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Brief Title: Central Pain Syndrome in Survivors of Head and Neck Cancer
Official Title: Characterization of Central Pain Syndrome in Survivors of Head and Neck Cancer
Study ID: NCT04128267
Brief Summary: This is a cross-sectional pilot study of head and neck cancer survivors who have completed multi-modal treatment to assess and characterize the presence of distinct pain syndromes.
Detailed Description: Primary objectives: * To correlate structural and functional MRI signature with one of three pain phenotypes in head and neck cancer survivors: 1) no pain, 2) central pain, and 3) nociceptive pain. * To correlate the presence of chronic systemic symptoms with pain phenotype Exploratory objectives: - DNA, RNA, and plasma will be collected for genomic, transcriptomic, and proteomic studies. Results will be vertically integrated along with the results of clinical studies described within this protocol to identify targets for future correlative studies.
Minimum Age: 21 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Name: Dianne Lou, MD, PhD
Affiliation: Vanderbilt Medical Center
Role: PRINCIPAL_INVESTIGATOR