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Brief Title: Study of Pembrolizumab Combined With Anlotinib in the First Line Therapy for R/M HNSCC With CPS≥1
Official Title: A Prospective Clinical Study to Evaluate the Efficacy and Safety of Pembrolizumab Combined With Anlotinib in First-line Treatment for Patients With of R/M HNSCC PD-L1 CPS≥1
Study ID: NCT04999800
Brief Summary: This trial is main evaluate the efficacy and safety of Pembrolizumab combined with Anlotinib in the first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma with CPS≥1
Detailed Description: This test is a single-center, prospective phase II clinical research, plan included in 20 cases of eligible subjects, assessment in China PD-L1 CPS≥1 or more recurrent and/or metastatic head and neck squamous cell carcinoma patients, Pembrolizumab combined with Anlotinib for the initial curative effect, adverse reaction and safety, provide the basis for subsequent clinical trials
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
National Cancer Center/Cancer Hospitial,Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing, China
Name: Yuankai Shi, MD
Affiliation: Cancer Institute/Hospital, Chinese Academy of Medical Sciences&Peking Union Medical college
Role: PRINCIPAL_INVESTIGATOR