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Brief Title: Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population
Official Title: Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population Treated With Immune Checkpoint Inhibitors for Various Cancers
Study ID: NCT05863052
Brief Summary: The aim of this study is to describe the outcomes in American Indian patients receiving immunotherapy in a multi-institution retrospective study at several other high-volume centers that care for this patient population and to identify any healthcare disparities that can lead to future interventional studies.
Detailed Description: Immune checkpoint inhibitors have been shown to increase survival in metastatic solid tumor patients when compared to the previously standard of care chemotherapy. Epidemiologic studies of American Indian cancer patients demonstrated having significantly worse survival when compared with Caucasians when controlled for age, sex, alcohol abuse, smoking, insurance, and disease stage. There are no current studies specifically examining the American Indian population receiving treatment with immune checkpoint inhibitors. The aim is to describe the outcomes in American Indian patients receiving immunotherapy in a multi-institution retrospective study at several other high-volume centers that care for this patient population and to identify any healthcare disparities that can lead to future interventional studies.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Arizona Cancer Center at the Unvieristy of Arizona, Tucson, Arizona, United States
University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico, United States
Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Monument Health Cancer Care Institute, Rapid City, South Dakota, United States
Avera Cancer Institute, Sioux Falls, South Dakota, United States
Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah, United States
Name: Abdul Naqash, MD
Affiliation: University of Oklahoma
Role: PRINCIPAL_INVESTIGATOR