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Brief Title: Therapy Optimisation for the Treatment of Hairy Cell Leukemia
Official Title: Therapy Optimisation for the Treatment of Hairy Cell Leukemia
Study ID: NCT02131753
Brief Summary: The trial will test the effectiveness and toxicity of subcutaneous treatment with one cycle of cladribine in patients with hairy cell leukemia requiring treatment. They have to be untreated so far or may be pretreated with alpha-interferon.
Detailed Description: Evaluation of remission status will take place 4 months after treatment. In addition, it will be tested whether patients with non-optimal response will have a benefit from a second cycle of cladribine. Non-optimal response is: patients with detectable residual disease; achievement of partial remission or detectable residual infiltration in the bone marrow.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Community based hemato-oncology medical office, Ansbach, , Germany
Community based hemato-oncology medical office, Aschaffenburg, , Germany
Rhön-Saale-Klinik gGmbH, Bad Neustadt An Der Saale, , Germany
Community based hemato-oncology medical office, Berlin, , Germany
Charité - Universitätsmedizin Berlin, Berlin, , Germany
Community based hemato-oncology medical office, Bremen, , Germany
Community based hemato-oncology medical office, Celle, , Germany
Community based hemato-oncology medical office, Cottbus, , Germany
Community based hemato-oncology medical office, Darmstadt, , Germany
Community based hemato-oncology medical office, Dresden, , Germany
Community based hemato-oncology medical office, Duisburg, , Germany
Klinik Duisburg-West, Duisburg, , Germany
Universitätsklinik Düsseldorf, Düsseldorf, , Germany
Community based hemato-oncology medical office, Ehingen, , Germany
Community based hemato-oncology medical office, Erlangen, , Germany
Community based hemato-oncology medical office, Frankfurt, , Germany
Krankenhaus Nordwest, Frankfurt, , Germany
Community based hemato-oncology medical office, Freiburg, , Germany
Community based hemato-oncology medical office, Friedrichshafen, , Germany
Community based hemato-oncology medical office, Fürth, , Germany
Community based hemato-oncology medical office, Germering, , Germany
Community based hemato-oncology medical office, Gießen, , Germany
University Clinic | Medicinal Clinic IV, Gießen, , Germany
St.-Marien-Hospital, Hagen, , Germany
Community based hemato-oncology medical office, Halle, , Germany
Evangelisches Krankenhaus, Hamm, , Germany
Community based hemato-oncology medical office, Hanau, , Germany
Community based hemato-oncology medical office, Heidelberg, , Germany
Community based hemato-oncology medical office, Herne, , Germany
Marienkrankenhaus, Herne, , Germany
Community based hemato-oncology medical office, Homberg, , Germany
Community based hemato-oncology medical office, Kaiserslautern, , Germany
Städtisches Klinikum, Karlsruhe, , Germany
Community based hemato-oncology medical office, Kassel, , Germany
Klinikum Kempten-Oberallgäu, Kempten, , Germany
Community based hemato-oncology medical office, Koblenz, , Germany
Community based hemato-oncology medical office, Krefeld, , Germany
Community based hemato-oncology medical office, Kronach, , Germany
Community based hemato-oncology medical office, Landau, , Germany
Community based hemato-oncology medical office, Landshut, , Germany
Community based hemato-oncology medical office, Landshut, , Germany
Klinikum Leverkusen GmbH, Leverkusen, , Germany
St. Marienkrankenhaus, Ludwigshafen, , Germany
Community based hemato-oncology medical office, Lüdenscheid, , Germany
Universitätsklinik Mainz, Mainz, , Germany
Community based hemato-oncology medical office, Marburg, , Germany
Community based hemato-oncology medical office, Mönchengladbach, , Germany
Community based hemato-oncology medical office, München, , Germany
University Clinic Großhadern, München, , Germany
Community based hemato-oncology medical office, Neumarkt, , Germany
Community based hemato-oncology medical office, Nürnberg, , Germany
Community based hemato-oncology medical office, Nürnberg, , Germany
St. Clemens Hospital, Oberhausen, , Germany
St. Martinus-Hospital, Olpe, , Germany
Community based hemato-oncology medical office, Osnabrück, , Germany
St. Josefs-Krankenhaus, Potsdam, , Germany
Community based hemato-oncology medical office, Rehling, , Germany
Community based hemato-oncology medical office, Rüsselsheim, , Germany
Caritas Klinik St. Theresia, Saarbrücken, , Germany
Community based hemato-oncology medical office, Schkeuditz, , Germany
Kreiskrankenhaus Schotten, Schotten, , Germany
Community based hemato-oncology medical office, Schweinfurt, , Germany
Community based hemato-oncology medical office, Siegen, , Germany
St.-Marien-Krankenhaus, Siegen, , Germany
Diakonie - Klinikum Stuttgart, Stuttgart, , Germany
Community based hemato-oncology medical office, Trier, , Germany
Community based hemato-oncology medical office, Tübingen, , Germany
University Clinic Ulm, Ulm, , Germany
Städtisches Krankenhaus Villingen, Villingen-Schwenningen, , Germany
Community based hemato-oncology medical office, Weilheim, , Germany
Sophien- und Hufeland Klinikum, Weimar, , Germany
Asklepios Nordseeklinik, Westerland, , Germany
Community based hemato-oncology medical office, Wiesbaden, , Germany
Dr. Horst-Schmidt-Kliniken, Wiesbaden, , Germany
Community based hemato-oncology medical office, Wilhelmshaven, , Germany
Community based hemato-oncology medical office, Wolfsburg, , Germany
Name: Mathias J Rummel, Prof. Dr.
Affiliation: Justus-Liebig-University | University Hospital | Medicinal Clinic IV
Role: PRINCIPAL_INVESTIGATOR