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Spots Global Cancer Trial Database for phase ii

Every month we try and update this database with for phase ii cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Phase I/II, Open-label, Multi-center, Two Part Dose-escalation, Safety, Pharmacokinetics (PK) and Efficacy Study of AZD4877 in Patients With Acute Myelogenous Leukemia (AML)NCT00486265
Acute Myelogeno...
AZD4877
18 Years - AstraZeneca
A Study of Famitinib in Patients With Advanced Non-squamous and Non-Small Cell Lung Cancer (NSCLC)NCT02356991
Non-Small Cell ...
Famitinib
Placebo
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
A Study to Evaluate the Efficacy and Safety of Simtuzumab Combined With Gemcitabine for Metastatic Pancreatic AdenocarcinomaNCT01472198
Pancreatic Canc...
Simtuzumab
Gemcitabine
Placebo to matc...
18 Years - Gilead Sciences
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced DiseaseNCT04630743
Dyspnea
Respiratory Ins...
Neoplasms
Pulmonary Disea...
Lung Diseases
Heart Failure
Lung Diseases, ...
Palliative Care
Palliative Medi...
Breathlessness
Cognitive and B...
18 Years - University of Cologne
4SC-201 (Resminostat) in Advanced Colorectal CarcinomaNCT01277406
Advanced Colore...
4SC-201(Resmino...
FOLFIRI
18 Years - 4SC AG
Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD)NCT00862836
Ovarian Cancer
Vandetanib
18 Years - Sanofi
Resminostat (4SC-201) in Relapsed or Refractory Hodgkin's LymphomaNCT01037478
Hodgkin's Lymph...
Resminostat (4S...
18 Years - 4SC AG
Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia in JapanNCT01464411
Leukemia, Myelo...
Myelogenous Leu...
20 Months - Kanto CML Study Group
Phase II Study With Catumaxomab in Patients With Gastric Cancer After Neoadjuvant CTx and Curative ResectionNCT00464893
Gastric Cancer
Gastric Adenoca...
Catumaxomab
catumaxomab
18 Years - Neovii Biotech
Phase II Lung Metcore - Preoperative Metformin for Lung CancerNCT03086733
Non Small Cell ...
Lung Cancer
Metformin
18 Years - 90 YearsUniversity Health Network, Toronto
Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHNNCT02124707
Head and Neck C...
Squamous Cell C...
Cetuximab
Paclitaxel
Carboplatin
18 Years - UNC Lineberger Comprehensive Cancer Center
Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal CancerNCT01853644
Recurrent Epith...
Recurrent Fallo...
Recurrent Prima...
Tivozanib
18 Years - 110 YearsNorthwestern University
Efficacy Study of TLN-4601 in Patients With Recurring Glioblastoma MultiformeNCT00730262
Glioblastoma Mu...
TLN-4601
18 Years - Thallion Pharmaceuticals
A Phase II Study of Spinal RadiosurgeryNCT00573872
Neoplasm
Arteriovenous M...
Radiosurgery
19 Years - University of Alabama at Birmingham
Study to Investigate the Management of Hypertension and Efficacy of AZD2171 in Patients With Advanced Solid TumoursNCT00264004
Tumors
AZD2171
18 Years - AstraZeneca
Bevacizumab and Trabectedin +/- Carboplatin in Advanced Ovarian CancerNCT01735071
Ovarian Epithel...
bevacizumab and...
bevacizumab, tr...
18 Years - Mario Negri Institute for Pharmacological Research
A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard TreatmentsNCT05152472
Unresectable Ga...
Locally Advance...
Metastatic Gast...
Atezolizumab 12...
Imatinib 400 MG
18 Years - Centre Leon Berard
S 81694 Plus Paclitaxel in Metastatic Breast CancerNCT03411161
Metastatic Brea...
Metastatic Trip...
Combination the...
Paclitaxel
Combination the...
18 Years - Servier
Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)NCT03150004
Acute Myeloid L...
Myelodysplastic...
Cladribine, Cyt...
Cladribine and ...
18 Years - Medical College of Wisconsin
Alternate Day Dosing of Pomalidomide in Patients With Refractory Multiple MyelomaNCT03520985
Refractory Mult...
Pomalidomide
Dexamethasone
18 Years - Swiss Group for Clinical Cancer Research
Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular CarcinomaNCT00250796
Liver
Cancer
Thalidomide, al...
Thalidomide, in...
18 Years - University of New Mexico
Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected MelanomaNCT00199901
Melanoma
NY-ESO-1 ISCOMA...
ISCOMATRIX® adj...
18 Years - Ludwig Institute for Cancer Research
Study of Modified FOLFIRINOX in Advanced Pancreatic CancerNCT01523457
Metastatic Panc...
Pancreatic Canc...
Folfirinox
18 Years - Yale University
FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic CancerNCT01688336
Pancreatic Canc...
FOLFIRINOX
18 Years - UNC Lineberger Comprehensive Cancer Center
Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)NCT00250068
Lung Diseases
Cancer
Liposomal 9-Nit...
18 Years - University of New Mexico
Paclitaxel and Capecitabine in Patients With Metastatic/Recurrence Esophageal CancerNCT00453323
Esophageal Canc...
Paclitaxel
Capecitabine
18 Years - National Cancer Center, Korea
Pazopanib In Patients With Relapsed Or Refractory Soft Tissue SarcomaNCT00297258
Sarcoma, Soft T...
pazopanib
21 Years - GlaxoSmithKline
Platinum Resistant Ovarian Cancer Evaluation of Doxil and Vintafolide (MK-8109, EC145) Combination Therapy (8109-009, EC-FV-04)NCT00722592
Ovarian Cancer
Vintafolide
pegylated lipos...
EC20
18 Years - Endocyte
A Phase II Study of Spinal RadiosurgeryNCT00573872
Neoplasm
Arteriovenous M...
Radiosurgery
19 Years - University of Alabama at Birmingham
A Phase II Study of MGCD0103 (MG-0103) in Patients With Refractory Chronic Lymphocytic LeukemiaNCT00431873
Lymphocytic Leu...
MGCD0103
18 Years - Mirati Therapeutics Inc.
Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver MetastasesNCT01508000
Colorectal Canc...
Liver Metastase...
KRAS Wild Type ...
FOLFOX6
Bevacizumab
Panitumumab
Surgery
18 Years - 75 YearsEuropean Organisation for Research and Treatment of Cancer - EORTC
Combination Chemotherapy (FLAC) Combined With Granulocyte-Macrophage Colony Stimulating Factor in Locally Advanced and Metastatic Breast CancerNCT00001239
Breast Cancer
Breast Neoplasm...
FLAC with GM-CS...
- National Institutes of Health Clinical Center (CC)
A Phase II Study of Spinal RadiosurgeryNCT00573872
Neoplasm
Arteriovenous M...
Radiosurgery
19 Years - University of Alabama at Birmingham
Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLCNCT04765709
Non-small Cell ...
durvalumab plus...
Durvalumab plus...
durvalumab
18 Years - Mario Negri Institute for Pharmacological Research
Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion DependenceNCT04797000
Myelodysplastic...
Eltrombopag
Placebo
20 Years - 99 YearsNovartis
A Study of Apatinib in Patients With Advanced Non-squamous and Non-small Cell Lung CancerNCT01270386
Non-Small-Cell ...
apatinib
placebo
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
Study Of Sunitinib In Patients With Recurrent Paraganglioma/PheochromocytomaNCT00843037
Paraganglioma
Pheochromocytom...
Sunitinib
18 Years - University Health Network, Toronto
Biweekly Avastin and Docetaxel as the First Line Treatment for Patients With Metastatic Breast CancerNCT00979641
Neoplasms
Docetaxel
18 Years - Tampere University Hospital
A Trial of Strontium +/- Cisplatin for the Palliation of Bone Pain Secondary to Hormone Refractory Prostate CancerNCT00156884
Hormone Refract...
Bone Metastases
strontium-89
cisplatin
18 Years - AHS Cancer Control Alberta
Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain MetastasesNCT04001725
Brain Metastase...
Melanoma
Lung Cancer
Breast Cancer
Dexamethasone
Metformin
18 Years - 75 YearsFondazione IRCCS Istituto Nazionale dei Tumori, Milano
Study of Modified FOLFIRINOX in Advanced Pancreatic CancerNCT01523457
Metastatic Panc...
Pancreatic Canc...
Folfirinox
18 Years - Yale University
Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected MelanomaNCT00199901
Melanoma
NY-ESO-1 ISCOMA...
ISCOMATRIX® adj...
18 Years - Ludwig Institute for Cancer Research
Phase II Trial of Abraxane and Capecitabine in Metastatic Colon Cancer (COL 01)NCT00625573
Colorectal Canc...
Abraxane
18 Years - 90 YearsMt. Sinai Medical Center, Miami
Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid LeukemiaNCT00660036
Acute Myeloid L...
Gemtuzumab ozog...
Mitoxantrone
Etoposide
18 Years - 70 YearsUniversity of Pittsburgh
Nintedanib as Switch Maintenance Treatment of Pleural Malignant MesotheliomaNCT02863055
Malignant Pleur...
Nintedanib
Placebo
18 Years - 90 YearsEuropean Organisation for Research and Treatment of Cancer - EORTC
Trial of PI-88 With Dacarbazine in Patients With Metastatic MelanomaNCT00130442
Melanoma
PI-88 and dacar...
dacarbazine or ...
18 Years - Cellxpert Biotechnology Corp.
Paclitaxel in Patients With Metastatic or Advanced Gastrointestinal Stromal Tumors (GIST) After Failure to Imatinib and SunitinibNCT02607332
Gastrointestina...
Paclitaxel
20 Years - Asan Medical Center
A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against DoxorubicinNCT00268853
Diffuse Large-C...
CPOP-R
CHOP-R
18 Years - CTI BioPharma
Oxaliplatin and Docetaxel for Recurrent or Metastatic Head and Neck CancerNCT00557206
Neoplasms
Head and Neck N...
Oxaliplatin and...
18 Years - Minneapolis Veterans Affairs Medical Center
Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular CarcinomaNCT00250796
Liver
Cancer
Thalidomide, al...
Thalidomide, in...
18 Years - University of New Mexico
Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)NCT03150004
Acute Myeloid L...
Myelodysplastic...
Cladribine, Cyt...
Cladribine and ...
18 Years - Medical College of Wisconsin
1st Line Durvalumab in PS 2 NSCLC PatientsNCT03620669
NSCLC Stage IV
NSCLC Stage III...
Durvalumab
18 Years - Swiss Group for Clinical Cancer Research
Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction AdenocarcinomaNCT00813072
Stomach Neoplas...
Esophageal Neop...
PEP02
irinotecan
docetaxel
18 Years - PharmaEngine
Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative DiseasesNCT00910728
Primary Myelofi...
Post-Polycythae...
Essential Throm...
AZD1480
25 Years - 99 YearsAstraZeneca
E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatocellular CarcinomaNCT01271504
Hepatocellular ...
Sorafenib
Sorafenib
18 Years - Eisai Inc.
Study of OGX-011 Given Prior to Radical Prostatectomy in Patients With Localized Prostate CancerNCT00138918
Prostate Cancer
OGX-011
18 Years - University of British Columbia
Study of a Tiotropium Inhaler For Shortness of Breath in Advanced Non-Small Cell Lung CancerNCT01172925
NSCLC
Dyspnea
Tiotropium
Placebo
18 Years - McMaster University
Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX)NCT00278889
Colorectal Canc...
AZD2171
5-fluorouracil
Leucovorin
Oxaliplatin
Bevacizumab
18 Years - AstraZeneca
Niraparib Efficacy in Patient With Unresectable MesotheliomaNCT05455424
Mesothelioma, M...
Niraparib Oral ...
Active Symptom ...
18 Years - University Hospital Southampton NHS Foundation Trust
A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).NCT03946670
Myelodysplastic...
MBG453
Placebo
Hypomethylating...
18 Years - Novartis
Neoadjuvant Pazopanib in Renal Cell CarcinomaNCT01361113
Renal Cell Carc...
Pazopanib
18 Years - UNC Lineberger Comprehensive Cancer Center
Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and NeckNCT01412229
Head and Neck C...
Cetuximab
Nab-paclitaxel
Carboplatin
18 Years - UNC Lineberger Comprehensive Cancer Center
Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic CarcinomaNCT00744640
Locally Advance...
Metastatic Panc...
gemcitabine, ox...
18 Years - University Hospital, Basel, Switzerland
Phase II Trial of HM61713 for the Treatment of ≥2nd Line T790M Mutation Positive Adenocarcinoma of the LungNCT02485652
Non Small Cell ...
HM61713
20 Years - Hanmi Pharmaceutical Company Limited
Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib.NCT03944304
Gastrointestina...
Paclitaxel
20 Years - Asan Medical Center
Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)NCT03150004
Acute Myeloid L...
Myelodysplastic...
Cladribine, Cyt...
Cladribine and ...
18 Years - Medical College of Wisconsin
EUCROSS: European Trial on Crizotinib in ROS1 Translocated Lung CancerNCT02183870
Lung Cancer
Adenocarcinoma
NSCLC
Crizotinib
18 Years - University of Cologne
A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer PatientsNCT03145961
Triple Negative...
Pembrolizumab
16 Years - Institute of Cancer Research, United Kingdom
Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal CancerNCT01853644
Recurrent Epith...
Recurrent Fallo...
Recurrent Prima...
Tivozanib
18 Years - 110 YearsNorthwestern University
Capecitabine and Cisplatin (XP)+Sorafenib in Advanced Gastric Cancer (AGC): Sorafenib+XPNCT00565370
Advanced Gastri...
Capecitabine, C...
18 Years - 75 YearsAsan Medical Center
Platinum Resistant Ovarian Cancer Evaluation of Doxil and Vintafolide (MK-8109, EC145) Combination Therapy (8109-009, EC-FV-04)NCT00722592
Ovarian Cancer
Vintafolide
pegylated lipos...
EC20
18 Years - Endocyte
A Study of Famitinib in Patients With Advanced Colorectal CancerNCT01762293
Colorectal Canc...
Colorectal Canc...
Colorectal Canc...
Famitinib
placebo
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
Phase II Trial of Carboplatin +/- Tocilizumab for Metastatic Triple Negative and ER-low Breast CancersNCT05846789
Metastatic Brea...
Triple Negative...
Estrogen-recept...
Carboplatin
Tocilizumab
18 Years - Indiana University
1st Line Durvalumab in PS 2 NSCLC PatientsNCT03620669
NSCLC Stage IV
NSCLC Stage III...
Durvalumab
18 Years - Swiss Group for Clinical Cancer Research
STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDSNCT04878432
Myelodysplastic...
MBG453
Azacitidine
Decitabine
INQOVI (oral de...
18 Years - 99 YearsNovartis
Phase II Trial of Carboplatin +/- Tocilizumab for Metastatic Triple Negative and ER-low Breast CancersNCT05846789
Metastatic Brea...
Triple Negative...
Estrogen-recept...
Carboplatin
Tocilizumab
18 Years - Indiana University
131-I-TM-601 Study in Adults With Recurrent High-Grade GliomaNCT00114309
Malignant Gliom...
Glioblastoma Mu...
GBM
Anaplastic Astr...
Oligo-Astrocyto...
Gliosarcoma
131-I-TM-601
131I-TM601
18 Years - TransMolecular
Neoadjuvant Pazopanib in Renal Cell CarcinomaNCT01361113
Renal Cell Carc...
Pazopanib
18 Years - UNC Lineberger Comprehensive Cancer Center
MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory DiseaseNCT00374296
Myelogenous Leu...
Myelodysplastic...
MGCD0103
18 Years - Mirati Therapeutics Inc.
Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)NCT01829503
Acute Myeloid L...
decitabine and ...
Supportive Care
60 Years - University of Pittsburgh
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