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Spots Global Cancer Trial Database for Central Pain Syndrome in Survivors of Head and Neck Cancer

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Trial Identification

Brief Title: Central Pain Syndrome in Survivors of Head and Neck Cancer

Official Title: Characterization of Central Pain Syndrome in Survivors of Head and Neck Cancer

Study ID: NCT04128267

Study Description

Brief Summary: This is a cross-sectional pilot study of head and neck cancer survivors who have completed multi-modal treatment to assess and characterize the presence of distinct pain syndromes.

Detailed Description: Primary objectives: * To correlate structural and functional MRI signature with one of three pain phenotypes in head and neck cancer survivors: 1) no pain, 2) central pain, and 3) nociceptive pain. * To correlate the presence of chronic systemic symptoms with pain phenotype Exploratory objectives: - DNA, RNA, and plasma will be collected for genomic, transcriptomic, and proteomic studies. Results will be vertically integrated along with the results of clinical studies described within this protocol to identify targets for future correlative studies.

Keywords

Eligibility

Minimum Age: 21 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

Contact Details

Name: Dianne Lou, MD, PhD

Affiliation: Vanderbilt Medical Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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