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Spots Global Cancer Trial Database for pyrotinib

Every month we try and update this database with for pyrotinib cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Pyrotinib in Combination With Neoadjuvant Chemotherapy in HR+/HER2-, HER4 High Expression Breast Cancer Patients: A Phase II TrialNCT04872985
Breast Cancer
Hormone-recepto...
Pyrotinib
Epirubicin
Doxorubicin Hyd...
Cyclophosphamid...
Docetaxel
Nab paclitaxel
Placebo
18 Years - 75 YearsSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Real World Study of Pyrotinib in Human Epidermal Growth Factor Receptor-2 (HER2) Positive Breast CancerNCT04158505
HER2-positive B...
non-interventio...
18 Years - ChineseAMS
Pyrotinib Plus Vinorelbine in HER2+ Metastatic Breast Cancer PatientsNCT04517305
Breast Cancer
18 Years - Fudan University
Inetetamab in Combination With Pyrotinib in HER2 Mutant or Amplified Advanced Non-small Cell Lung CancerNCT05016544
Non-small Cell ...
inetetamab
Pytotinib
18 Years - Sun Yat-sen University
Pyrotinib Combined With Capecitabine in HER-2 Positive Advanced Breast Cancer and Brain Metastases (Post-PERMEATE)NCT05359120
Breast Cancer
- Henan Cancer Hospital
A Prospective, Open, Multicenter Single-arm Clinical Studie of Docetaxel, Carboplatin Combined With Inetetamab and Pyrotinib in the Treatment of Local-advanced HER2-positive Breast CancerNCT06234137
Breast Neoplasm...
Docetaxel
Carboplatin
Inetetamab
Pyrotinib
18 Years - 75 YearsFirst Affiliated Hospital of Wenzhou Medical University
A Study of Pyrotinib Plus Vinorelbine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast CancerNCT03997539
Metastatic Brea...
Pyrotinib
Treatment of ph...
vinorelbine
18 Years - 70 YearsSun Yat-sen University
Treatment With Pyrotinib-Based Therapy in Lapatinib Resistant HER2-Positive Metastatic Breast CancerNCT04899128
Breast Cancer
Pyrotinib
18 Years - 70 YearsThe First Affiliated Hospital with Nanjing Medical University
Disitamab Vedotin + Pyrotinib Versus THP in the First-line Treatment for HER2+ Advanced Breast Cancer Clinical TrialNCT06278870
HER2-positive M...
First-line Trea...
disitamab vedot...
Pyrotinib
trastuzumab
Pertuzumab
taxane drug
18 Years - 75 YearsSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
A Study of Pyrotinib Plus Capecitabine in Patients With HER2+ Metastatic Breast CancerNCT02973737
HER2 Positive M...
pyrotinib
placebo
Capecitabine
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
Pyrotinib Plus Vinorelbine Versus Lapatinib Plus CapecitabineNCT04850625
Breast Cancer
18 Years - Fudan University
The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC).NCT06217185
HER2-positive B...
Advanced Breast...
Pyrotinib
Trastuzumab
Taxanes
Capecitabine
18 Years - 70 YearsHebei Medical University Fourth Hospital
Study of Pyrotinib in Patients With Human Epidermalgrowth Factor Receptor 2 (HER2) Positive Advanced Breast CancerNCT01937689
Breast Cancer
Pyrotinib
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
Pyrotinib Plus Vinorelbine Versus Lapatinib Plus CapecitabineNCT04850625
Breast Cancer
18 Years - Fudan University
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer(MAPS)NCT05087706
Salivary Gland ...
Pyrotinib
Bicalutamide
Leuprorelin
18 Years - Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Study to Evaluate SHR6390 Combined With Pyrotinib in Patients With HER2 Positive Gastric CancerNCT03480256
Gastric Cancer
SHR6390
18 Years - 75 YearsPeking University
Molecularly Targeted Umbrella Study in Luminal Advanced Breast CancerNCT04355858
Breast Cancer
Metastatic Canc...
SHR7390
Famitinib
SHR3162
Pyrotinib
Capecitabine
SHR1210
Everolimus
Nab paclitaxel
SHR2554
SHR3680
SHR6390
SHR1701
SERD
AI
VEGFi
18 Years - 75 YearsFudan University
Continuous or Intermittent Extension of Adjuvant Pyrotinib for Invasive HER2-positive Breast CancerNCT05910398
Breast Cancer I...
pyrotinib
18 Years - 70 YearsRenJi Hospital
Inetetamab Combined With Pyrotinib and Chemotherapy in the Treatment of HER2 Positive Metastatic Breast CancerNCT04681911
Breast Cancer
Inetetamab
Pyrotinib
Capecitabine
Gemcitabine
Vinorelbine
Carboplatin
Albumin paclita...
Eribulin
18 Years - 70 YearsSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Neoadjuvant Study of Pyrotinib in Combination With Trastuzumab in Patients With HER2 Positive Breast CancerNCT03588091
HER2-positive B...
Pyrotinib
Placebo Oral Ta...
Trastuzumab
Docetaxel
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
Phase II Clinical Study of Pyrotinib in First-line Treatment of Primary HER2-amplified/Mutated Advanced Non-small Cell Lung CancerNCT05751018
Non-small Cell ...
Pyrotinib
18 Years - Peking Union Medical College Hospital
Single-arm, Multi-center Clinical Study of Pyrotinib Maleate Tablets Combined With Albumin-bound Paclitaxel and Trastuzumab in Neoadjuvant Treatment of Her2-positive Early or Locally Advanced Breast CancerNCT04917900
Breast Cancer
Pyrotinib combi...
18 Years - 70 YearsWest China Hospital
Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast CancerNCT05076695
Estrogen Recept...
HER2-positive B...
Palbociclib
trastuzumab
pyrotinib
fulvestrant
18 Years - Fudan University
A Clinica Study of Pyrotinib in Patients of Advanced Non-Small Cell Lung Cancer With HER2 MutationNCT02834936
Non Small Cell ...
pyrotinib
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
Pyrotinib After Trastuzumab-based Adjuvant Therapy in Patients With HER2-positive Breast CancerNCT05880927
Breast Cancer
Pyrotinib
18 Years - 75 YearsTaizhou Hospital
A Study of Pyrotinib Plus Vinorelbine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast CancerNCT03997539
Metastatic Brea...
Pyrotinib
Treatment of ph...
vinorelbine
18 Years - 70 YearsSun Yat-sen University
Pyrotinib Plus Vinorelbine in Participants With HER2-positive Previously Treated Locally Advanced or Metastatic Breast CancerNCT04605575
Breast Cancer
Pyrotinib
Breast Diseases
Vinorelbine
HER2-positive B...
Pyrotinib 320mg...
Pyrotinib 400mg...
Pyrotinib plus ...
18 Years - 70 YearsSun Yat-sen University
Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM PathwayNCT04736589
Breast Cancer
Inetetamab
Rapamycin
Pyrotinib
Chemotherapy
18 Years - 85 YearsPeking Union Medical College
Real-world Study of Pyrotinib in Neoadjuvant Therapy for HER2-positive Breast CancerNCT05561686
HER2-positive B...
Pyrotinib
18 Years - 65 YearsHunan Cancer Hospital
Phase 2 Study of Pyrotinib in Previously Treated Patients With NSCLC Having EGFR or ERBB2 Exon 20 Insertion MutationNCT04063462
Non Small Cell ...
Pyrotinib
18 Years - 80 YearsTianjin Medical University Cancer Institute and Hospital
Pyrotinib as Neoadjuvant Agent for Non-objective Response HER2-positive Early Breast CancerNCT04717531
Breast Cancer
Pyrotinib
Trastuzumab
Pertuzumab
Docetaxel
Epirubicin
Cyclophosphamid...
18 Years - 70 YearsThe First Affiliated Hospital with Nanjing Medical University
A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 MutationNCT05745740
Non-small Cell ...
RC48-ADC
Pyrotinib
18 Years - 80 YearsRemeGen Co., Ltd.
Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain MetastasesNCT05769010
Metastatic Brea...
SHR-A1811
Pyrotinib
Bevacizumab
18 Years - 75 YearsHenan Cancer Hospital
Pyrotinib Plus Trastuzumab Versus Pertuzumab Plus TrastuzumabNCT05572645
Breast Cancer
Pyrotinib Plus ...
Pertuzumab Plus...
18 Years - Fudan University
Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant TherapyNCT05582499
Breast Neoplasm
Breast Cancer
Breast Tumors
Triple-Negative...
HER2-positive B...
HER2-negative B...
Hormone Recepto...
Hormone Recepto...
Early-stage Bre...
Locally Advance...
Dalpiciclib
Pyrotinib
SHR-A1811
SHR-1316
Camrelizumab
Trophoblast cel...
Pertuzumab
Trastuzumab
Goserelin
Letrozole
Nab paclitaxel
Carboplatin
Epirubicin
Cyclophosphamid...
Fluzoparib
HER2 ADC
18 Years - 70 YearsFudan University
Pyrotinib Combined With Trastuzumab, Dalpiciclib, Letrozole Versus TCbHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HR +/HER2 + Breast CancerNCT05638594
Breast Cancer
Pyrotinib
Trastuzumab
Dalpiciclib
Letrozole
Pertuzumab
Docetaxel
Carboplatin
Gonadotropin-re...
18 Years - 75 YearsShengjing Hospital
Pyrotinib in Combination With Trastuzumab in Treatment-refractory, HER2-positive Metastatic Colorectal Cancar.NCT03843749
Colorectal Canc...
Pyrotinib
18 Years - 75 YearsShanghai Changzheng Hospital
Molecularly Targeted Umbrella Study in Luminal Advanced Breast CancerNCT04355858
Breast Cancer
Metastatic Canc...
SHR7390
Famitinib
SHR3162
Pyrotinib
Capecitabine
SHR1210
Everolimus
Nab paclitaxel
SHR2554
SHR3680
SHR6390
SHR1701
SERD
AI
VEGFi
18 Years - 75 YearsFudan University
The Basket Study of Pyrotinib Maleate for HER2-Postive Solid TumorNCT04179656
Solid Tumor
HER2 Gene Mutat...
HER-2 Gene Ampl...
HER-2 Protein O...
Pyrotinib
18 Years - 75 YearsTianjin Medical University Second Hospital
Pyrotinib Combined With Capecitabine and Bevacizumab for Patients With HER2 Positive Breast Cancer and Brain MetastasesNCT06152822
Breast Cancer W...
pyrotinib+capec...
18 Years - Tongji Hospital
Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) AdenocarcinomaNCT05111444
Gastric Neoplas...
Gastroesophagea...
Camrelizumab
Pyrotinib
Capecitabine
Oxaliplatin
Paclitaxel
S-1
18 Years - 75 YearsFudan University
A Study of Evaluating The Effects Of Pyrotinib After Adjuvant Trastuzumab In Women With Early Stage Breast CancerNCT03980054
Breast Cancer
Pyrotinib
Placebo
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 MutationNCT05745740
Non-small Cell ...
RC48-ADC
Pyrotinib
18 Years - 80 YearsRemeGen Co., Ltd.
Molecularly Targeted Umbrella Study in Luminal Advanced Breast CancerNCT04355858
Breast Cancer
Metastatic Canc...
SHR7390
Famitinib
SHR3162
Pyrotinib
Capecitabine
SHR1210
Everolimus
Nab paclitaxel
SHR2554
SHR3680
SHR6390
SHR1701
SERD
AI
VEGFi
18 Years - 75 YearsFudan University
Trastuzumab Combined With Pertuzumab for Adjuvant Treatment of Breast Cancer After Neoadjuvant TherapyNCT04973319
Breast Cancer
Pyrotinib
Trastuzumab
18 Years - 75 YearsShengjing Hospital
Pyrotinib Plus Thalidomide in Advanced NSCLC Patients Harboring HER2 Exon 20 InsertionsNCT04382300
Non-small-cell ...
pyrotinib combi...
18 Years - 80 YearsShanghai Chest Hospital
Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast CancerNCT04066790
Breast Cancer
Pyrotinib
nab-Paclitaxel
Trastuzumab
EC chemotherapy
Surgery
18 Years - 75 YearsShanghai Jiao Tong University School of Medicine
Dalpiciclib Plus Fulvestrant With Pyrotinib in Hormone Receptor-positive, HER2-low Advanced Breast Cancer That Progressed on Previous CDK4/6i Plus AI TherapyNCT05806671
Breast Cancer
Dalpiciclib
Pyrotinib
Fulvestrant
18 Years - Tianjin Medical University Cancer Institute and Hospital
Efficacy and Safety of Pyrotinib Maleate Combined With ARX788 Neoadjuvant Treatment in Breast Cancer PatientsNCT04983121
Breast Neoplasm...
Next-generation...
18 Years - 75 YearsShengjing Hospital
Inetetamab in Combination With Pyrotinib in HER2 Mutant or Amplified Advanced Non-small Cell Lung CancerNCT05016544
Non-small Cell ...
inetetamab
Pytotinib
18 Years - Sun Yat-sen University
Study of Pyrotinib in Patients With Human Epidermalgrowth Factor Receptor 2 (HER2) Positive Advanced Breast CancerNCT01937689
Breast Cancer
Pyrotinib
18 Years - 70 YearsJiangsu HengRui Medicine Co., Ltd.
Pyrotinib Combined With Trastuzumab Plus Aromatase Inhibitor in Treatment of Breast CancerNCT04088110
Breast Cancer F...
HER2-positive B...
Hormone Recepto...
Metastatic Brea...
Breast Diseases
Hormone Recepto...
Pyrotinib
Trastuzumab
Aromatase Inhib...
18 Years - 70 YearsFuzhou General Hospital
Efficacy and Safety of Pyrotinib in Patients With HER2 Mutation Advanced Non-Small Cell Lung CancerNCT02535507
Non-small Cell ...
Pyrotinib
18 Years - 80 YearsTongji University
Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) AdenocarcinomaNCT05111444
Gastric Neoplas...
Gastroesophagea...
Camrelizumab
Pyrotinib
Capecitabine
Oxaliplatin
Paclitaxel
S-1
18 Years - 75 YearsFudan University
RC48 Combined With EGFR or HER2 TKI for Locally Advanced or Metastatic NSCLC Patients With HER2 AlterationsNCT06185400
Non Small Cell ...
ERBB2 Mutation-...
ERBB2 Gene Dupl...
Disitamab Vedot...
Disitamab Vedot...
third-generatio...
pyrotinib
18 Years - Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast CancerNCT05076695
Estrogen Recept...
HER2-positive B...
Palbociclib
trastuzumab
pyrotinib
fulvestrant
18 Years - Fudan University
Pyrotinib Plus Trastuzumab and Chemotherapy in HER2+ Metastatic Breast Cancer PatientsNCT05839288
Breast Cancer
18 Years - Fudan University
Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast CancerNCT04126525
Breast Cancer F...
Pyrotinib
18 Years - 70 YearsRenJi Hospital
A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast CancerNCT04095390
Metastatic Brea...
HER2-positive B...
Pyrotinib
SHR6390
Letrozole
Capecitabine
18 Years - 70 YearsShandong Cancer Hospital and Institute
A Study of Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+Metastatic Breast Cancer Who Have Prior Received Anthracyclin, Taxane or TrastuzumabNCT02422199
HER2 Positive M...
pyrotinib
Lapatinib
capecitabine
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
Pharmacokinetic Study of Pyrotinib and Docetaxel in Combination With Trastuzumab in Patients With HER2 Metastatic Breast CancerNCT04367090
Metastatic Brea...
Docetaxel, tras...
Pyrotinib
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast CancerNCT04126525
Breast Cancer F...
Pyrotinib
18 Years - 70 YearsRenJi Hospital
Pyrotinib in Breast Cancer Patients With Poor Response to the Neoadjuvant Treatment of Trastuzumab and PertuzumabNCT04255056
Breast Cancer
Pyrotinib
18 Years - 75 YearsSun Yat-sen University
Inetetamab Combined With Pyrotinib Plus Oral Vinorelbine for the Treatment of HER2-positive Metastatic Breast CancerNCT05823623
Breast Cancer
Inetetamab
Pyrotinib
Oral Vinorelbin...
18 Years - 85 YearsThe First Affiliated Hospital with Nanjing Medical University
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer(MAPS)NCT05087706
Salivary Gland ...
Pyrotinib
Bicalutamide
Leuprorelin
18 Years - Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Phase I Study of Pyrotinib in Patients With HER2-positive Solid TumorsNCT02500199
Breast Cancer
Gastric Cancer
Solid Tumors
NSCLC
Pyrotinib
18 Years - Hengrui Therapeutics, Inc.
Pyrotinib Versus Pertuzumab in Combination With Neoadjuvant Trastuzumab and Nab-Paclitaxel in HER2+ Early or Locally Advanced Breast CancerNCT04900311
HER2+ Early or ...
pyrotinib + tra...
pertuzumab + tr...
18 Years - 75 YearsTianjin Medical University Cancer Institute and Hospital
Pyrotinib in Metastatic HER2 Non-amplified But HER2 Mutant Breast CancerNCT03412383
Breast Cancer
HER2 Gene Mutat...
Pyrotinib
18 Years - 70 YearsPeking Union Medical College
A Clinica Study of Pyrotinib in Patients of Advanced Non-Small Cell Lung Cancer With HER2 MutationNCT02834936
Non Small Cell ...
pyrotinib
18 Years - 75 YearsJiangsu HengRui Medicine Co., Ltd.
A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast CancerNCT04095390
Metastatic Brea...
HER2-positive B...
Pyrotinib
SHR6390
Letrozole
Capecitabine
18 Years - 70 YearsShandong Cancer Hospital and Institute
Pyrotinib Versus Pertuzumab in Combination With Neoadjuvant Trastuzumab and Nab-Paclitaxel in HER2+ Early or Locally Advanced Breast CancerNCT04900311
HER2+ Early or ...
pyrotinib + tra...
pertuzumab + tr...
18 Years - 75 YearsTianjin Medical University Cancer Institute and Hospital
A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer PatientsNCT05426486
HER2-positive B...
ARX788
Pyrotinib malea...
Trastuzumab
Pertuzumab
Docetaxel
Carboplatin
18 Years - 75 YearsShengjing Hospital
Adjuvant Dual Anti-HER2 Therapy in Patients With Small, Node-negative, HER2-positive Breast CancerNCT04158856
HER2-positive B...
Pyrotinib
Trastuzumab
18 Years - 70 YearsSecond Affiliated Hospital, School of Medicine, Zhejiang University
A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer PatientsNCT05426486
HER2-positive B...
ARX788
Pyrotinib malea...
Trastuzumab
Pertuzumab
Docetaxel
Carboplatin
18 Years - 75 YearsShengjing Hospital
Pyrotinib Plus Vinorelbine in Participants With HER2-positive Previously Treated Locally Advanced or Metastatic Breast CancerNCT04605575
Breast Cancer
Pyrotinib
Breast Diseases
Vinorelbine
HER2-positive B...
Pyrotinib 320mg...
Pyrotinib 400mg...
Pyrotinib plus ...
18 Years - 70 YearsSun Yat-sen University
Pyrotinib Plus Trastuzumab After First-line TH (P) Treatment With HER-2 Positive Breast CancerNCT05255523
Advanced Breast...
pyrotinib
18 Years - 75 YearsFujian Medical University Union Hospital
Efficacy and Safety of Eribulin in the Treatment of Advanced Breast CancerNCT04683445
Breast Cancer
Eribulin
Trastuzumab
pertuzumab
Pyrotinib
Pembrolizumab
Camerlizumab
18 Years - 80 YearsSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Real-world Study of Pyrotinib in Neoadjuvant Therapy for HER2-positive Breast CancerNCT05561686
HER2-positive B...
Pyrotinib
18 Years - 65 YearsHunan Cancer Hospital
Pyrotinib Combined With Capecitabine Metronomic Therapy in HER2-postitive Advanced Breast CancerNCT03923166
Breast Cancer
Pyrotinib
capecitabine
18 Years - 75 YearsChineseAMS
Neoadjuvant Chemotherapy With Pyrotinib, Epirubicin and Cyclophosphamide Followed by Taxanes and Trastuzumab for HER-2+ Breast CancerNCT04290793
Breast Cancer
Pyrotinib
Epirubicin
Cyclophosphamid...
Taxanes
Trastuzumab
18 Years - 65 YearsHebei Medical University Fourth Hospital
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