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Spots Global Cancer Trial Database for Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

Official Title: Observational - Tissue Factor Expression in Bone Sarcomas

Study ID: NCT01807052

Study Description

Brief Summary: This trial studies biomarker expression in tissue samples from patients with bone sarcomas. Studying biomarker in tissue samples from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer

Detailed Description: STUDY SUBTYPE: Ancillary/Correlative OBSERVATIONAL STUDY MODEL: Case-only TIME PERSPECTIVE: Retrospective BIOSPECIMEN RETENTION: Samples without DNA BIOSPECIMEN DESCRIPTION: Tissue samples obtained from Cooperative Human Tissue Network (CHTN) STUDY POPULATION DESCRIPTION: Patients enrolled on P9754 and AOST0121 clinical trials SAMPLING METHOD: Non-probability sample PRIMARY OBJECTIVES: I. To determine if there is differential expression of tumor factor (TF) among patients with osteosarcoma. II. To determine if there is an association between overall survival and disease free survival and the extent of TF expression. III. To determine if TF expression correlates with presence of gross metastatic disease at presentation, and development of subsequent metastases. OUTLINE: Tissue samples are analyzed for tumor factor expression levels by immunohistochemistry.

Keywords

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Children's Oncology Group, Monrovia, California, United States

Contact Details

Name: Mark Ranalli, MD

Affiliation: Children's Oncology Group

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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