Spots Global Cancer Trial Database for Neoadjuvant Study of Pyrotinib in Combination With Trastuzumab in Patients With HER2 Positive Breast Cancer
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Trial Identification
Brief Title: Neoadjuvant Study of Pyrotinib in Combination With Trastuzumab in Patients With HER2 Positive Breast Cancer
Official Title: A Randomized, Muticenter Double-blind Phase III Study of Neoadjuvant Pyrotinib Plus Trastuzumab and Docetaxel Compared With Placebo Plus Trastuzumab and Docetaxel in Women With HER2 Positive Early Stage or Locally Advanced Breast Cancer
Study ID: NCT03588091
Conditions
Study Description
Brief Summary: This is a randomised, double-blind multicenter Phase III study for evaluating the efficacy and safety of neoadjuvant pyrotinib and trastuzumab plus docetaxel versus placebo and trastuzumab plus docetaxel given as neoadjuvant treatment in HER2 positive early stage or locally advanced breast cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Peking University People's Hospital, Beijing, Beijing, China
The Fifth Medical Center of Chinese PLA General Hospital, Beijing, Beijing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
Sun Yet-Sen University Cancer Center, Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
The affiliated cancer hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China
Huai'an First People's Hospital, Huaian, Jiangsu, China
JiangSu Province Hospital, Nanjing, Jiangsu, China
Shandong Cancer Hospital, Jinan, Shandong, China
The Affiliated Hospital Of Qingdao University, Qingdao, Shandong, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
The Second Affiliated Hospital Of Xi'an Jiaotong University, Xian, Shanxi, China
The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Contact Details
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