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Brief Title: Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas
Official Title: Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas
Study ID: NCT04617002
Brief Summary: This is an intermediate-size expanded access protocol to provide ONC201 (dordaviprone) to patients with H3 K27M-mutant and/or midline gliomas who cannot access ONC201 (dordaviprone) through clinical trials.
Detailed Description:
Minimum Age: 0 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
BMDACC at Banner University Medical Center Phoenix, Phoenix, Arizona, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
Children's Hospital of Orange County, Orange, California, United States
Rady Children's Hospital, San Diego, California, United States
Providence Saint John's Health Center, Santa Monica, California, United States
Children's Hospital of Colorado, Aurora, Colorado, United States
Children's National Medical Center, Washington, District of Columbia, United States
Miami Cancer Institute, Miami, Florida, United States
University Cancer & Blood Center, Athens, Georgia, United States
Kapi'olani Medical Center for Women and Children, Honolulu, Hawaii, United States
Lurie Children's Hospital, Chicago, Illinois, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
University of Michigan, Ann Arbor, Michigan, United States
University of Minnesota, Minneapolis, Minnesota, United States
Washington University in St. Louis, Saint Louis, Missouri, United States
University of Nebraska Medical Center - Adults Only, Omaha, Nebraska, United States
Overlook Medical Center/ Atlantic Health System, Summit, New Jersey, United States
Albany Medical Center, Albany, New York, United States
New York University Langone - Active, Enrolling, New York, New York, United States
University of Rochester, Rochester, New York, United States
Providence Neurological Specialties Clinic, Portland, Oregon, United States
University of Texas Southwestern, Dallas, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
Huntsman Cancer Institute, Salt Lake City, Utah, United States
Children's Hospital of The King's Daughters, Norfolk, Virginia, United States