Spots Global Cancer Trial Database for squamous cell carcinoma
Every month we try and update this database with for squamous cell carcinoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer | NCT00409565 | Head and Neck C... Squamous Cell C... | Cetuximab Bevacizumab | 18 Years - 98 Years | National Cancer Institute (NCI) | |
Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer | NCT00364715 | Squamous Cell C... | 26 Years - 85 Years | National Taiwan University Hospital | ||
A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck | NCT04435938 | Head and Neck N... Squamous Cell C... Squamous Skin C... | Stereotactic Bo... | 60 Years - | McMaster University | |
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2). | NCT04472429 | Squamous Cell C... | carboplatin paclitaxel retifanlimab | 18 Years - | Incyte Corporation | |
Sexual Behavior in Head and Neck Cancer Patients | NCT00662662 | Oropharyngeal C... Head and Neck C... Squamous Cell C... | Questionnaire | 18 Years - | M.D. Anderson Cancer Center | |
Ex-vivo Examination of Excisions of Skin Tumors by Confocal Optical Coherence Tomography (LC-OCT) With Integrated Dermoscopy and Comparison With Histology (DERMOCTAV) | NCT05340543 | Cutaneous Tumor Optical Coheren... Basal Cell Carc... Squamous Cell C... Melanoma | Confocal optica... | 18 Years - | Ramsay Générale de Santé | |
Study of Induction Docetaxel, Cisplatin and 5-Fluorouracil | NCT00400205 | Squamous Cell C... Oral Cancer | Docetaxel Cisplatin 5-fluorouracil | 18 Years - | Emory University | |
Zalutumumab in Combination With Radiotherapy in Head and Neck Cancer Patients Ineligible for Platinum Based Chemotherapy | NCT00707655 | Head and Neck C... Squamous Cell C... | Zalutumumab | 18 Years - | Genmab | |
Nedaplatin (Jiebaishu®) Combined With Docetaxel for Advanced Lung Squamous Cell Carcinoma | NCT02088515 | Squamous Cell C... | Nedaplatin Cisplatin Docetaxel | 18 Years - 75 Years | Jiangsu Simcere Pharmaceutical Co., Ltd. | |
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours | NCT05605522 | Pancreatic Duct... Squamous Cell C... Colorectal Canc... Gastric Cancer Ewing Sarcoma NTSR1 Expressin... Neuroendocrine ... | [225]-FPI-2059 [111In]-FPI-205... | 18 Years - | Fusion Pharmaceuticals Inc. | |
Electronic Brachytherapy for the Treatment of NMSC | NCT01016899 | Basal Cell Carc... Squamous Cell C... | electronic brac... | 50 Years - | Xoft, Inc. | |
Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma | NCT05070403 | Squamous Cell C... | Afatinib 40 MG | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
Cetuximab in Head and Neck Cancer Patients | NCT03769311 | Head and Neck C... Squamous Cell C... | Cetuximab | 18 Years - | University of Wisconsin, Madison | |
Study of TVEC in Patients With Cutaneous Squamous Cell Cancer | NCT03714828 | Squamous Cell C... Skin Cancer Keratoacanthoma Cutaneous Tumor Skin Cancer, Sq... Lesion Skin | Injection of TV... Injection of TV... Injection of TV... Injection of TV... | 18 Years - | University of Arizona | |
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | NCT03190174 | Ewing Sarcoma PEComa Epithelioid Sar... Desmoid Tumor Chordoma Non Small Cell ... Urothelial Carc... Melanoma Renal Cell Carc... Squamous Cell C... Hepatocellular ... Classical Hodgk... Colorectal Canc... MTOR Activating... | Nab-Rapamycin Nivolumab | 12 Years - | Sarcoma Oncology Research Center, LLC | |
Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck | NCT03708224 | Cancer Carcinoma Squamous Cell C... Head and Neck C... | Atezolizumab Tocilizumab Tiragolumab | 18 Years - | University of California, San Francisco | |
Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN) | NCT04606940 | Head and Neck C... Advanced Cancer Metastatic Canc... HNSCC Squamous Cell C... | 18 Years - | University Health Network, Toronto | ||
Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT) | NCT01511081 | Non-small-cell ... | SBRT (stereotac... SBPT (stereotac... | 18 Years - | M.D. Anderson Cancer Center | |
Study for Treatment of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Skin | NCT02449681 | Metastatic Head... | TH-4000 (Tarlox... | 18 Years - | Rain Oncology Inc | |
Study of BKM120 in Advanced Squamous Cell Carcinoma of Head and Neck | NCT01527877 | Head Neck Cance... Head Neck Cance... | BKM120 | 20 Years - 80 Years | Yonsei University | |
Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN | NCT02124707 | Head and Neck C... Squamous Cell C... | Cetuximab Paclitaxel Carboplatin | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial | NCT01512589 | Esophageal Canc... | Proton Beam The... Intensity Modul... Questionnaires | 18 Years - | M.D. Anderson Cancer Center | |
Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma | NCT02549638 | Carcinoma, Squa... Carcinoma, Squa... Squamous Cell C... Lung Neoplasms Cancer of Lung Cancer of the L... Lung Cancer Neoplasms, Lung Neoplasms, Pulm... Pulmonary Cance... Pulmonary Neopl... | DNA Extraction | 18 Years - | Mayo Clinic | |
Pembrolizumab in Combination With CRT for LA-SCCHN | NCT02586207 | Head and Neck C... Squamous Cell C... Oral Cavity Can... Oropharynx Canc... Hypopharynx Can... Larynx Cancer Laryngeal Cance... | pembrolizumab (... Cisplatin Radiation | 18 Years - | Sanford Health | |
DNX-2440 for Resectable Colorectal Liver Metastasis | NCT04714983 | Liver Metastase... Liver Metastasi... Colorectal Canc... Breast Cancer Gastric Cancer Periampullary C... Melanoma Renal Cell Canc... Sarcoma Squamous Cell C... Gastrointestina... | DNX-2440 | 18 Years - | DNAtrix, Inc. | |
Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery | NCT01298167 | Basal Cell Carc... Squamous Cell C... | Cyanoacrylate t... | 18 Years - | Yale University | |
Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer | NCT01363466 | Stage IB2 Cervi... Stage II Cervic... Adenocarcinoma Squamous Cell C... Adenosquamous C... | hysterectomy | 18 Years - 70 Years | UNICANCER | |
Study to Calculate the Radiation Dosimetry in Subjects With Head and Neck Cancer | NCT00245349 | Head and Neck C... | F-18 Fluorothym... | 21 Years - | University of Iowa | |
DERM US and EU Validation Study | NCT05126173 | Malignant Skin ... Basal Cell Carc... Squamous Cell C... | Deep Ensemble f... | 18 Years - | Skin Analytics Limited | |
A Clinical Study to Assess the Efficacy and Safety of Alpha DaRT224 for the Treatment of Patients With Recurrent Cutaneous Squamous Cell Carcinoma | NCT05323253 | Recurrent Squam... | DaRT seeds | 18 Years - | Alpha Tau Medical LTD. | |
Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole | NCT00038038 | Squamous Cell C... Head and Neck N... Metastases, Neo... | 18F-fluoromison... PET scan | 18 Years - | M.D. Anderson Cancer Center | |
Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer | NCT03215810 | Non-Small Cell ... Metastatic Non-... Squamous Cell C... Advanced NSCLC Adenosquamous C... Adenocarcinomas | Tumor-infiltrat... Nivolumab Cyclophosphamid... Fludarabine Tumor-infiltrat... Interleukin-2 (... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer | NCT03237325 | Squamous Cell C... Oral Mucositis | SGX942 Placebo | 18 Years - | Soligenix | |
Dendritic Cell Vaccine for Head and Neck Cancer | NCT00492947 | Squamous Cell C... | dendritic cell ... | 18 Years - | University of Maryland, Baltimore | |
Topical Ascorbic Acid for Treatment of Squamous Cell Skin Cancer | NCT05932511 | Squamous Cell C... Squamous Cell C... Skin Cancer Non-melanoma Sk... | 30% ascorbic ac... | 18 Years - 85 Years | Center for Biomedical Research, Inc. | |
Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors. | NCT05072327 | Eyelid Tumor | Mohs surgery cryotherapy | - | Sun Yat-sen University | |
A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 | NCT03058289 | Breast Cancer Head and Neck C... Squamous Cell C... Lymphoma Pancreatic Canc... Liver Cancer Colon Cancer Lung Cancer Bile Duct Cance... Chordoma of Sac... Sarcoma | INT230-6 anti-PD-1 antib... anti-CTLA-4 ant... | 18 Years - | Intensity Therapeutics, Inc. | |
The Impact of Total Body Skin Examination on Skin Cancer Detection | NCT00765193 | Melanoma Basal Cell Carc... Squamous Cell C... Merkel Cell Car... Skin Cancer | Inspection of c... | 18 Years - 95 Years | Medical University of Graz | |
Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced Oropharyngeal Cancer Undergoing Chemoradiation Therapy | NCT03611205 | Oropharyngeal S... HPV Positive Or... | Computed Tomogr... Positron Emissi... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients | NCT03689712 | Oral Mucositis | GC4419 90mg Placebo | 18 Years - | Galera Therapeutics, Inc. | |
Teripalimab Plus Chemotherapy in Local Advanced Esophageal Cancer | NCT03985670 | Squamous Cell C... Esophageal Canc... Perioperative P... | teripalimab plu... chemotherapy pl... | 18 Years - 70 Years | Henan Cancer Hospital | |
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia | NCT04534127 | Skin Cancer Mucosal Neoplas... Soft Tissue Neo... | Radiation: Diff... | 18 Years - | Alpha Tau Medical LTD. | |
Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040) | NCT02252042 | Head and Neck S... | Pembrolizumab Methotrexate Docetaxel Cetuximab | 18 Years - | Merck Sharp & Dohme LLC | |
Cemiplimab/Peg-Interferon-α in Advanced CSCC | NCT05729139 | Cutaneous Squam... Squamous Cell C... Advanced Squamo... | Cemiplimab-Rwlc PEG-IFN alfa-2a | 18 Years - | Baptist Health South Florida | |
Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer | NCT01607905 | Solid Tumor | Selinexor Acetaminophen | 18 Years - | Karyopharm Therapeutics Inc | |
Azacitidine and Cisplatin for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck | NCT00443261 | Squamous Cell C... | Azacitidine Cisplatin | 18 Years - | University of Kansas Medical Center | |
Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology | NCT03462524 | Esophageal Canc... Radiation Pneum... Pulmonary Fibro... Respiratory Fai... Pneumonia Surgery Chemotherapy Ef... Radiation Fibro... Radiation Toxic... Adenocarcinoma Squamous Cell C... | Esophagectomy | 18 Years - | St. James's Hospital, Ireland | |
An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037 | NCT00884520 | Lung Cancer Squamous Cell C... Head and Neck C... Hepatic Carcino... Renal Cell Carc... | [F-18] VM4-037 | 18 Years - | Siemens Molecular Imaging | |
Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy | NCT04106167 | Advanced Solid ... Lymphoma Gastric Cancer Colorectal Canc... Head and Neck C... Squamous Cell C... EGFR Positive S... HER2-positive B... Hepatocellular ... Small-cell Lung... Renal Cell Carc... Pancreas Cancer Melanoma NSCLC Urothelial Carc... Cervical Cancer Microsatellite ... Merkel Cell Car... | Allogeneic natu... | 18 Years - | Fate Therapeutics | |
A Phase I/II Clinical Trial of PepCan in Head and Neck Cancer Patients | NCT03821272 | Head and Neck C... | PepCan Placebo | 18 Years - 100 Years | University of Arkansas | |
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2). | NCT04472429 | Squamous Cell C... | carboplatin paclitaxel retifanlimab | 18 Years - | Incyte Corporation | |
THIO Sequenced With Cemiplimab in Advanced NSCLC | NCT05208944 | Carcinoma, Non-... | 6-Thio-2'-Deoxy... Cemiplimab | 18 Years - | Maia Biotechnology | |
Photodynamic Therapy (PDT) With Temoporfin for Non-Resectable Non-Small-Cell Lung Cancer | NCT01637376 | Carcinoma, Non-... | Temoporfin | 18 Years - | University of Arkansas | |
Specific Methylation Profiles in HNSCC | NCT04567056 | Head and Neck S... | Blood sample | 18 Years - | Aalborg University Hospital | |
Pembrolizumab Plus Olaparib in LA-HNSCC | NCT05366166 | Squamous Cell C... | Pembrolizumab Olaparib Cisplatin IMRT (intensity... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC | NCT05047094 | Head and Neck S... Skin Cancer Metastatic Head... | Diffusing Alpha... Pembrolizumab | 18 Years - | Alpha Tau Medical LTD. | |
IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas | NCT04224389 | Squamous Cell C... | transoral resec... IMRT | 18 Years - | Gustave Roussy, Cancer Campus, Grand Paris | |
Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma | NCT03422536 | Head and Neck B... Recurrent Head ... Recurrent Oroph... Squamous Cell C... Stage IV Squamo... Stage IV Squamo... Stage IV Nasoph... Stage IV Oropha... Stage IVA Lip a... Stage IVA Nasal... Stage IVA Nasop... Stage IVA Oroph... Stage IVB Lip a... Stage IVB Nasal... Stage IVB Nasop... Stage IVB Oroph... Stage IVC Lip a... Stage IVC Nasal... Stage IVC Nasop... Stage IVC Oroph... Head and Neck C... Oropharyngeal C... HNSCC Stage IV Lip an... | Cetuximab Ficlatuzumab | 18 Years - | University of Arizona | |
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors | NCT04889742 | Recurrent Cance... Prostate Cancer Cervical Cancer Anal Cancer Sarcoma Rectal Cancer Neuroendocrine ... Esophageal Canc... Pancreas Cancer Squamous Cell C... | loco-regional h... | 18 Years - | Charite University, Berlin, Germany | |
Paclitaxel, Carboplatin And Low Dose Radiation As Induction Therapy In Locally Advanced Head And Neck Cancer | NCT00176267 | Squamous Cell C... | Radiotherapy Paclitaxel Carboplatin | 18 Years - | University of Kentucky | |
Retreatment With Intratumoral Diffusing Alpha Radiation Emitters | NCT04540588 | Skin Cancer Mucosal Neoplas... Soft Tissue Neo... | Radiation: Diff... | 18 Years - | Alpha Tau Medical LTD. | |
Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer | NCT01445405 | Carcinoma, Squa... Head and Neck C... Oral Cancer Laryngeal Cance... Pharyngeal Canc... | Bortezomib (Vel... Cetuximab Cisplatin Radiation Thera... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | |
Isolating and Testing Circulating Tumor DNA and Soluble Immune Markers During the Course of Treatment for Lung Cancer | NCT02410603 | Lung Cancer Lung Neoplasms Cancer of Lung Cancer of the L... Neoplasms, Lung Neoplasms, Pulm... Pulmonary Cance... Pulmonary Neopl... Carcinoma, Non-... Adenocarcinoma Squamous Cell C... | 18 Years - | Mayo Clinic | ||
Clinical vAlidation of a MobilE appLication ("ProRodinki") in the Assessment of the maLignant skIn neoplAsms | NCT05402046 | Melanoma (Skin) Nevus Nevus, Spitz Nevus Halo Nevus, Pigmente... Basal Cell Carc... Squamous Cell C... Bowen's Disease Melanoma in Sit... Spot Pigmented | Mobile phone ap... | 18 Years - | MelanomaPRO, Russia | |
Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population | NCT05863052 | Immune Checkpoi... Metastatic Soli... Nonsmall Cell L... Melanoma Renal Cell Carc... Gastrointestina... Squamous Cell C... | Immunotherapy | 18 Years - 99 Years | University of Oklahoma | |
Zalutumumab in Combination With Radiotherapy in Head and Neck Cancer Patients Ineligible for Platinum Based Chemotherapy | NCT00707655 | Head and Neck C... Squamous Cell C... | Zalutumumab | 18 Years - | Genmab | |
Pilot Study of PDL to Treat BCC and SCCIS | NCT01245972 | Basal Cell Carc... Squamous Cell C... | PDL Treatment | 18 Years - | University of California, San Diego | |
A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers | NCT04260802 | Cancer Neoplasms Metastatic Canc... Triple Negative... Gastric Cancer Cervical Cancer Ovarian Cancer Hepatocellular ... Squamous Cell C... Urothelial Carc... Urothelial Neop... Non Small Cell ... Renal Cell Carc... Locally Advance... Locally Advance... Squamous Cell C... Sarcoma Merkel Cell Car... Bladder Cancer | OC-001 OC-001 in Combi... | 18 Years - | Ocellaris Pharma, Inc. | |
Spectroscopy With Surface Coils and Decoupling | NCT00581815 | Adrenal Cortica... Brain Cancer Breast Cancer CNS Cancer Colon Cancer HEENT Cancer Hodgkin's Disea... Kaposi's Sarcom... Liver Cancer Lung Cancer Non-Hodgkin's L... Ovarian Cancer Pancreatic Canc... Prostate Cancer Rectal Cancer Renal Cancer Sarcoma Squamous Cell C... Thyroid Cancer | Proton-decouple... 1H Spectroscopy... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
Surgical Margin Assessment by 3D Ultrasound | NCT05740774 | Tongue Cancer Squamous Cell C... Head and Neck C... | 3D ultrasound | 18 Years - | Rigshospitalet, Denmark | |
Trimodality Management of T1b Esophageal Cancers | NCT01217060 | Esophageal Canc... | Docetaxel 5-FU Radiotherapy Esophagectomy Dexamethasone | 18 Years - | M.D. Anderson Cancer Center | |
Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer | NCT00094081 | Head and Neck N... | tirapazamine (S... cisplatin Radiation Thera... | 18 Years - | Sanofi | |
Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins | NCT01872130 | Basal Cell Carc... Squamous Cell C... | 18 Years - | Memorial Sloan Kettering Cancer Center | ||
Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients | NCT00201383 | Oral Cavity Squamous Cell C... | cisplatin | - | National Health Research Institutes, Taiwan | |
De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca | NCT01530997 | Carcinoma, Squa... Head and Neck N... Oropharyngeal N... | Intensity Modul... Cisplatin Limited surgica... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
Pembrolizumab in Combination With Cisplatin and Intensity Modulated Radiotherapy (IMRT) in Head and Neck Cancer | NCT02777385 | Head and Neck S... | Pembrolizumab Cisplatin IMRT | 18 Years - | University of Pittsburgh | |
Nanocytology Test to Evaluate Skin Cancer in High Risk Patients | NCT01905891 | Actinic Keratos... Squamous Cell C... | Superficial sha... | 18 Years - 89 Years | Northwestern University | |
Study of Anlotinib Plus Chemotherapy as the First-line Treatment in Patients With Advanced NSCLC | NCT03636685 | NSCLC Adenocarcinoma Squamous Cell C... | Anlotinib combi... Anlotinib combi... Anlotinib combi... Anlotinib combi... | 18 Years - 70 Years | ChineseAMS | |
Phase I Study of Olaparib Combined With Cisplatin-based Chemoradiotherapy to Treat Locally Advanced Head and Neck Cancer | NCT02308072 | Head and Neck C... | Olaparib Cisplatin IMRT | 18 Years - | University College, London | |
Surgical Margin Assessment by 3D Ultrasound | NCT05740774 | Tongue Cancer Squamous Cell C... Head and Neck C... | 3D ultrasound | 18 Years - | Rigshospitalet, Denmark |