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Spots Global Cancer Trial Database for Gastric Pull up Versus Free Flap Reconstruction for Laryngo-pharyngeal Defects

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Trial Identification

Brief Title: Gastric Pull up Versus Free Flap Reconstruction for Laryngo-pharyngeal Defects

Official Title: Gastric Pull up Versus Free Flaps Reconstruction (Anterolateral Thigh and Radial Forearm Free Flap) for Laryngo-pharyngeal Defects: A Prospective Randomized Trial

Study ID: NCT03171558

Study Description

Brief Summary: This study will compare the gastric pull up (GPU) with the free flap \[(specifically, anterolateral thigh (ALT) and radial forearm free flap (RFFF)\] techniques used in the reconstruction of alimentary tracts in patients who require laryngectomy and circumferential pharyngectomy for carcinoma resection. These two interventions will be compared by block randomizing 20 patients based on history of failed chemoradiation to undergo either ALT or RFFF. The primary outcome will be the type and number of postoperative complications. The secondary outcomes will include swallowing function, speech, and quality of life measures along with cancer specific endpoints.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Vancouver General Hospital, Vancouver, British Columbia, Canada

Contact Details

Name: Prisman Eitan, MD, FRCSC

Affiliation: University of British Columbia

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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