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Spots Global Cancer Trial Database for Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29

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Trial Identification

Brief Title: Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29

Official Title: Phase II Study of Short-course Radiotherapy Followed by Consolidation Chemotherapy With the Triplet FOLFOXIRI as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: the ShorTrip Study

Study ID: NCT05253846

Study Description

Brief Summary: The aim of the ShorTrip trail is to evaluate the activity and the safety of total neoadjuvant strategy with FOLFOXIRI as consolidation therapy preceded by short-course radiotherapy and followed by surgery in LARC patients.

Detailed Description: This is a prospective, open-label, multicentre, phase II single arm trial. Eligible patients with middle-high LARC will receive short-course radiotherapy followed by consolidation chemotherapy with FOLFOXIRI and surgery. The primary objective of this trial is to evaluate the rate of complete pathologic response (pCR)

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

U.O. Oncologia Medica 2 Universitaria - Azienda Ospedaliero-Universitaria Pisana Dipartimento di Ricerca Traslazionale e Nuove Tecnologie - University of Pisa, Pisa, , Italy

Contact Details

Name: Roberto Moretto, MD

Affiliation: Azienda Ospedaliero, Universitaria Pisana

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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