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Brief Title: Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
Official Title: Head and Neck Tumor Tissue Repository and Clinical Database
Study ID: NCT00898638
Brief Summary: RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.
Detailed Description: OBJECTIVES: * Maintain and update a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer. * Develop a repository of biospecimens from these patients. OUTLINE: Tumor tissue samples and/or bronchial washings are collected from patients undergoing planned surgery and/or bronchoscopy, respectively. Buccal swabs and/or mouthwash samples and saliva samples are collected. Patients also undergo blood sample collection at baseline and then every 2-6 months thereafter. Healthy participants contribute blood samples, buccal swabs, and mouthwash samples at baseline only. Information about medical and family history and cancer risk factors is also collected. PROJECTED ACCRUAL: No limit. FOLLOW UP: Indefinite, until date of death or lost to follow up.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville, Tennessee, United States
Vanderbilt-Ingram Cancer Center at Franklin, Nashville, Tennessee, United States
Veterans Affairs Medical Center - Nashville, Nashville, Tennessee, United States
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Name: Eben Rosenthal, MD
Affiliation: Vanderbilt University Medical Center
Role: PRINCIPAL_INVESTIGATOR