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Brief Title: The Effect of Late-evening Snacks on Patients With Primary Hepatocellular Carcinoma After Hepatectomy
Official Title: Effects of Late-evening Snacks on Nutritional Status and Metabolic Pattern of Patients With Primary Hepatocellular Carcinoma After Hepatectomy
Study ID: NCT06278701
Brief Summary: Late-evening snacks, in which a portion of food is moved to bedtime while the total amount of food eaten per day remains unchanged, can effectively improve the metabolic state of accelerated catabolism. The goal of this clinical trial is to learn about the effects of late-evening snacks on health conditions of hepatocellular carcinoma patients who underwent hepatectomy, and to further explore the effects of late-evening snacks on patients' metabolic patterns. The main question it aims to answer are: • the effect of late-evening snacks on the nutritional status of hepatic resection patients with hepatocellular carcinoma; * the effect of late-evening snacks on the recovery of liver function in liver cancer hepatectomy patients; * the effect of late-evening snacks on the complication rate of hepatic resection patients with hepatocellular carcinoma; * the effect of late-evening snacks on long-term quality of life of hepatic resection patients with hepatocellular carcinoma; * the effect of late-evening snacks on the metabolic pattern of hepatic resection patients with hepatocellular carcinoma. After learning about the 2 dietary modalities of the late-evening snacks and regular diet, patients will be placed in the different groups according to your preference. Patients who enter the test group will have additional meal 1h before bedtime every day, while patients in the control group will have normal diet. Patients will be asked to : * eat 1h before bedtime; * follow the doctor's instructions during their stay in the hospital; * have follow-up examinations at 1 month, 3 months and 6 months after the operation, after which blood samples will be collected for metabolite testing.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China
Name: Yao Du, Master
Affiliation: Drum Tower Hospital, Medical School of Nanjing University
Role: STUDY_DIRECTOR