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Brief Title: Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to Gefitinib
Official Title: Tyrosine Kinase Inhibitors in DyplAsia of Lung Epithelium
Study ID: NCT01405846
Brief Summary: We are going to use a special type of bronchoscopy test to examine patients who have had previous surgical treatment for lung cancer or head and neck cancer. The aim is to determine a) whether we can identify precancerous changes in their airways b) whether this type of testing is acceptable and c) get an initial idea of whether a new drug called gefitinib has any effect on precancerous areas in the airway.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Papworth Hospital NHS Trust, Papworth Everard, Cambs, United Kingdom
Name: Tim Eisen, Professor
Affiliation: Papworth Hospital NHS Trust
Role: STUDY_CHAIR
Name: Robert Rintoul, Dr
Affiliation: Papworth Hospital NHS Trust
Role: PRINCIPAL_INVESTIGATOR