Neoplasms

All Conditions

Skin and Connective Tissue Diseases

Respiratory Tract (Lung and Bronchial) Diseases

Digestive System Diseases

Rare Diseases

Carcinoma

Breast Neoplasms

Carcinoma, Non-Small-Cell Lung

Lung Neoplasms

Biliary Tract Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Biliary Tract Diseases

Gastrointestinal Diseases

Biliary Tract Cancer

All Drugs and Chemicals

Antibodies

Immunoglobulins

GQ1001 will be administered intravenously every 21 days. Dose Escalation will be guided by a modified 3+3 design.

GQ1001 at the Dose Recommended for Dose Expansion will be administered intravenously every 21 days. Dose expansion will further evaluate the MTD or DRDE in different types of malignant solid tumor in four cohorts.

GQ1001

Yan Shi

Charlotte Lemech, MD

Huan Zhou

Dianming Li

Shurong Zhang

Bo Yang

Yabing Guo

Jieqiong Liu

Yanqiu Zhao

Hong Zong

Kunyu Yang

Dongde Wu

Shanzhi Gu

Zhendong Li

Zhehai Wang

Yuping Sun

Wei Guo

Jia Fan

Huichuan Sun

Jun Zhang

Jin Li

Ye Guo

Xianbao Zhan

Caicun Zhou

Lei Liu

Lulu Liu

Meiyu Fang

Phase I Dose Finding Study for GQ1001 in Patients with HER2-Positive Advanced Solid Tumors

Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors

A Phase 1, First-In-Human, Multicenter, Open-Label, Study of GQ1001, a HER2 Targeted Antibody-Drug Conjugate, Administered Intravenously, in Adult Patients With HER2-Positive Advanced Solid Tumors

Adverse events will be assessed using NCI CTCAE version 5.0 and will be evaluated by the investigator and the sponsor for the eligibility of DLT.

The SRC will also determine the MTD/DRDE based on the totality of data for all tested dose levels.

Anti-GQ1001 antibody/anti-therapeutic antibody

GeneQuantum Healthcare (Suzhou) Co., Ltd.

Spots Global Cancer Trial Database for gq1001

Every month we try and update this database with for gq1001 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for gq1001

Every month we try and update this database with for gq1001 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for gq1001 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.