Spots Global Cancer Trial Database for Gene Expression Profiles in Predicting Survival of Patients With Head and Neck Cancer

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Trial Identification

Brief Title: Gene Expression Profiles in Predicting Survival of Patients With Head and Neck Cancer

Official Title: Survival Prediction in HNSCC Based on Gene Expression Profiles From FFPE Tissues

Study ID: NCT00897052

Conditions

Head and Neck Cancer

Interventions

microarray analysis

laboratory biomarker analysis

Study Description

Brief Summary: RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict survival of patients with head and neck cancer. PURPOSE: This laboratory study is assessing gene expression profiles in predicting survival of patients with head and neck cancer.

Detailed Description: OBJECTIVES: * Identify gene expression profiles associated with survival by DNA microarray assay analysis using RNA from formalin-fixed paraffin-embedded tissue samples from patients with squamous cell carcinoma of the head and neck treated on clinical trial RTOG-9501. OUTLINE: Formalin-fixed paraffin-embedded tissue samples are analyzed by DNA microarray analysis for gene expression profiling.