Spots Global Cancer Trial Database for 4SC-201 (Resminostat) and Sorafenib in Advanced Hepatocellular Carcinoma
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Trial Identification
Brief Title: 4SC-201 (Resminostat) and Sorafenib in Advanced Hepatocellular Carcinoma
Official Title: A Proof-of-concept Phase II Study to Evaluate Efficacy, Safety and Pharmacokinetics of 4SC-201 and the Treatment Combination of Sorafenib Plus 4SC-201 in Patients With Hepatocellular Carcinoma Exhibiting Progressive Disease Under Sorafenib Treatment
Study ID: NCT00943449
Conditions
Study Description
Brief Summary: The purpose of the study is to determine whether 4SC-201 alone or in combination with Sorafenib is effective and safe in the treatment of hepatocellular carcinoma in patients refractory to Sorafenib monotherapy.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
ONKOPLUS Beratung und Hilfe fĂźr Menschen mit Krebs, Berlin, , Germany
Universitätsklinikum Essen (Innere Klinik/Tumorforschung und Zentrum fßr Innere Medizin), Essen, , Germany
Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg (Klinik und Poliklinik fßr Innere Medizin I), Halle, , Germany
Universitätsklinikum Hamburg-Eppendorf (I. Medizinische Klinik und Poliklinik), Hamburg, , Germany
Universitätsklinikum Heidelberg (Medizinische Universitätsklinik/Innere Medizin IV/Nationales Centrum fßr Tumorerkrankungen), Heidelberg, , Germany
Johannes Gutenberg-Universität Mainz (I. Medizinische Klinik und Poliklinik), Mainz, , Germany
Klinikum rechts der Isar der Technischen Universität Mßnchen (Medizinische Klinik und Poliklinik II/Gastroenterologie), Munich, , Germany
Universitätsklinikum Tßbingen (Medizinische Klinik/Innere Medizin I), Tßbingen, , Germany
l'Azienda Ospedaliero-Universitaria di Bologna-Policlinico S. Orsola Malpighi, Bologna, , Italy
l'UniversitĂ degli Studi di Genova (Dipartimento di Medicina Interna e SpecialitĂ Mediche), Genova, , Italy
Istituto Europea di Oncologia EIO, Milano, , Italy
A.O.R.N. Monaldi-Cotugno-CTO, Napoli, , Italy
l'Azienda Ospedaliera di Padova and l'Istituto Oncologico Veneto IOV, Padova, , Italy
l'Ente "Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone", Palermo, , Italy
L'Istituto Clinico Humanitas-Humanitas Mirasole S.p.A., Rozzano-Milano, , Italy
Contact Details
Name: Michael Bitzer, Prof. MD
Affiliation: Medizinische Universitäts-Klinik Tßbingen
Role: PRINCIPAL_INVESTIGATOR
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