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Brief Title: Early Cancer Detection Test - Lung Cancer China
Official Title: Clinic Validation of Autoantibody Panel for Lung Cancer Diagnosis in Chinese Population
Study ID: NCT04216511
Brief Summary: Lung cancer is the most common cancer in China from both incidence and mortality rate point of view, with significantly lower 5-year survival rate than average. Early detection is the recognized solution. LDCT is more and more popular accepted as an effective screening methodology but leads to numerous indeterminate pulmonary nodules for physicians to distinguish too. The value of autoantibody test in risk assessing of IPNs as well as early detection of lung cancer in high risk population has been demonstrated in clinical practice and trial but mainly in Caucasian. Purpose of this study is to understand the sensitivity, specificity and accuracy of candidate autoantibodies, and consequently explore the autoantibody combination with best clinical performance in Chinese population.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Zhongshan Hospital of Fudan University, Shanghai, Shanghai, China
Shanghai Chest Hospital, Shanghai, , China
Henan Province People's Hospital, Zhengzhou, , China
Name: Chunxue Bai, MD
Affiliation: Fudan University
Role: PRINCIPAL_INVESTIGATOR