Spots Global Cancer Trial Database for untreated
Every month we try and update this database with for untreated cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Trial With Azacitidine in Newly Diagnosed Acute Myelogenous Leukemia (AML) Veterans Administration (VA) Elderly Patients Not Eligible for Standard Induction Therapy | NCT00728520 | Acute Myeloid L... Elderly | Azacitidine | 60 Years - | Kansas City Veteran Affairs Medical Center | |
| Therapy Optimisation for the Treatment of Hairy Cell Leukemia | NCT02131753 | Hairy Cell Leuk... | Cladribine s.c.... | 18 Years - 90 Years | University of Giessen | |
| Hydroxychloroquine in Untreated B-CLL Patients | NCT00771056 | B-Cell Chronic ... | Hydroxychloroqu... | 18 Years - | Northwell Health | |
| Melanoma Biomarker Study | NCT00348088 | Metastatic Mela... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | ||
| Ofatumumab for High-Risk Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) | NCT01243190 | Chronic Lymphoc... | Ofatumumab | 18 Years - | M.D. Anderson Cancer Center | |
| Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer | NCT00613626 | Small Cell Lung... | Cisplatin Etoposide Placebo ZD6474 | 18 Years - | Hoosier Cancer Research Network | |
| Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN | NCT01305772 | Squamous Cell C... | Panitumumab Surgery Radiation Thera... | 18 Years - | Duke University | |
| Pembrolizumab in Combination With Cisplatin and Intensity Modulated Radiotherapy (IMRT) in Head and Neck Cancer | NCT02777385 | Head and Neck S... | Pembrolizumab Cisplatin IMRT | 18 Years - | University of Pittsburgh | |
| Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer | NCT04163900 | Biliary Tract C... | NUC-1031 Gemcitabine Cisplatin | 18 Years - | NuCana plc | |
| Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL) | NCT00628238 | Chronic Lymphoc... CLL Untreated Front-line First-Line Initial Therapy | Lenalidomide an... Lenalidomide an... | - | Chronic Lymphocytic Leukemia Research Consortium | |
| Chemotherapy Combined With Radiotherapy vs Chemotherapy Alone for Distant Metastatic Nasopharyngeal Carcinoma | NCT02111460 | Nasopharyngeal ... | Loco-regional R... | 18 Years - 65 Years | Sun Yat-sen University | |
| Rituximab and Involved Field Radiotherapy in Early Stage Follicular Lymphoma | NCT00509184 | Lymphoma, Malig... | Rituximab | 18 Years - 75 Years | Heidelberg University | |
| Randomized, Open-label, Two-arms, Phase III Comparative Study Assessing the Role of Involved Mediastinal Radiotherapy After Rituximab Containing Chemotherapy Regimens to Patients With Newly Diagnosed Primary Mediastinal Large B-Cell Lymphoma | NCT01599559 | Primary Mediast... | observation 3D-Conformal Ra... | 18 Years - | International Extranodal Lymphoma Study Group (IELSG) | |
| Lenalidomide Plus Bendamustine and Rituximab for Untreated CLL/SLL | NCT01400685 | Chronic Lymphoc... Small Lymphocyt... B Chronic Lymph... | Lenalidomide Bendamustine Rituximab | 18 Years - 80 Years | Massachusetts General Hospital | |
| Study to Evaluate the Efficacy and Safety of FOLFOX-4 Plus Cetuximab Versus UFOX Plus Cetuximab. | NCT00439517 | Previously Untr... | UFOX + Cetuxima... FOLFOX4 + Cetux... | 18 Years - | Merck KGaA, Darmstadt, Germany | |
| Botensilimab and Balstilimab Optimization in Colorectal Cancer | NCT06268015 | Colorectal Canc... | Botensilimab Balstilimab Oxaliplatin Leucovorin Fluorouracil Bevacizumab Panitumumab | 18 Years - | Duke University | |
| Sequential Chemotherapy and Lenalidomide Followed by Rituximab and Lenalidomide Maintenance for Untreated Mantle Cell Lymphoma | NCT02633137 | Mantle Cell Lym... Untreated | Lenalidomide R-CHOP high-dose cytar... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome | NCT01873703 | Myelodysplastic... | pracinostat Placebo Azacitidine | 18 Years - | Helsinn Healthcare SA | |
| FCM-R (Fludarabine, Cyclophosphamide, Mitoxantrone, Rituximab) in Previously Untreated Patients With Chronic Lymphocytic Leukemia (CLL) < 70 Years | NCT00254410 | Chronic Lymphoc... | Fludarabine Cyclophosphamid... Mitoxantrone Rituximab Filgrastim | - 70 Years | M.D. Anderson Cancer Center | |
| Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia | NCT00748189 | Leukaemia, Lymp... | chlorambucil, t... ofatumumab (GSK... | 18 Years - | Novartis | |
| Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia | NCT00748189 | Leukaemia, Lymp... | chlorambucil, t... ofatumumab (GSK... | 18 Years - | Novartis | |
| Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL) | NCT00628238 | Chronic Lymphoc... CLL Untreated Front-line First-Line Initial Therapy | Lenalidomide an... Lenalidomide an... | - | Chronic Lymphocytic Leukemia Research Consortium | |
| Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With Metastatic Pancreatic Cancer | NCT01844817 | Pancreatic Canc... | OGX-427 Placebo | 18 Years - | SCRI Development Innovations, LLC | |
| Acalabrutinib-Lenalidomide-Rituximab in Patients With Untreated MCL | NCT03863184 | Mantle Cell Lym... | Acalabrutinib Lenalidomide Rituximab | 18 Years - | Weill Medical College of Cornell University | |
| CHOP and Campath-1H in Previously Untreated Aggressive T/NK-Cell Lymphomas | NCT00323323 | Non-Hodgkin's L... | CHOP Alemtuzumab Plasma Samples | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Lenalidomide Dose Escalation Combined With Rituximab/Fludarabine in Untreated CLL | NCT00738829 | Leukemia, Lymph... | Lenalidomide Fludarabine Rituximab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer. | NCT01229813 | Colorectal Canc... | bevacizumab, er... bevacizumab bevacizumab low dose capeci... | 18 Years - | Lund University Hospital | |
| LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic Cancer | NCT01485744 | Pancreatic Canc... | LDE225; Fluorou... | 18 Years - 72 Years | Massachusetts General Hospital | |
| Carfilzomib, Rituximab and Dexamethasone in Waldenstrom's Macroglobulinemia | NCT01470196 | Waldenstrom's M... | Dexamethasone Carfilzomib Rituximab | 18 Years - | Dana-Farber Cancer Institute | |
| Study of Sapacitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS) | NCT01211457 | Acute Myeloid L... Myelodysplastic... | sapacitabine an... sapacitabine an... | 18 Years - | Cyclacel Pharmaceuticals, Inc. | |
| Fludarabine, Rituximab, and Lenalidomide in Minimally Treated/Untreated Patients With Chronic Lymphocytic Leukemia (CLL) | NCT00536341 | Chronic Lymphoc... | lenalidomide Rituximab Fludarabine | 18 Years - | SCRI Development Innovations, LLC | |
| Ofatumumab for High-Risk Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) | NCT01243190 | Chronic Lymphoc... | Ofatumumab | 18 Years - | M.D. Anderson Cancer Center | |
| Lenalidomide in Combination With CHOP in Patients With Untreated PTCL | NCT04423926 | PTCL, NOS AITL ALK- ALCL Phase III-IV AL... EATL | Lenalidomide Cyclophosphamid... Doxorubicin Vincristine Prednisolone | 18 Years - 70 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer | NCT01453153 | Stage IV Pancre... | Gemcitabine PEGPH20 Placebo | 18 Years - | Halozyme Therapeutics | |
| Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer. | NCT01229813 | Colorectal Canc... | bevacizumab, er... bevacizumab bevacizumab low dose capeci... | 18 Years - | Lund University Hospital | |
| LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic Cancer | NCT01485744 | Pancreatic Canc... | LDE225; Fluorou... | 18 Years - 72 Years | Massachusetts General Hospital | |
| Lenalidomide Dose Escalation Combined With Rituximab/Fludarabine in Untreated CLL | NCT00738829 | Leukemia, Lymph... | Lenalidomide Fludarabine Rituximab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome | NCT01873703 | Myelodysplastic... | pracinostat Placebo Azacitidine | 18 Years - | Helsinn Healthcare SA | |
| Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN | NCT01305772 | Squamous Cell C... | Panitumumab Surgery Radiation Thera... | 18 Years - | Duke University | |
| Ixabepilone and Carboplatin +/- Bevacizumab in Advanced Non-Small-Cell Lung Cancer | NCT00741988 | Non-Small Cell ... | Ixabepilone Carboplatin Bevacizumab | 18 Years - | SCRI Development Innovations, LLC | |
| Sequential Chemotherapy and Lenalidomide Followed by Rituximab and Lenalidomide Maintenance for Untreated Mantle Cell Lymphoma | NCT02633137 | Mantle Cell Lym... Untreated | Lenalidomide R-CHOP high-dose cytar... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Botensilimab and Balstilimab Optimization in Colorectal Cancer | NCT06268015 | Colorectal Canc... | Botensilimab Balstilimab Oxaliplatin Leucovorin Fluorouracil Bevacizumab Panitumumab | 18 Years - | Duke University | |
| Randomized, Open-label, Two-arms, Phase III Comparative Study Assessing the Role of Involved Mediastinal Radiotherapy After Rituximab Containing Chemotherapy Regimens to Patients With Newly Diagnosed Primary Mediastinal Large B-Cell Lymphoma | NCT01599559 | Primary Mediast... | observation 3D-Conformal Ra... | 18 Years - | International Extranodal Lymphoma Study Group (IELSG) |
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