Spots Global Cancer Trial Database for Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)
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Trial Identification
Brief Title: Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)
Official Title: A Phase 3 Double-blinded, Two-arm Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma and Complete Radiological Response After Surgical Resection or Local Ablation (KEYNOTE-937)
Study ID: NCT03867084
Conditions
Study Description
Brief Summary: This study will evaluate the safety and efficacy of pembrolizumab (MK-3475) versus placebo as adjuvant therapy in participants with hepatocellular carcinoma (HCC) and complete radiological response after surgical resection or local ablation. The primary hypotheses of this study are that adjuvant pembrolizumab is superior to placebo with respect to: 1) recurrence-free survival (RFS) as assessed by blinded independent central review (BICR); and 2) overall survival (OS).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Banner MD Anderson Cancer Center ( Site 0026), Gilbert, Arizona, United States
The University of Arizona Cancer Center - North Campus ( Site 0039), Tucson, Arizona, United States
City of Hope Medical Center ( Site 0027), Duarte, California, United States
Smilow Cancer Hospital at Yale New Haven ( Site 0042), New Haven, Connecticut, United States
Regional Cancer Center ( Site 0054), Fort Myers, Florida, United States
Indiana University Simon Cancer Center ( Site 0075), Indianapolis, Indiana, United States
University of Iowa ( Site 0067), Iowa City, Iowa, United States
James Graham Brown Cancer Center ( Site 0088), Louisville, Kentucky, United States
University of Louisville ( Site 0059), Louisville, Kentucky, United States
University Medical Center New Orleans ( Site 0014), New Orleans, Louisiana, United States
Massachusetts General Hospital ( Site 0062), Boston, Massachusetts, United States
Boston Medical Center ( Site 0025), Boston, Massachusetts, United States
Beth Israel Deaconess Medical Ctr. ( Site 0033), Boston, Massachusetts, United States
University of Massachusetts Worcester ( Site 0017), Worcester, Massachusetts, United States
Henry Ford Hospital-GI/Hepatology Research ( Site 0047), Detroit, Michigan, United States
University of New Mexico ( Site 0041), Albuquerque, New Mexico, United States
North Shore-Long Island Jewish Health System ( Site 0068), Lake Success, New York, United States
Miami Valley Hospital South ( Site 0093), Centerville, Ohio, United States
University of Cincinnati Medical Center ( Site 0084), Cincinnati, Ohio, United States
ProMedica Flower Hospital ( Site 0090), Sylvania, Ohio, United States
Stephenson Cancer Center ( Site 0045), Oklahoma City, Oklahoma, United States
Vanderbilt Ingram Cancer Center ( Site 0006), Nashville, Tennessee, United States
Baylor Scott & White Medical Center - Temple ( Site 0089), Temple, Texas, United States
Virginia Mason Medical Center ( Site 0028), Seattle, Washington, United States
Hospital Universitario Austral ( Site 0795), Pilar, Buenos Aires, Argentina
Fundación favaloro para la Docencia e Investigación Médica ( Site 0808), Buenos Aires, Caba, Argentina
Hospital Provincial del Centenario ( Site 0794), Rosario, Santa Fe, Argentina
Hospital Aleman ( Site 0806), Buenos Aires, , Argentina
Hospital Italiano ( Site 0793), Buenos Aires, , Argentina
Hospital Britanico de Buenos Aires ( Site 0792), Buenos Aires, , Argentina
Clinica de nefrologia urologia y enfermedades cardiovasculares ( Site 0802), Santa Fe, , Argentina
Royal Prince Alfred Hospital AW ( Site 0225), Camperdown, New South Wales, Australia
Liverpool Hospital ( Site 0226), Liverpool, New South Wales, Australia
Princess Alexandra Hospital ( Site 0228), Woollongabba, Queensland, Australia
Royal Adelaide Hospital ( Site 0234), Adelaide, South Australia, Australia
Monash Health ( Site 0233), Clayton, Victoria, Australia
St Vincents Hospital Melbourne ( Site 0227), Fitzroy, Victoria, Australia
Alfred Health ( Site 0230), Melbourne, Victoria, Australia
Royal Perth Hospital ( Site 0229), Perth, Western Australia, Australia
University Hospital Antwerp (UZA) ( Site 0374), Edegem, Antwerpen, Belgium
Erasme Hospital ( Site 0376), Bruxelles, Bruxelles-Capitale, Region De, Belgium
UZ Gent ( Site 0375), Gent, Oost-Vlaanderen, Belgium
UZ Leuven ( Site 0377), Leuven, Vlaams-Brabant, Belgium
CIONC - Centro Integrado de Oncologia de Curitiba ( Site 0813), Curitiba, Parana, Brazil
Hospital de Cancer de Pernambuco ( Site 0815), Recife, Pernambuco, Brazil
Hospital de Clinicas de Porto Alegre ( Site 0824), Porto Alegre, Rio Grande Do Sul, Brazil
Clinica de Oncologia Reichow ( Site 0818), Blumenau, Santa Catarina, Brazil
Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 0820), Itajai, Santa Catarina, Brazil
Hospital Paulistano ( Site 0829), São Paulo, Sao Paulo, Brazil
Instituto COI de Pesquisa Educacao e Gestao ( Site 0825), Rio de Janeiro, , Brazil
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0826), Sao Paulo, , Brazil
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0828), Sao Paulo, , Brazil
A.C. Camargo Cancer Center ( Site 0827), Sao Paulo, , Brazil
Casa de Saude Santa Marcelina ( Site 0821), Sao Paulo, , Brazil
Complex Cancer Center Plovdiv-First Medical Oncology Department ( Site 0982), Plovdiv, , Bulgaria
Nova Scotia Health Authority QEII-HSC ( Site 0208), Halifax, Nova Scotia, Canada
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0211), Montreal, Quebec, Canada
McGill University Health Centre ( Site 0207), Montreal, Quebec, Canada
Anhui Provincil Hospital South District ( Site 0181), Hefei, Anhui, China
Cancer Hospital Chinese Academy of Medical Sciences ( Site 0156), Beijing, Beijing, China
Peking University People's Hospital ( Site 0191), Beijing, Beijing, China
Beijing Cancer Hospital ( Site 0155), Beijing, Beijing, China
Fujian Provincial Cancer Hospital ( Site 0165), Fuzhou, Fujian, China
900 Hospital of the Joint ( Site 0197), Fuzhou, Fujian, China
Guangdong General Hospital ( Site 0166), Guangzhou, Guangdong, China
Southern Medical University Nanfang Hospital ( Site 0172), Guangzhou, Guangdong, China
Wuhan Union Hospital ( Site 0173), Wuhan, Hubei, China
Hubei Cancer Hospital ( Site 0189), Wuhan, Hubei, China
The Third Xiangya Hospital of Central South University ( Site 0167), Changsha, Hunan, China
Hunan Provincial People Hospital ( Site 0192), Changsha, Hunan, China
Hunan Cancer Hospital ( Site 0168), Changsha, Hunan, China
Fudan University Shanghai Cancer Center ( Site 0161), Shanghai, Shanghai, China
Zhongshan Hospital Fudan University ( Site 0193), Shanghai, Shanghai, China
Renji Hospital Shanghai Jiaotong University School of Medicine ( Site 0174), Shanghai, Shanghai, China
Zhongshan Hospital affiliated to Fudan University ( Site 0153), Shanghai, Shanghai, China
The First Affiliated Hospital of Xi an Jiaotong University ( Site 0164), XI An, Shanxi, China
West China Hospital of Sichuan University ( Site 0162), Chengdu, Sichuan, China
Affiliated Tumor Hospital of Xinjiang Medical University ( Site 0157), Urumqi, Xinjiang, China
Zhejiang Cancer Hospital ( Site 0171), Hangzhou, Zhejiang, China
Herlev Hospital ( Site 0421), Herlev, Hovedstaden, Denmark
Aarhus Universitets hospital ( Site 0420), Aarhus N, Midtjylland, Denmark
Odense Universitets Hospital ( Site 0422), Odense C, Syddanmark, Denmark
HUS Hopital Hautepierre ( Site 0445), Strasbourg, Bas-Rhin, France
Hopital de la Timone ( Site 0442), Marseille, Bouches-du-Rhone, France
CHU Bordeaux Haut-Leveque ( Site 0437), Pessac, Gironde, France
CHU Rangueil ( Site 0441), Toulouse, Haute-Garonne, France
Hopital Beaujon ( Site 0439), Clichy, Hauts-de-Seine, France
CHU Montpellier. ( Site 0443), Montpellier, Herault, France
Hopital Claude Huriez CHRU LILLE ( Site 0440), Lille, Nord, France
Hopital Paul Brousse ( Site 0447), Villejuif, Val-de-Marne, France
SLK-Kliniken Heilbronn GmbH ( Site 0460), Heilbronn, Baden-Wurttemberg, Germany
Universitaetsklinikum Tuebingen ( Site 0466), Tuebingen, Baden-Wurttemberg, Germany
Klinikum rechts der Isar der Technischen Universitaet ( Site 0470), Muenchen, Bayern, Germany
Universitaetsklinikum Wuerzburg ( Site 0468), Wuerzburg, Bayern, Germany
Krankenhaus Nord-West GmbH ( Site 0472), Frankfurt am Main, Hessen, Germany
Universitaetsklinikum Frankfurt ( Site 0467), Frankfurt, Hessen, Germany
Medizinische Hochschule Hannover ( Site 0458), Hannover, Niedersachsen, Germany
Universitaetsklinikum Duesseldorf ( Site 0461), Duesseldorf, Nordrhein-Westfalen, Germany
Universitaetsklinikum Koeln ( Site 0463), Koeln, Nordrhein-Westfalen, Germany
Staedtisches Klinikum Dresden ( Site 0471), Dresden, Sachsen, Germany
Universitatsklinikum Carl Gustav Carus ( Site 0459), Dresden, Sachsen, Germany
Charite - Campus Virchow Klinikum ( Site 0457), Berlin, , Germany
Universitaetsklinikum Hamburg-Eppendorf ( Site 0469), Hamburg, , Germany
Prince of Wales Hospital ( Site 0268), Hong Kong, , Hong Kong
Pamela Youde Nethersole Eastern Hospital ( Site 0271), Hong Kong, , Hong Kong
Queen Mary Hospital ( Site 0267), Hong Kong, , Hong Kong
Tuen Mun Hospital ( Site 0272), Tuen Mun, , Hong Kong
Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 0483), Kecskemét, Bacs-Kiskun, Hungary
SZTE Szent-Gyorgyi Albert Klinikai Kozpont ( Site 0482), Szeged, Csongrad, Hungary
Somogy Megyei Kaposi Mór Oktató Kórház-Oncology center ( Site 0484), Kaposvár, Somogy, Hungary
Semmelweis University ( Site 0480), Budapest, , Hungary
Debreceni Egyetem Klinikai Kozpont Onkologiai Tanszek ( Site 0481), Debrecen, , Hungary
St Vincent's University Hospital ( Site 0498), Dublin, , Ireland
Tallaght University Hospital ( Site 0499), Dublin, , Ireland
Rambam Medical Center ( Site 0524), Haifa, , Israel
Haddassah Medical Organization - Ein Kerem ( Site 0519), Jerusalem, , Israel
Rabin Medical Center ( Site 0520), Petah Tikva, , Israel
Chaim Sheba Medical Center ( Site 0523), Ramat Gan, , Israel
Sourasky Medical Center ( Site 0522), Tel Aviv, , Israel
A O U Policlinico di Modena ( Site 0548), Modena, Abruzzo, Italy
Azienda Ospedaliera Ordine Mauriziano di Torino ( Site 0542), Torino, Piemonte, Italy
Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello ( Site 0547), Palermo, Sicilia, Italy
Istituto Tumori Giovanni Paolo II ( Site 0543), Bari, , Italy
AOU di Bologna Policliico S. Orsola-Malpighi ( Site 0541), Bologna, , Italy
Azienda Ospedaliero Universitaria Careggi ( Site 0549), Firenze, , Italy
Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico ( Site 0550), Milano, , Italy
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0540), Milano, , Italy
Ospedale del Mare ( Site 0545), Napoli, , Italy
Azienda Ospedaliero Universitaria Pisana ( Site 0546), Pisa, , Italy
Ehime University Hospital ( Site 0123), Toon, Ehime, Japan
Kurume University Hospital ( Site 0119), Kurume, Fukuoka, Japan
Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital ( Site 0102), Sapporo, Hokkaido, Japan
Kanazawa University Hospital ( Site 0111), Kanazawa, Ishikawa, Japan
Kagawa University Hospital ( Site 0121), Kita-gun, Kagawa, Japan
Kagawa Prefectural Central Hospital ( Site 0122), Takamatsu, Kagawa, Japan
Toranomon Hospital Kajigaya ( Site 0109), Kawasaki, Kanagawa, Japan
Yokohama City University Medical Center ( Site 0110), Yokohama, Kanagawa, Japan
Kindai University Hospital ( Site 0116), Osakasayama, Osaka, Japan
Saitama Medical University Hospital ( Site 0104), Iruma-gun, Saitama, Japan
Kyorin University Hospital ( Site 0106), Mitaka, Tokyo, Japan
Musashino Red Cross Hospital ( Site 0107), Musashino, Tokyo, Japan
Chiba University Hospital ( Site 0103), Chiba, , Japan
National Hospital Organization Kyushu Medical Center ( Site 0118), Fukuoka, , Japan
Hiroshima University Hospital ( Site 0117), Hiroshima, , Japan
University Hospital, Kyoto Prefectural University of Medicine ( Site 0112), Kyoto, , Japan
Japanese Red Cross Osaka Hospital ( Site 0113), Osaka, , Japan
Osaka Metropolitan University Hospital. ( Site 0114), Osaka, , Japan
Saga-Ken Medical Centre Koseikan ( Site 0120), Saga, , Japan
Toranomon Hospital ( Site 0108), Tokyo, , Japan
The University of Tokyo Hospital ( Site 0105), Tokyo, , Japan
Wakayama Medical University Hospital ( Site 0115), Wakayama, , Japan
National Cancer Center ( Site 0314), Goyang-si, Kyonggi-do, Korea, Republic of
Seoul National University Bundang Hospital ( Site 0313), Seongnam-si, Kyonggi-do, Korea, Republic of
Seoul National University Hospital ( Site 0312), Seoul, , Korea, Republic of
Severance Hospital Yonsei University Health System ( Site 0309), Seoul, , Korea, Republic of
Asan Medical Center ( Site 0310), Seoul, , Korea, Republic of
Samsung Medical Center ( Site 0311), Seoul, , Korea, Republic of
The Catholic University of Korea. Seoul St. Mary s Hospital ( Site 0315), Seoul, , Korea, Republic of
Hospital Universiti Sains Malaysia ( Site 0295), Kubang Kerian, Kelantan, Malaysia
Penang Adventist Hospital ( Site 0289), George Town, Pulau Pinang, Malaysia
Gleneagles Penang ( Site 0290), Penang, Pulau Pinang, Malaysia
Sarawak General Hospital ( Site 0293), Kuching, Sarawak, Malaysia
Institut Kanser Negara - National Cancer Institute ( Site 0294), Putrajaya Wilayah Persekutuan, Wilayah Persekutuan Putrajaya, Malaysia
University Malaya Medical Centre ( Site 0288), Kuala Lumpur, , Malaysia
Christchurch Hospital ( Site 0247), Christchurch, Canterbury, New Zealand
Auckland City Hospital ( Site 0246), Auckland, , New Zealand
Oslo Universitetssykehus HF. Ulleval ( Site 0433), Oslo, , Norway
Izerskie Centrum Pulmonologii i Chemioterapii IZER-MED Spolka z o.o. ( Site 0607), Szklarska Poreba, Dolnoslaskie, Poland
Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie ( Site 0620), Lublin, Lubelskie, Poland
MTZ Clinical Research Sp. z o. o. ( Site 0608), Warsaw, Mazowieckie, Poland
Copernicus PL Sp. z o.o. ( Site 0603), Gdansk, Pomorskie, Poland
ID Clinic ( Site 0619), Myslowice, Slaskie, Poland
SPZOZ MSWIA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie ( Site 0606), Olsztyn, Warminsko-mazurskie, Poland
Szpital Wojewodzki im. Mikolaja Kopernika ( Site 0604), Koszalin, Zachodniopomorskie, Poland
Altay Regional Oncology Dispensary ( Site 0919), Barnaul, Altayskiy Kray, Russian Federation
Siberian Clinical Center of FMBA ( Site 0918), Krasnoyarsk, Krasnoyarskiy Kray, Russian Federation
Krasnoyarsk Regional Clinical Oncological Dispensary ( Site 0648), Krasnoyarsk, Krasnoyarskiy Kray, Russian Federation
Blokhin National Medical Oncology ( Site 0645), Moscow, Moskva, Russian Federation
City Clinical Hospital 1 na. NI. Pirogov ( Site 0662), Moscow, Moskva, Russian Federation
First Moscow State Medical University n.a. I.M.Sechenov ( Site 0661), Moscow, Moskva, Russian Federation
Hadassah Medical-Clinical Research Department ( Site 0920), Moscow, Moskva, Russian Federation
National Medical Research Radiological Centre ( Site 0660), Moscow, Moskva, Russian Federation
Privolzhsky District Medical Center ( Site 0655), Nizhniy Novgorod, Nizhegorodskaya Oblast, Russian Federation
Samara Regional Clinical Oncology Center ( Site 0656), Samara, Samarskaya Oblast, Russian Federation
Road Hospital JSC Russian railways ( Site 0649), Saint Petersburg, Sankt-Peterburg, Russian Federation
Russian Scientific Center of Radiology and Surgical Technologies ( Site 0665), Saint Petersburg, Sankt-Peterburg, Russian Federation
City Clinical Oncology Center ( Site 0646), Saint Petersburg, Sankt-Peterburg, Russian Federation
Tomsk Scientific Research Institute of Oncology ( Site 0657), Tomsk, Tomskaya Oblast, Russian Federation
Hospital Central de Asturias ( Site 0667), Oviedo, Asturias, Spain
Hospital Universitari Parc Tauli ( Site 0681), Sabadell, Barcelona, Spain
Hospital Universitario de Donostia ( Site 0671), San Sebastian, Gipuzkoa, Spain
Complejo Hospitalario Universitario de Santiago ( Site 0668), Santiago de Compostela, La Coruna, Spain
Hospital Universitario Puerta de Hierro ( Site 0678), Majadahonda, Madrid, Spain
Hospital Universitari Vall d Hebron ( Site 0674), Barcelona, , Spain
Hospital General Universitario Gregorio Maranon ( Site 0676), Madrid, , Spain
Hospital Ramon y Cajal ( Site 0673), Madrid, , Spain
Hospital Universitario La Paz ( Site 0677), Madrid, , Spain
Hospital Universitario Virgen del Rocio ( Site 0670), Sevilla, , Spain
Hospital Universitario Miguel Servet-Gastroenterology ( Site 0682), Zaragoza, , Spain
Skane University Hospital ( Site 0692), Malmo, Skane Lan, Sweden
Karolinska Universitetssjukhuset, Huddinge ( Site 0689), Stockholm, Stockholms Lan, Sweden
Norrlands Universitetssjukhus ( Site 0687), Umea, Vasterbottens Lan, Sweden
Sahlgrenska Universitetssjukhuset ( Site 0691), Goteborg, Vastra Gotalands Lan, Sweden
Universitaetsspital Bern ( Site 0710), Bern, Aargau, Switzerland
University Hospital Basel ( Site 0709), Basel, Basel-Stadt, Switzerland
Kantonsspital St. Gallen ( Site 0708), St. Gallen, Sankt Gallen, Switzerland
CHUV (centre hospitalier universitaire vaudois) ( Site 0712), Lausanne, Vaud, Switzerland
Kantonsspital Winterthur ( Site 0714), Winterthur, Zurich, Switzerland
Hopitaux Universitaires de Geneve HUG ( Site 0711), Geneve, , Switzerland
Universitaetsspital Zurich ( Site 0713), Zurich, , Switzerland
Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0335), Kaohsiung, , Taiwan
China Medical University Hospital ( Site 0333), Taichung, , Taiwan
National Cheng Kung University Hospital ( Site 0334), Tainan, , Taiwan
National Taiwan University Hospital ( Site 0330), Taipei, , Taiwan
Taipei Veterans General Hospital ( Site 0331), Taipei, , Taiwan
Chang Gung Medical Foundation. Linkou ( Site 0332), Taoyuan, , Taiwan
Ramathibodi Hospital. ( Site 0352), Bangkok, Krung Thep Maha Nakhon, Thailand
Siriraj Hospital ( Site 0351), Bangkok, Krung Thep Maha Nakhon, Thailand
Maharaj Nakorn Chiangmai Hospital ( Site 0353), Chiang Mai, , Thailand
Srinagarind Hospital ( Site 0354), Khon Kaen, , Thailand
Namik Kemal Universitesi Tip Fakultesi ( Site 0738), Tekirdag, Tekirdas, Turkey
Baskent Unv. Adana Uyg. ve Arast. Hastanesi ( Site 0733), Adana, , Turkey
Gulhane Egitim ve Arastirma Hastanesi ( Site 0741), Ankara, , Turkey
Ankara Sehir Hastanesi ( Site 0731), Ankara, , Turkey
Adnan Menderes University Medical Faculty ( Site 0737), Aydin, , Turkey
Bezmialem Vakif University School of Medicine ( Site 0732), Istanbul, , Turkey
Acıbadem Maslak Hastanesi ( Site 0742), Istanbul, , Turkey
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 0730), Istanbul, , Turkey
Dokuz Eylul Universitesi ( Site 0740), Izmir, , Turkey
Konya Necmettin Erbakan University Medical Faculty ( Site 0736), Konya, , Turkey
Inonu University Faculty of Medicine ( Site 0729), Malatya, , Turkey
VM Medical Park Hastanesi ( Site 0739), Mersin, , Turkey
Regional Clinical Onco Dispensary_ State Medical University ( Site 0782), Chernivtsi, Chernivetska Oblast, Ukraine
Regional Oncology Center of Kharkiv ( Site 0777), Kharkiv, Kharkivska Oblast, Ukraine
National Cancer Institute of the MoH of Ukraine ( Site 0779), Kyiv, Kyivska Oblast, Ukraine
Shalimov s NI of Surgery and Transplantation ( Site 0781), Kyiv, Kyivska Oblast, Ukraine
MI Odessa Regional Oncological Centre ( Site 0776), Odesa, Odeska Oblast, Ukraine
CI City Clinical Hospital # 3 ( Site 0783), Zaporizhzhia, Zaporizka Oblast, Ukraine
Universal Clinic Oberig-Oncology Center ( Site 0786), Kyiv, , Ukraine
Medical Center Dobrobut Clinic ( Site 0785), Kyiv, , Ukraine
Cambridge University Hospitals NHS Trust ( Site 0755), Cambridge, Cambridgeshire, United Kingdom
Weston Park Hospital ( Site 0753), Sheffield, Derbyshire, United Kingdom
The Beatson West of Scotland Cancer Centre ( Site 0750), Glasgow, Glasgow City, United Kingdom
Kings College Hospital NHS Foundation Trust ( Site 0758), London, London, City Of, United Kingdom
Belfast City Hospital ( Site 0752), Belfast, Northern Ireland, United Kingdom
The Clatterbridge Cancer Centre NHS Foundation Trust ( Site 0757), Birkenhead, Wirral, United Kingdom
University Hospital Coventry and Warwickshire NHS Trust ( Site 0754), Coventry, , United Kingdom
Leeds Teaching Hospitals NHS Trust ( Site 0751), Leeds, , United Kingdom
Nottingham University Hospitals NHS Trust ( Site 0756), Nottingham, , United Kingdom
Contact Details
Name: Medical Director
Affiliation: Merck Sharp & Dohme LLC
Role: STUDY_DIRECTOR
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