT00389090 | Glioma Astrocytoma Oligodendroglio... Oligoastrocytom... | Temozolomide an... | 18 Years - | Keryx / AOI Pharmaceuticals, Inc. | |
Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive Enhancing IDH-1 Mutant Glioma | NCT05484622 | Astrocytoma | Vorasidenib Pembrolizumab | 18 Years - | Servier | |
Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology | NCT04648462 | Astrocytoma Ependymoma Ganglioglioma Oligodendroglio... Optic Nerve Gli... Meningioma Nerve Sheath Ne... Adenoma Craniopharyngio... Hemangiopericyt... Germinoma Neurilemmoma | ProTRAIT | 18 Years - | Maastricht Radiation Oncology | |
Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas | NCT06241391 | Glioma Astrocytoma Anaplastic Astr... Oligodendroglio... Glioblastoma Mu... | PSMA PET-CT | 18 Years - | All India Institute of Medical Sciences, Bhubaneswar | |
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors | NCT01351519 | Malignant Gliom... Glioma Glioblastoma Glioblastoma Mu... Astrocytoma | Aminolevulinic ... | 18 Years - | MultiCare Health System Research Institute | |
Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
Antineoplaston Therapy in Treating Children With Brain Tumors | NCT00003458 | Childhood Brain... | Antineoplaston ... | 6 Months - 18 Years | Burzynski Research Institute |