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Spots Global Cancer Trial Database for Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer

Official Title: A Phase II Trial of Carboplatin Plus Paclitaxel in the Treatment of Locally Recurrent or Metastatic Nasopharyngeal Carcinoma

Study ID: NCT00003206

Study Description

Brief Summary: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of carboplatin and paclitaxel in treating patients with locally recurrent or metastatic nasopharyngeal cancer.

Detailed Description: OBJECTIVES: I. Estimate the response and toxicity of carboplatin in combination with paclitaxel in patients with locally recurrent or metastatic nasopharyngeal carcinoma. OUTLINE: Patients receive paclitaxel IV over 3 hours followed by carboplatin IV over 30 minutes. This cycle is repeated every 3 weeks. Patients may receive 6-8 cycles of therapy in the absence of toxicity and disease progression. Patients are followed every 3 months for the first 2 years, every 6 months for the next 3 years, and yearly thereafter. PROJECTED ACCRUAL: 30 eligible patients will be accrued in approximately 18 months.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Veterans Affairs Medical Center - Palo Alto, Palo Alto, California, United States

Stanford University Medical Center, Stanford, California, United States

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Emory University Hospital - Atlanta, Atlanta, Georgia, United States

Veterans Affairs Medical Center - Atlanta (Decatur), Decatur, Georgia, United States

Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States

Veterans Affairs Medical Center - Chicago (Lakeside), Chicago, Illinois, United States

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

CCOP - Cedar Rapids Oncology Project, Cedar Rapids, Iowa, United States

CCOP - Kalamazoo, Kalamazoo, Michigan, United States

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, United States

CCOP - Northern New Jersey, Hackensack, New Jersey, United States

University of Rochester Cancer Center, Rochester, New York, United States

Ireland Cancer Center, Cleveland, Ohio, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Vanderbilt Cancer Center, Nashville, Tennessee, United States

Pretoria Academic Hospital, Pretoria, , South Africa

Contact Details

Name: Barbara A. Murphy, MD

Affiliation: Vanderbilt-Ingram Cancer Center

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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