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Brief Title: Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer
Official Title: Radiofrequency Ablation of Pulmonary Malignancy
Study ID: NCT00024076
Brief Summary: RATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. CT-guided radiofrequency ablation may be effective treatment for lung cancer. PURPOSE: Phase II trial to study the effectiveness of radiofrequency ablation in treating patients who have refractory or advanced lung cancer.
Detailed Description: OBJECTIVES: * Determine the safety and toxicity of radiofrequency ablation in patients with refractory or advanced pulmonary malignancies. * Determine the efficacy of this treatment, in terms of local control, in these patients. * Determine whether CT scan is a reasonable imaging assessment tool for treatment delivery and follow-up in these patients. OUTLINE: Patients undergo percutaneous CT-guided radiofrequency ablation directly to the tumor over 2 hours. Patients are followed at 1, 3, 6, and 12 months. PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States
Name: Robert D. Suh, MD
Affiliation: Jonsson Comprehensive Cancer Center
Role: STUDY_CHAIR