Spots Global Cancer Trial Database for Hearing Loss and Complaint in Patients With Head and Neck Cancer Treated With Radiotherapy

Study Description

Brief Summary: Hypothesis: Treatment for head and neck tumors often involve methods that affect the auditory system and cause hearing loss. Neck dissection negatively impacts the lymphatic drainage, chemotherapy uses ototoxic drugs, radiotherapy affects blood flow and tissue radiation is toxic to the ear and may lead to hearing losses of various types and degrees. Objective: To investigate occurrences of hearing loss and complaints among patients with head and neck tumors who underwent radiotherapy. Study design: Prospective, case-control study. Setting: Tertiary care center hospital. Subjects and Methods: 282 subjects were evaluated, 141 with head and neck tumors and 141 as an age-matched control group. The controls had never undergone oncological treatment that put their hearing at risk. All subjects underwent audiological evaluation, including the HHIE questionnaire, pure tone audiometry, speech audiometry and immittance audiometry. The radiation dose received by the auditory system was calculated based on the percentage of the external auditory canal included in the radiation field.

Detailed Description:

Keywords

Eligibility

Minimum Age: 11 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Contact Details

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