Spots Global Cancer Trial Database for A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
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Trial Identification
Brief Title: A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Official Title: A Phase III, Randomized, Open-Label, Multi-Center, Global Study of Volrustomig (MEDI5752) as Sequential Therapy Versus Observation in Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma, Who Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (eVOLVE-HNSCC)
Study ID: NCT06129864
Interventions
Study Description
Brief Summary: The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT).
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Birmingham, Alabama, United States
Research Site, Prescott Valley, Arizona, United States
Research Site, Springdale, Arkansas, United States
Research Site, Los Angeles, California, United States
Research Site, Orange, California, United States
Research Site, San Francisco, California, United States
Research Site, Santa Rosa, California, United States
Research Site, Aurora, Colorado, United States
Research Site, Lone Tree, Colorado, United States
Research Site, Gainesville, Florida, United States
Research Site, Miami, Florida, United States
Research Site, Palm Bay, Florida, United States
Research Site, West Palm Beach, Florida, United States
Research Site, Niles, Illinois, United States
Research Site, Des Moines, Iowa, United States
Research Site, Kansas City, Kansas, United States
Research Site, Louisville, Kentucky, United States
Research Site, Baton Rouge, Louisiana, United States
Research Site, Shreveport, Louisiana, United States
Research Site, Baltimore, Maryland, United States
Research Site, Columbia, Maryland, United States
Research Site, Hyattsville, Maryland, United States
Research Site, Towson, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Minneapolis, Minnesota, United States
Research Site, Columbia, Missouri, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Saint Louis, Missouri, United States
Research Site, East Brunswick, New Jersey, United States
Research Site, Hackensack, New Jersey, United States
Research Site, New Brunswick, New Jersey, United States
Research Site, Albuquerque, New Mexico, United States
Research Site, New York, New York, United States
Research Site, Stony Brook, New York, United States
Research Site, Charlotte, North Carolina, United States
Research Site, Winston-Salem, North Carolina, United States
Research Site, Cleveland, Ohio, United States
Research Site, Portland, Oregon, United States
Research Site, Portland, Oregon, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, York, Pennsylvania, United States
Research Site, Nashville, Tennessee, United States
Research Site, Austin, Texas, United States
Research Site, Dallas, Texas, United States
Research Site, Flower Mound, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Odessa, Texas, United States
Research Site, Tyler, Texas, United States
Research Site, Salt Lake City, Utah, United States
Research Site, West Jordan, Utah, United States
Research Site, Fairfax, Virginia, United States
Research Site, Norfolk, Virginia, United States
Research Site, Richmond, Virginia, United States
Research Site, Spokane, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Innsbruck, , Austria
Research Site, Linz, , Austria
Research Site, Salzburg, , Austria
Research Site, Wien, , Austria
Research Site, Charleroi, , Belgium
Research Site, Edegem, , Belgium
Research Site, Jette, , Belgium
Research Site, Barretos, , Brazil
Research Site, Florianópolis, , Brazil
Research Site, Fortaleza, , Brazil
Research Site, Ijuí, , Brazil
Research Site, Ipatinga, , Brazil
Research Site, Londrina, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Ribeirão Preto, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Teresina, , Brazil
Research Site, Edmonton, Alberta, Canada
Research Site, Kelowna, British Columbia, Canada
Research Site, Kingston, Ontario, Canada
Research Site, London, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Avignon Cedex 09, , France
Research Site, Bordeaux, , France
Research Site, Lyon, , France
Research Site, Saint Herblain, , France
Research Site, Toulouse Cedex 09, , France
Research Site, Villejuif, , France
Research Site, Berlin, , Germany
Research Site, Essen, , Germany
Research Site, Greifswald, , Germany
Research Site, Hamburg, , Germany
Research Site, Hannover, , Germany
Research Site, Lübeck, , Germany
Research Site, München, , Germany
Research Site, Rostock, , Germany
Research Site, Tübingen, , Germany
Research Site, Ulm, , Germany
Research Site, Würzburg, , Germany
Research Site, Budapest, , Hungary
Research Site, Budapest, , Hungary
Research Site, Budapest, , Hungary
Research Site, Győr, , Hungary
Research Site, Kecskemét, , Hungary
Research Site, Miskolc, , Hungary
Research Site, Nyíregyháza, , Hungary
Research Site, Pécs, , Hungary
Research Site, Szekszárd, , Hungary
Research Site, Bengaluru, , India
Research Site, Hyderabad, , India
Research Site, Jaipur, , India
Research Site, Kochi, , India
Research Site, Kolkata, , India
Research Site, Lucknow, , India
Research Site, Madurai, , India
Research Site, Mohali, , India
Research Site, New Delhi, , India
Research Site, Thiruvananthapuram, , India
Research Site, Vadodara, , India
Research Site, Varanasi, , India
Research Site, Aviano, , Italy
Research Site, Firenze, , Italy
Research Site, Milano, , Italy
Research Site, Modena, , Italy
Research Site, Napoli, , Italy
Research Site, Padova, , Italy
Research Site, Pavia, , Italy
Research Site, Rozzano, , Italy
Research Site, Bunkyo-ku, , Japan
Research Site, Chiba-shi, , Japan
Research Site, Chuo-ku, , Japan
Research Site, Fukuoka, , Japan
Research Site, Hiroshima-shi, , Japan
Research Site, Kashiwa, , Japan
Research Site, Kobe-shi, , Japan
Research Site, Koto-ku, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Niigata-shi, , Japan
Research Site, Okayama-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Osakasayama-shi, , Japan
Research Site, Sapporo-shi, , Japan
Research Site, Sendai-shi, , Japan
Research Site, Shiwa-gun, , Japan
Research Site, Sunto-gun, , Japan
Research Site, Yokohama-shi, , Japan
Research Site, Yokohama-shi, , Japan
Research Site, Goyang-si, , Korea, Republic of
Research Site, Gyeonggi-do, , Korea, Republic of
Research Site, Incheon, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Suwon, , Korea, Republic of
Research Site, George Town, , Malaysia
Research Site, Johor Bahru, , Malaysia
Research Site, Kuala Lumpur, , Malaysia
Research Site, Kuala Lumpur, , Malaysia
Research Site, Kuching, , Malaysia
Research Site, Selangor, , Malaysia
Research Site, Białystok, , Poland
Research Site, Bielsko-Biała, , Poland
Research Site, Gliwice, , Poland
Research Site, Piotrków Trybunalski, , Poland
Research Site, Tomaszów Mazowiecki, , Poland
Research Site, Warszawa, , Poland
Research Site, Badalona, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Jaén, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Valencia, , Spain
Research Site, Valencia, , Spain
Research Site, Changhua, , Taiwan
Research Site, Kaohsiung City, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taipei City, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Bangkok, , Thailand
Research Site, Bangkok, , Thailand
Research Site, Chaing Mai, , Thailand
Research Site, Hat Yai, , Thailand
Research Site, Khon Kaen, , Thailand
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Antalya, , Turkey
Research Site, Istanbul, , Turkey
Research Site, Karsiyaka, , Turkey
Research Site, Yenimahalle, , Turkey
Research Site, Aberdeen, , United Kingdom
Research Site, Hampshire, , United Kingdom
Research Site, Leeds, , United Kingdom
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Northwood, , United Kingdom
Research Site, Sutton, , United Kingdom
Research Site, Taunton, , United Kingdom
Research Site, Wirral, , United Kingdom
Research Site, Hanoi, , Vietnam
Research Site, Ho Chi Minh City, , Vietnam
Research Site, Ho Chi Minh, , Vietnam
Research Site, Vinh, , Vietnam
Contact Details
Name: Robert Haddad, MD
Affiliation: Dana Farber Cancer Institute Massachusetts, USA
Role: STUDY_CHAIR
Name: Lisa Licitra, MD
Affiliation: Fondazione IRCCS Istituto Nazionale dei Tumori and University of Milan Milan, Italy
Role: STUDY_CHAIR
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