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Brief Title: A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy
Official Title: A Multicenter, Randomized Trial Comparing The Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Subjects With Hematological Malignancy
Study ID: NCT02895529
Brief Summary: The purpose of this study is to investigate the hypothesis that the efficacy of intravenous (IV) itraconazole followed by oral itraconazole is non-inferior to that of intravenous caspofungin as empiric therapy for suspected fungal infection participants with fever and neutropenia.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Beijign, , China
, Beijing, , China
, Changchun, , China
, Changzhou, , China
, Fuzhou, , China
, Guangzhou, , China
, Guiyang, , China
, Hefei, , China
, Shanghai, , China
, Suzhou, , China
, Tianjin, , China
, Zhengzhou, , China
Name: Xian-Janssen Pharmaceutical Ltd., China Clinical Trial
Affiliation: Xian-Janssen Pharmaceutical Ltd.
Role: STUDY_DIRECTOR