Spots Global Cancer Trial Database for glioma
Every month we try and update this database with for glioma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Safety and Efficacy of IDH1R132H-DC Vaccine in Gliomas | NCT02771301 | Glioma | dendritic cells | 18 Years - 70 Years | Hebei Yanda Hospital | |
| Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program | NCT01772771 | Glioma Hematopoietic a... Malignant Solid... Melanoma Sarcoma | Biospecimen Col... Genetic Testing Medical Chart R... | - | M.D. Anderson Cancer Center | |
| A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | NCT01188096 | Brain Tumors | Poly ICLC | - 21 Years | Wake Forest University Health Sciences | |
| Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors | NCT01661400 | Glioma Neuroectodermal... Wilms Tumor Rhabdomyosarcom... Sarcoma, Ewing Osteosarcoma Retinoblastoma | Metronomic Cycl... Thalidomide | 6 Months - 21 Years | Washington University School of Medicine | |
| Multimodal Imaging of Hypoxia in Gliomas | NCT03716986 | Glioma | MRI Oxygen Satu... | 18 Years - | University Hospital, Caen | |
| Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide | NCT00250211 | Glioblastoma Glioma | Functional MRI ... | 18 Years - 65 Years | AHS Cancer Control Alberta | |
| An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma | NCT00880061 | Brain Neoplasm Glioma | IL13-PE38QQR | - 17 Years | National Institutes of Health Clinical Center (CC) | |
| Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | NCT05634707 | Primary Brain T... Brain Tumor, Re... | Fluoxetine Temozolomide | 24 Years - | Duke University | |
| The circTeloDIAG: Liquid Biopsy for Glioma Tumor | NCT04931732 | Glioma | ctDNA analysis | 18 Years - 90 Years | Hospices Civils de Lyon | |
| BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma | NCT00727506 | Glioma | BIBW 2992 TMZ BIBW 2992 plus ... | 18 Years - | Boehringer Ingelheim | |
| Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors | NCT05383872 | Glioblastoma Glioma Liquid Biopsy | Focused Ultraso... | 18 Years - 80 Years | InSightec | |
| Phase II Trial of Peginterferon Alpha-2b and Thalidomide in Adults With Recurrent Gliomas | NCT00047879 | Glioma | PEG-interferon ... Thalidomide | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion | NCT05990244 | Glioma | Magnetic Resona... Assessment and ... | 18 Years - 80 Years | Shengjing Hospital | |
| A Microdose Evaluation Study of ABY-029 in Recurrent Glioma | NCT02901925 | Glioma | ABY-029 | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM) | NCT00290771 | Recurrent Gliob... | Imatinib tablet... Hydroxyurea cap... | 18 Years - | Novartis | |
| Long Term Follow up of Patients Under 5 Years of Age With High Grade Glioma Diagnosed in France Between 1990 and 2015 | NCT03690570 | Glioma | 1 Day - 5 Years | University Hospital, Strasbourg, France | ||
| Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | NCT02833701 | Glioblastoma Glioma | Ascorbic Acid Bevacizumab Laboratory Biom... Quality-of-Life... | 19 Years - | University of Nebraska | |
| The Study of Microglia/Macrophages Involved Dynamic Evolution of Glioma Microenvironment and the Function and Visualization of Targeted Molecules of Glioma | NCT04781764 | Glioma | surgery | 18 Years - 80 Years | Huashan Hospital | |
| Non Invasive IDentification of Gliomas With IDH1 Mutation | NCT01703962 | Non Invasive Di... | 18 Years - 65 Years | Institut National de la Santé Et de la Recherche Médicale, France | ||
| 18F-Fluciclovine PET-MRI in High-grade Glioma | NCT05553041 | Glioma High Grade Glio... Glioma, Maligna... Glioma Intracra... Diffuse Glioma | 18F-Fluciclovin... | 1 Year - 21 Years | Children's Hospital of Philadelphia | |
| 5-ALA in Recurrent Glioma | NCT02119338 | Glioma | 5-ala | 18 Years - | St. Joseph's Hospital and Medical Center, Phoenix | |
| Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies | NCT03638206 | B-cell Acute Ly... Lymphoma Myeloid Leukemi... Multiple Myelom... Hepatoma Gastric Cancer Pancreatic Canc... Mesothelioma Colorectal Canc... Esophagus Cance... Lung Cancer Glioma Melanoma Synovial Sarcom... Ovarian Cancer Renal Carcinoma | CAR-T cell immu... | 4 Years - 70 Years | Shenzhen BinDeBio Ltd. | |
| Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG | NCT05555550 | Glioma Low-grade Gliom... Low Grade Gliom... Glioma, Maligna... Glioma Intracra... | 18F-Fluciclovin... | 1 Year - 21 Years | Children's Hospital of Philadelphia | |
| [11C]Acetate PET in Patients With Glioma | NCT02986815 | Glioma | [11C]Acetate Br... | 18 Years - | University of Texas Southwestern Medical Center | |
| Study of a c-Met Inhibitor PLB1001 in Patients With PTPRZ1-MET Fusion Gene Positive Recurrent High-grade Gliomas | NCT02978261 | Glioma | PLB1001 | 18 Years - | Beijing Pearl Biotechnology Limited Liability Company | |
| Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies | NCT05417594 | Advanced Solid ... | AZD9574 Temozolomide [11C]AZ1419 339... Datopotamab Der... Trastuzumab Der... | 18 Years - 130 Years | AstraZeneca | |
| Integrated Discovery of New Immuno-Molecular Actionable Biomarkers for Tumors With Immune-suppressed Environment | NCT03706625 | Non Hodgkin Lym... Non Small Cell ... Glioma | 18 Years - | Assistance Publique - Hôpitaux de Paris | ||
| Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma | NCT00761280 | Anaplastic Astr... Glioblastoma | trabedersen temozolomide Drug delivery s... Placement of Dr... carmustine lomustine | 18 Years - 70 Years | Isarna Therapeutics GmbH | |
| Radiogenomic and Prognosis Analysis in Glioma | NCT04122521 | Glioma | MRI | 18 Years - | Asan Medical Center | |
| Repurposed Drugs in Research for Cancer Clinical Trials- Pitavastatin | NCT05977738 | Glioblastoma Mu... Recurrent Gliob... | Pitavastatin ca... | 18 Years - | Erasmus Medical Center | |
| Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging | NCT01699269 | High Grade Brai... | peritumoral gli... | 18 Years - 85 Years | University Hospital, Clermont-Ferrand | |
| Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1) | NCT00797940 | Glioblastoma Mu... | IL-4PE | 18 Years - | Protox Inc. | |
| A Dose-Escalation Study in Participants With Recurrent Malignant Glioma | NCT01682187 | Glioma | LY2157299 Lomustine | 18 Years - | Eli Lilly and Company | |
| ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma | NCT03322813 | Glioma | ExAblate 4000 -... | 21 Years - 85 Years | InSightec | |
| Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma | NCT01898273 | Glioblastoma | I-124-CLR1404 | 18 Years - | Cellectar Biosciences, Inc. | |
| Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma | NCT04543201 | Glioma | Early START vis... | 18 Years - | University of Rochester | |
| A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas | NCT00080054 | Glioma Glioblastoma Astrocytoma Oligodendroglio... Brain Neoplasm | Motexafin Gadol... | 18 Years - | Pharmacyclics LLC. | |
| Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma | NCT01105702 | Brain Cancer | Temozolomide Bevacizumab Lithium Carbona... Radiation | 18 Years - | NYU Langone Health | |
| CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR | NCT02331693 | Advanced Glioma | anti-EGFR CAR T | 18 Years - 70 Years | RenJi Hospital | |
| Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation | NCT02073994 | Cholangiocarcin... Chondrosarcoma Glioma Other Advanced ... | AG-120 | 18 Years - | Servier | |
| Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM | NCT00597493 | Recurrent Gliob... | Sorafenib and T... | 18 Years - | Duke University | |
| ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | NCT01473485 | Glioma Metastatic Brai... | ExAblate Transc... | 18 Years - 75 Years | InSightec | |
| Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma | NCT00979173 | Glioma | AC480 | 18 Years - | Duke University | |
| Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma | NCT06344130 | Astrocytoma Glioma Recurrent Gliob... | Radiation Thera... | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma | NCT03058198 | Glioma | 89Zr-ABT806 PET | 18 Years - | Huashan Hospital | |
| Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors | NCT04541225 | Glioma Glioma, Maligna... Glioma, Mixed Glial Cell Tumo... Breast Cancer Breast Carcinom... Cancer of Breas... Cancer of the B... Breast Tumor Malignant Tumor... Advanced Breast... Advanced Breast... Metastatic Brea... Metastatic Brea... Prostate Cancer Prostatic Cance... Cancer of Prost... Cancer of the P... Prostate Neopla... Castrate Resist... Castration-resi... Castration Resi... Glioblastoma Recurrent Gliob... | NUV-422 | 18 Years - | Nuvation Bio Inc. | |
| Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma | NCT05045027 | Glioma Malignant Gliom... Recurrent Gliom... Recurrent Malig... | Biospecimen Col... Diagnostic Imag... Magnetic Resona... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas | NCT00782626 | Glioma Low-grade Gliom... Astrocytoma | everolimus | 3 Years - 21 Years | Dana-Farber Cancer Institute | |
| Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption | NCT03551249 | Glioma Glioblastoma | Focused ultraso... | 18 Years - 80 Years | InSightec | |
| Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma | NCT02046187 | Glioblastoma (G... | Ketogenic Diet Radiation thera... Temozolomide | 18 Years - 80 Years | St. Joseph's Hospital and Medical Center, Phoenix | |
| A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB | NCT01125800 | Medulloblastoma Rhabdomyosarcom... Neuroblastoma Hepatoblastoma Glioma Astrocytoma | LDE225 | 12 Months - 18 Years | Novartis | |
| MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment | NCT05957679 | Spinal Cord Tum... | Magnetic Resona... Assessment and ... | 18 Years - 80 Years | Shengjing Hospital | |
| Feasibility of Individualized Therapy for Recurrent Glioblastoma | NCT03681028 | Recurrent Gliob... | Individualized ... | 18 Years - | University of California, San Francisco | |
| Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery | NCT01798771 | Primary Maligna... Glioma Glioblastoma Metastasis | Interventional ... Control arm | 18 Years - | Johann Wolfgang Goethe University Hospital | |
| Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor | NCT01171469 | Brain Tumor Glioblastoma Medulloblastoma Ependymoma Anaplastic Astr... | Dendritic Cells Imiquimod | - | Masonic Cancer Center, University of Minnesota | |
| Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade | NCT03493932 | Glioblastoma | Nivolumab BMS-986016 | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently | NCT03496181 | Glioma Glioma of Brain Glioma of Spina... | Multilingual Ap... Language paradi... Language paradi... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors | NCT00977327 | Glioma | Intraoperative ... Intraoperative ... | 18 Years - | Tel-Aviv Sourasky Medical Center | |
| Biomarker-based Algorithm for Diagnosis of Glioma | NCT04194593 | Glioma | PCR (Polymerase... | 18 Years - | Hospices Civils de Lyon | |
| The Etiology and Progression of Brain Tumors | NCT01811524 | Brain Tumor Glioma Meningioma | 1 Month - 85 Years | Tampere University Hospital | ||
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases | NCT04752267 | Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon... | Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi... | 18 Years - | University of Southern California | |
| Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma | NCT01778088 | Glioma | I-131-CLR1404 I... | 18 Years - | Cellectar Biosciences, Inc. | |
| Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas | NCT00031083 | Glioblastoma Mu... Anaplastic Astr... Oligoastrocytom... Gliosarcoma | Interferon-beta | 18 Years - | Biogen | |
| Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors | NCT00870129 | Brain Cancer Glioma | MRI and advance... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Gene Expression, Immunological Status and Metabolome in Glioma Patients | NCT01525459 | Glioma | Glioma resectio... Blood sampling | 20 Years - 80 Years | National Institute of Biology, Slovenia | |
| An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors | NCT04539574 | Central Nervous... Glioma Metastatic Mali... Metastatic Mali... | 7 Tesla Magneti... Questionnaire A... | 18 Years - | M.D. Anderson Cancer Center | |
| Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme. | NCT02433392 | Glioma | CM-BC2 | 18 Years - | Boston Scientific Corporation | |
| Prospective Study on Oncologic Cerebral Imagery Contribution by 18F-FDOPA Position Emission Tomography (PET) | NCT02022800 | Glioma Cerebral Metast... | PET 18FDOPA | 18 Years - 85 Years | Centre Antoine Lacassagne | |
| Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma | NCT02062827 | Recurrent Gliob... Progressive Gli... Anaplastic Astr... | M032 (NSC 73397... | 18 Years - | University of Alabama at Birmingham | |
| Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas | NCT04346472 | Low-grade Gliom... | Repeated Measur... | 18 Years - | University Hospital, Montpellier | |
| AMG 102 and Avastin for Recurrent Malignant Glioma | NCT01113398 | Glioblastoma Mu... Gliosarcoma | AMG 102 Avastin | 18 Years - | Duke University | |
| Non Invasive IDentification of Gliomas With IDH1 Mutation | NCT01703962 | Non Invasive Di... | 18 Years - 65 Years | Institut National de la Santé Et de la Recherche Médicale, France | ||
| Tumor Treating Fields for the Treatment of Brainstem Gliomas | NCT05310448 | Glioma | Optune device | 18 Years - | Emory University | |
| A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab | NCT01743950 | Glioma | Bevacizumab PRDR | 18 Years - | University of Wisconsin, Madison | |
| Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption | NCT03551249 | Glioma Glioblastoma | Focused ultraso... | 18 Years - 80 Years | InSightec | |
| A Case-Referent Study of Brain Tumors in Adults | NCT00339300 | Brain Tumors | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Biomarker-based Algorithm for Diagnosis of Glioma | NCT04194593 | Glioma | PCR (Polymerase... | 18 Years - | Hospices Civils de Lyon | |
| Natural History of Patients With Brain and Spinal Cord Tumors | NCT00009035 | Astrocytoma Oligodendroglio... Glioblastoma Glioma Anaplastic Glio... | 1 Year - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab | NCT06011109 | Glioma Glioblastoma Mu... | APG-157 | 19 Years - | Aveta Biomics, Inc. |
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