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Spots Global Cancer Trial Database for metastatic osteosarcoma

Every month we try and update this database with for metastatic osteosarcoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With OsteosarcomaNCT05235165
Metastatic Mali...
Metastatic Oste...
Osteosarcoma
Biospecimen Col...
Computed Tomogr...
Questionnaire A...
Thoracoscopy
Thoracotomy
- 50 YearsChildren's Oncology Group
Ecteinascidin 743 in Treating Patients With Previously Treated Metastatic OsteosarcomaNCT00005625
Sarcoma
trabectedin
12 Years - Memorial Sloan Kettering Cancer Center
Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent OsteosarcomaNCT02484443
Metastatic Mali...
Metastatic Oste...
Recurrent Osteo...
Dinutuximab
Laboratory Biom...
Pharmacological...
Sargramostim
- 29 YearsNational Cancer Institute (NCI)
Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With OsteosarcomaNCT01374672
Localized Osteo...
Metastatic Oste...
Osteoblastic Os...
Recurrent Osteo...
laboratory biom...
10 Years - 20 YearsChildren's Oncology Group
Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By SurgeryNCT01553539
Bone Cancer
Chondrosarcoma
Clear Cell Sarc...
Metastatic Oste...
Ovarian Sarcoma
Recurrent Adult...
Recurrent Osteo...
Recurrent Uteri...
Stage III Adult...
Stage III Uteri...
Stage IV Adult ...
Stage IV Uterin...
therapeutic ang...
laboratory biom...
18 Years - Wake Forest University Health Sciences
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the LungsNCT06228326
Lung Cancer, No...
Lung Cancer Met...
Solid Tumor, Ad...
Advanced Cancer
Lung Cancer, Sm...
Metastatic Colo...
Metastatic Rena...
Metastatic Hepa...
Metastatic Sarc...
Metastatic Oste...
KB707
18 Years - Krystal Biotech, Inc.
Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic SarcomaNCT04668300
Metastatic Angi...
Metastatic Dedi...
Metastatic Oste...
Recurrent Angio...
Recurrent Dedif...
Recurrent Osteo...
Refractory Dedi...
Refractory Oste...
Durvalumab
Oleclumab
12 Years - M.D. Anderson Cancer Center
Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the BrainNCT00550654
Kidney Cancer
Melanoma (Skin)
Metastatic Canc...
Ovarian Cancer
Sarcoma
Unspecified Adu...
questionnaire a...
3-dimensional c...
hypofractionate...
image-guided ra...
tomotherapy
18 Years - National Institutes of Health Clinical Center (CC)
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic OsteosarcomaNCT00742924
Sarcoma
cisplatin
dexrazoxane hyd...
doxorubicin hyd...
etoposide
ifosfamide
leucovorin calc...
methotrexate
zoledronic acid
adjuvant therap...
neoadjuvant the...
therapeutic con...
filgrastim
Mesna
- 40 YearsChildren's Oncology Group
Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone SarcomaNCT01016015
Metastatic Oste...
Recurrent Adult...
Recurrent Osteo...
Stage III Adult...
Stage IV Adult ...
Cixutumumab
Laboratory Biom...
Temsirolimus
16 Years - National Cancer Institute (NCI)
Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic OsteosarcomaNCT00003776
Sarcoma
filgrastim
cisplatin
doxorubicin hyd...
ifosfamide
leucovorin calc...
methotrexate
trimetrexate gl...
surgical proced...
- 30 YearsMemorial Sloan Kettering Cancer Center
Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic OsteosarcomaNCT01062438
Sarcoma
DNA analysis
RNA analysis
gene expression...
gene rearrangem...
mutation analys...
laboratory biom...
- Children's Oncology Group
Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk OsteosarcomaNCT01886105
Metastatic Oste...
Sm-EDTMP
Autologous Stem...
External Beam R...
10 Years - 65 YearsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable OsteosarcomaNCT01804374
Metastatic Oste...
Relapsed Osteos...
Sorafenib
Everolimus
18 Years - Italian Sarcoma Group
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed OsteosarcomaNCT05691478
High Grade Oste...
Localized Osteo...
Metastatic Oste...
Secondary Osteo...
Bone Scan
Cabozantinib S-...
Cisplatin
Computed Tomogr...
Doxorubicin Hyd...
Magnetic Resona...
Methotrexate
Surgical Proced...
X-Ray Imaging
- 40 YearsNational Cancer Institute (NCI)
Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of OsteosarcomaNCT00066365
Metastatic Canc...
Sarcoma
sargramostim
conventional su...
- 39 YearsChildren's Oncology Group
Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With OsteosarcomaNCT00245011
Sarcoma
filgrastim
ifosfamide
peripheral bloo...
Sm-EDTMP (low d...
sm-EDTMP (highe...
13 Years - 50 YearsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic OsteosarcomaNCT01062438
Sarcoma
DNA analysis
RNA analysis
gene expression...
gene rearrangem...
mutation analys...
laboratory biom...
- Children's Oncology Group
Interferon Alfa and Thalidomide in Treating Patients With Soft Tissue Sarcoma or Bone SarcomaNCT00026416
Sarcoma
recombinant int...
thalidomide
adjuvant therap...
18 Years - National Cancer Institute (NCI)
Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By SurgeryNCT01553539
Bone Cancer
Chondrosarcoma
Clear Cell Sarc...
Metastatic Oste...
Ovarian Sarcoma
Recurrent Adult...
Recurrent Osteo...
Recurrent Uteri...
Stage III Adult...
Stage III Uteri...
Stage IV Adult ...
Stage IV Uterin...
therapeutic ang...
laboratory biom...
18 Years - Wake Forest University Health Sciences
Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing SarcomaNCT02243605
Metastatic Ewin...
Metastatic Oste...
Recurrent Ewing...
Recurrent Osteo...
Stage III Osteo...
Stage IV Osteos...
Stage IVA Osteo...
Stage IVB Osteo...
Unresectable Ew...
Unresectable Os...
Cabozantinib S-...
Laboratory Biom...
12 Years - National Cancer Institute (NCI)
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid TumorsNCT05135975
Neuroblastoma
Sarcoma
Cabozantinib
18 Months - 40 YearsNationwide Children's Hospital
Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for CancerNCT01132547
Cancer
cyproheptadine ...
placebo
2 Years - 21 YearsUniversity of South Florida
Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic OsteosarcomaNCT00023998
Metastatic Oste...
doxorubicin hyd...
cisplatin
methotrexate
leucovorin calc...
filgrastim
therapeutic con...
radiation thera...
etoposide
ifosfamide
trastuzumab
laboratory biom...
- 30 YearsNational Cancer Institute (NCI)
Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic OsteosarcomaNCT01062438
Sarcoma
DNA analysis
RNA analysis
gene expression...
gene rearrangem...
mutation analys...
laboratory biom...
- Children's Oncology Group
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic OsteosarcomaNCT00742924
Sarcoma
cisplatin
dexrazoxane hyd...
doxorubicin hyd...
etoposide
ifosfamide
leucovorin calc...
methotrexate
zoledronic acid
adjuvant therap...
neoadjuvant the...
therapeutic con...
filgrastim
Mesna
- 40 YearsChildren's Oncology Group
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyNCT00716976
Brain Tumor
Central Nervous...
Childhood Germ ...
Extragonadal Ge...
Liver Cancer
Neuroblastoma
Ototoxicity
Ovarian Cancer
Sarcoma
sodium thiosulf...
examination
1 Year - 18 YearsChildren's Oncology Group
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid TumorsNCT05135975
Neuroblastoma
Sarcoma
Cabozantinib
18 Months - 40 YearsNationwide Children's Hospital
Biomarker Expression in Tissue Samples From Patients With Bone SarcomasNCT01807052
Localized Osteo...
Metastatic Oste...
Recurrent Osteo...
laboratory biom...
- 39 YearsChildren's Oncology Group
Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the BrainNCT00550654
Kidney Cancer
Melanoma (Skin)
Metastatic Canc...
Ovarian Cancer
Sarcoma
Unspecified Adu...
questionnaire a...
3-dimensional c...
hypofractionate...
image-guided ra...
tomotherapy
18 Years - National Institutes of Health Clinical Center (CC)
Alanosine in Treating Patients With CancerNCT00062283
Lung Cancer
Malignant Mesot...
Pancreatic Canc...
Sarcoma
L-alanosine
13 Years - National Cancer Institute (NCI)
Ecteinascidin 743 in Treating Patients With Previously Treated Metastatic OsteosarcomaNCT00005625
Sarcoma
trabectedin
12 Years - Memorial Sloan Kettering Cancer Center
Interferon Alfa and Thalidomide in Treating Patients With Soft Tissue Sarcoma or Bone SarcomaNCT00026416
Sarcoma
recombinant int...
thalidomide
adjuvant therap...
18 Years - National Cancer Institute (NCI)
Study of Blood Samples From Patients With OsteosarcomaNCT00954473
Localized Osteo...
Metastatic Oste...
Recurrent Osteo...
laboratory biom...
- Children's Oncology Group
Indo-cyanine Green (ICG) in Paediatric Oncology MISNCT04854018
Pediatric Renal...
Metastatic Oste...
Metastatic Ewin...
Pulmonary Metas...
Rhabdomyosarcom...
Non-Rhabdo. Sof...
Indocyanine gre...
1 Day - 15 YearsBirmingham Women's and Children's NHS Foundation Trust
Monoclonal Antibody A1G4 Plus BCG in Treating Patients With CancerNCT00003023
Neuroblastoma
Sarcoma
BCG vaccine
monoclonal anti...
- Memorial Sloan Kettering Cancer Center
Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With OsteosarcomaNCT00134030
Localized Osteo...
Metastatic Oste...
Cisplatin
Doxorubicin Hyd...
Etoposide
Ifosfamide
Methotrexate
Peginterferon A...
Quality-of-Life...
Questionnaire A...
Therapeutic Con...
5 Years - 40 YearsChildren's Oncology Group
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