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Brief Title: Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors
Official Title: A Phase 1, First-In-Human, Multicenter, Open-Label, Study of GQ1001, a HER2 Targeted Antibody-Drug Conjugate, Administered Intravenously, in Adult Patients With HER2-Positive Advanced Solid Tumors
Study ID: NCT04450732
Brief Summary: Phase I Dose Finding Study for GQ1001 in Patients with HER2-Positive Advanced Solid Tumors
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
M.D. Anderson Cancer Center, Houston, Texas, United States
Scientia Clinical Research Limited, Randwick, New South Wales, Australia
Cabrini Institute in Melbourne, Australia, Melbourne, Victoria, Australia
The first affiliated hospital of Bengbu medical college, Bengbu, Anhui, China
Beijing Tongren Hospital Affiliated to Capital University of Medical Sciences, Beijing, Beijing, China
Chinese PLA general hospital, Beijing, Beijing, China
Southern Medical University Hospital in the south, Guangzhou, Guangdong, China
Sun Yat-sen Memorial Hospital, Guangzhou, Guangdong, China
Henan Cancer Hospital, Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Hubei Huazhong University of Science and provincial Cancer Hospital Affiliated Union Hospital of Tongji Medical College, Wuhan, Hubei, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China
Shandong Tumor Hospital, Jinan, Shandong, China
Shanghai Ninth People's Hospital affiliated with the Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Zhongshan Hospital, Shanghai, Shanghai, China
Ruijin Hospital, Affiliated to Shanghai Jiaotong University, Shanghai, Shanghai, China
Shanghai East Hospital, Shanghai, Shanghai, China
Changhai Hospital of Shanghai, Shanghai, Shanghai, China
Shanghai Pulmonary Hospital, Shanghai, Shanghai, China
West China School of Medicine and West China Hospital, Sichuan University, Chengdu, Sichuan, China
First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China