Spots Global Cancer Trial Database for itraconazole
Every month we try and update this database with for itraconazole cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Single Ascending Dose, First-in-Human Study on Safety, Tolerability and Pharmacokinetics of BAY1161116 | NCT03119077 | Polycystic Ovar... | BAY1161116 Placebo Itraconazole | 45 Years - 65 Years | Bayer | |
| Itraconazole in Advanced Ovarian Cancer | NCT05591560 | Ovarian Carcino... | Itraconazole ca... Placebo | 18 Years - 65 Years | Tanta University | |
| A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer | NCT05563766 | Esophageal Aden... Esophageal Squa... Gastroesophagea... | Itraconazole | 18 Years - | VA Office of Research and Development | |
| Neoadjuvant Itraconazole in Non-small Cell Lung Cancer | NCT02357836 | Non-small Cell ... | Itraconazole | 18 Years - | University of Texas Southwestern Medical Center | |
| A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State | NCT02608034 | Metastatic Mela... | Itraconazole Rifampin Vemurafenib | 18 Years - | Genentech, Inc. | |
| Observational Study Investigating the Response Rate of Itraconazole Injection in Treating Immunocompromised Patients | NCT01060462 | Hematological M... Neutropenia Fever | Pts. w/ neutrop... | 18 Years - | Janssen Korea, Ltd., Korea | |
| Topical Itraconazole in Treating Patients With Basal Cell Cancer | NCT02735356 | Skin Basal Cell... | Itraconazole Placebo | 18 Years - | Stanford University | |
| Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects | NCT06348290 | Solid Tumor, Ad... | JMKX001899 Itraconazole Midazolam Rifampin dextromethorpha... Rosuvastatin digoxin | 18 Years - 45 Years | Jemincare | |
| Study of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapy | NCT01450683 | Prostate Cancer Prostatic Neopl... Castrate-resist... Androgen-insens... Hormone-refract... Metastatic Dise... | Itraconazole | 18 Years - | Stanford University | |
| Itraconazole in Non Small Cell Lung Cancer | NCT03664115 | Lung Cancer | Itraconazole 20... Chemotherapy | 18 Years - | Ain Shams University | |
| Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours | NCT01772563 | Neoplasms | volasertib itraconazole | 18 Years - 70 Years | Boehringer Ingelheim | |
| Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole | NCT02824042 | Medical Oncolog... | Anetumab ravtan... Itraconazole | 18 Years - | Bayer | |
| Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects | NCT06348290 | Solid Tumor, Ad... | JMKX001899 Itraconazole Midazolam Rifampin dextromethorpha... Rosuvastatin digoxin | 18 Years - 45 Years | Jemincare | |
| CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer | NCT04481100 | Esophageal Neop... Esophageal Dise... Esophageal Squa... | itraconazole | 18 Years - 75 Years | Hangzhou Cancer Hospital | |
| To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours | NCT01900028 | Solid Tumours | Pharmacokinetic... Olaparib tablet... Itraconazole | 18 Years - 130 Years | AstraZeneca | |
| Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer | NCT04018872 | Esophagus Adeno... Esophagus Squam... Gastroesophagea... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer | NCT04537715 | All Malignancie... Advanced Malign... Hematologic Mal... Solid Tumor Follicular Lymp... Non-Hodgkin Lym... Diffuse Large B... Epithelioid Sar... Synovial Sarcom... Renal Medullary... Mesothelioma Rhabdoid Tumor | Tazemetostat Itraconazole Tazemetostat Rifampin | 18 Years - | Ipsen | |
| A Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body | NCT04712396 | Healthy Volunte... | Capivasertib Itraconazole | 18 Years - 58 Years | AstraZeneca | |
| A Study of DB-1303 in Advanced/Metastatic Solid Tumors | NCT05150691 | HER2-positive A... | DB-1303 Pertuzumab Inje... Ritonavir Itraconazole | 18 Years - | DualityBio Inc. | |
| Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours | NCT01772563 | Neoplasms | volasertib itraconazole | 18 Years - 70 Years | Boehringer Ingelheim | |
| A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib | NCT04959266 | Advanced Solid ... | Adavosertib Itraconazole Rifampicin Omeprazole | 18 Years - 130 Years | AstraZeneca | |
| A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor | NCT05372367 | Solid Tumors | BI 907828 Rifampicin Itraconazole | 18 Years - 70 Years | Boehringer Ingelheim | |
| Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors | NCT02122770 | Advanced Solid ... | MLN4924 Fluconazole Itraconazole Docetaxel Carboplatin Paclitaxel | 18 Years - | Takeda | |
| A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor | NCT05372367 | Solid Tumors | BI 907828 Rifampicin Itraconazole | 18 Years - 70 Years | Boehringer Ingelheim | |
| Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin. | NCT03972748 | Basal Cell Carc... Hedgehog Pathwa... | Itraconazole 20... | 18 Years - | Hospital de Clinicas de Porto Alegre | |
| A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential | NCT02706535 | Drug Interactio... Neoplasms | GSK525762 Besyl... Itraconazole 20... Rifampicin 300 ... | 18 Years - 70 Years | GlaxoSmithKline | |
| Phase Ib/II Study Evaluating Orteronel (Without Prednisone) Combined With Itraconazole In Men With Castration-Resistant Prostate Cancer (CRPC) | NCT02054793 | Prostate Cancer Castration-resi... | Itraconazole Orteronel | 18 Years - | Johns Hopkins University | |
| Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection | NCT01198236 | Invasive Fungal... | Itraconazole | 18 Years - 65 Years | Zhejiang University | |
| Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients | NCT02749513 | Esophageal Canc... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation | NCT00336531 | Neuroblastoma Brain Tumor Retinoblastoma Wilms Tumor Mycoses | itraconazole | - 15 Years | Samsung Medical Center | |
| Itraconazole in Treating Patients With Biochemically Relapsed Prostate Cancer | NCT01787331 | Prostate Adenoc... Recurrent Prost... Stage I Prostat... Stage II Prosta... Stage III Prost... | Itraconazole Laboratory Biom... Pharmacological... | 18 Years - | University of California, San Francisco | |
| Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors | NCT02122770 | Advanced Solid ... | MLN4924 Fluconazole Itraconazole Docetaxel Carboplatin Paclitaxel | 18 Years - | Takeda | |
| ATRA, Celecoxib, and Itraconazole as Maintenance | NCT02401295 | Relapsed Multip... | ATRA Celecoxib Itraconazole | 18 Years - 75 Years | University of Iowa | |
| A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy | NCT02895529 | Hematologic Neo... | Itraconazole Caspofungin | 18 Years - | Xian-Janssen Pharmaceutical Ltd. | |
| Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients | NCT02749513 | Esophageal Canc... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy | NCT02895529 | Hematologic Neo... | Itraconazole Caspofungin | 18 Years - | Xian-Janssen Pharmaceutical Ltd. | |
| Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS) | NCT02354261 | Basal Cell Carc... | SUBA-Itraconazo... | 18 Years - | HedgePath Pharmaceuticals, Inc. | |
| Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva) | NCT02157883 | Advanced Non Sm... Advanced (Inope... | Pharmacokinetic... AZD9291 Itraconazole | 18 Years - 99 Years | AstraZeneca | |
| A Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body | NCT04712396 | Healthy Volunte... | Capivasertib Itraconazole | 18 Years - 58 Years | AstraZeneca | |
| Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLC | NCT00769600 | Recurrent Non S... | Itraconazole Pemetrexed | 18 Years - 100 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Study of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapy | NCT01450683 | Prostate Cancer Prostatic Neopl... Castrate-resist... Androgen-insens... Hormone-refract... Metastatic Dise... | Itraconazole | 18 Years - | Stanford University | |
| COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients | NCT02253420 | Medical Oncolog... | Copanlisib (BAY... Itraconazole Rifampin Copanlisib (BAY... | 18 Years - | Bayer | |
| The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors | NCT04312282 | Advanced Solid ... | Tesetaxel Tesetaxel Itraconazole Rifampin | 18 Years - | Odonate Therapeutics, Inc. | |
| Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva) | NCT02157883 | Advanced Non Sm... Advanced (Inope... | Pharmacokinetic... AZD9291 Itraconazole | 18 Years - 99 Years | AstraZeneca | |
| To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers | NCT02093728 | Solid Tumours | selumetinib itraconazole itraconazole selumetinib selumetinib fluconazole fluconazole selumetinib | 18 Years - 45 Years | AstraZeneca | |
| A Study of Empirical Antifungal Therapy With Itraconazole | NCT01706562 | Neutropenia | Itraconazole | 20 Years - | Janssen Korea, Ltd., Korea | |
| A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential | NCT02706535 | Drug Interactio... Neoplasms | GSK525762 Besyl... Itraconazole 20... Rifampicin 300 ... | 18 Years - 70 Years | GlaxoSmithKline | |
| Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer | NCT04018872 | Esophagus Adeno... Esophagus Squam... Gastroesophagea... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| The Relationship of Defeverscence and Itraconazole Plasma Level Study in Immunocompromised Participants | NCT01021683 | Hematologic Neo... Neutropenia Fever | Itraconazole | 20 Years - | Janssen Korea, Ltd., Korea | |
| A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors | NCT03077607 | Advanced Solid ... | Talazoparib Itraconazole Rifampin | 18 Years - | Pfizer | |
| A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects | NCT03346837 | Malignancies Mu... | BMS-986205 Itraconazole Rifampin | 18 Years - 50 Years | Bristol-Myers Squibb | |
| The Relationship of Defeverscence and Itraconazole Plasma Level Study in Immunocompromised Participants | NCT01021683 | Hematologic Neo... Neutropenia Fever | Itraconazole | 20 Years - | Janssen Korea, Ltd., Korea | |
| AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia | NCT02675452 | Relapsed or Ref... Relapsed or Ref... | AMG 176 Azacitidine Itraconazole | 18 Years - 85 Years | Amgen | |
| ATRA, Celecoxib, and Itraconazole as Maintenance | NCT02401295 | Relapsed Multip... | ATRA Celecoxib Itraconazole | 18 Years - 75 Years | University of Iowa | |
| A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole | NCT05551897 | Healthy Subject... | Camizestrant Itraconazole | 50 Years - 70 Years | AstraZeneca | |
| Neoadjuvant Itraconazole in Non-small Cell Lung Cancer | NCT02357836 | Non-small Cell ... | Itraconazole | 18 Years - | University of Texas Southwestern Medical Center | |
| Topical Itraconazole in the Treatment of Basal Cell Carcinoma | NCT02120677 | Basal Cell Carc... | Itraconazole | 18 Years - 100 Years | Johns Hopkins University | |
| Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer | NCT03994211 | Solid Tumor | pamiparib 60 mg pamiparib 20 mg itraconazole rifampin pamiparib | 18 Years - | BeiGene | |
| A Study of DB-1303 in Advanced/Metastatic Solid Tumors | NCT05150691 | HER2-positive A... | DB-1303 Pertuzumab Inje... Ritonavir Itraconazole | 18 Years - | DualityBio Inc. | |
| Study of DS-8201a for Participants With Advanced Solid Malignant Tumors | NCT03383692 | Neoplasm Metast... | DS-8201a Ritonavir Itraconazole | 20 Years - | Daiichi Sankyo | |
| A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer | NCT00585195 | Non-Small Cell ... Non-Small Cell ... Non-Small Cell ... Systemic Anapla... Advanced Malign... | PF-02341066 Rifampin Itraconazole | 18 Years - | Pfizer | |
| Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas | NCT01108094 | Basal Cell Carc... Skin Cancer | Itraconazole | 18 Years - | Stanford University | |
| A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer | NCT00585195 | Non-Small Cell ... Non-Small Cell ... Non-Small Cell ... Systemic Anapla... Advanced Malign... | PF-02341066 Rifampin Itraconazole | 18 Years - | Pfizer | |
| A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants | NCT06348888 | Advanced Non-sm... EGFR Mutation HER2 Mutation Healthy Volunte... | BAY2927088 Itraconazole Carbamazepine | 18 Years - 55 Years | Bayer | |
| Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors | NCT02122770 | Advanced Solid ... | MLN4924 Fluconazole Itraconazole Docetaxel Carboplatin Paclitaxel | 18 Years - | Takeda | |
| Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer | NCT04018872 | Esophagus Adeno... Esophagus Squam... Gastroesophagea... | Itraconazole | 18 Years - | Dallas VA Medical Center | |
| A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients | NCT05679388 | Prostate Cancer Prostate Cancer... Prostate Adenoc... | Relugolix Pill Ritonavir Itraconazole | 18 Years - | University of Chicago | |
| A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma | NCT02770378 | Glioblastoma | Temozolomide Aprepitant Minocycline Disulfiram Celecoxib Sertraline Captopril Itraconazole Ritonavir Auranofin | 18 Years - | University of Ulm | |
| Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection | NCT01198236 | Invasive Fungal... | Itraconazole | 18 Years - 65 Years | Zhejiang University |
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