Spots Global Cancer Trial Database for Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas
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Trial Identification
Brief Title: Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas
Official Title: Survival Significance and Clinical Characteristics of Molecular Pathology and Genetic Variation in Brain Gliomas
Study ID: NCT04216537
Study Description
Brief Summary: This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic data. This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Detailed Description: Precise classification based on molecular and genetic biomarkers/subgroups for gliomas is challenging. This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and genetic data (Whole exome sequencing, RNA sequencing, proteomics, etc). This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Eligibility
Minimum Age: 1 Year
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Contact Details
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